RUNX3 (BC013362) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	acute myeloid leukemia gene 2; AML2; CBFA3; core-binding factor, runt domain, alpha subunit 3; FLJ34510; MGC16070; OTTHUMP00000003370; OTTHUMP00000003371; PEA2 alpha C; PEBP2 alpha C; PEBP2aC; polyomavirus enhancer-binding protein 2 alpha C subunit; trans
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC013362 edited GGCGGCCCACTCTGCTCTGTCAGCTTCGGAGCTCCTCCACCCTGGCTGCCGAAAGCCCCT TCCCGCCATCTAATGATACACTCTGCATACGCTTCTGTTGAGAATTTGTGGCTAGACATT CCTGTGGGACCGGGAATCCAAATTCTTGGTAGCTAGAGGAAAAAAAAATAAAACAACAGC CAACCAAGTGAATCCCAACCCAACCCCCTGAAGGGCTGAAAATTCTCGCCTTCTTCAGAG CGGGGCATGGCATCGAACAGCATCTTCGACTCCTTCCCGACCTACTCGCCGACCTTCATC CGCGACCCAAGCACCAGCCGCCGCTTCACACCTCCCTCCCCGGCCTTCCCCTGCGGCGGC GGCGGCGGCAAGATGGGCGAGAACAGCGGCGCGCTGAGCGCGCAGGCGGCCGTGGGGCCC GGAGGGCGCGCCCGGCCCGAGGTGCGCTCGATGGTGGACGTGCTGGCGGACCACGCAGGC GAGCTCGTGCGCACCGACAGCCCCAACTTCCTCTGCTCCGTGCTGCCCTCGCACTGGCGC TGCAACAAGACGCTGCCCGTCGCCTTCAAGGTGGTGGCATTGGGGGACGTGCCGGATGGT ACGGTGGTGACTGTGATGGCAGGCAATGACGAGAACTACTCCGCTGAGCTGCGCAATGCC TCGGCCGTCATGAAGAACCAGGTGGCCAGGTTCAACGACCTTCGCTTCGTGGGCCGCAGT GGGCGAGGGAAGAGTTTCACCCTGACCATCACTGTGTTCACCAACCCCACCCAAGTGGCG ACCTACCACCGAGCCATCAAGGTGACCGTGGACGGACCCCGGGAGCCCAGACGGCACCGG CAGAAGCTGGAGGACCAGACCAAGCCGTTCCCTGACCGCTTTGGGGACCTGGAACGGCTG CGCATGCGGGTGACACCGAGCACACCCAGCCCCCGAGGCTCACTCAGCACCACAAGCCAC TTCAGCAGCCAGCCCCAGACCCCAATCCAAGGCACCTCGGAACTGAACCCATTCTCCGAC CCCCGCCAGTTTGACCGCTCCTTCCCCACGCTGCCAACCCTCACGGAGAGCCGCTTCCCA GACCCCAGGATGCATTATCCCGGGGCCATGTCAGCTGCCTTCCCCTACAGCGCCACGCCC TCGGGCACGAGCATCAGCAGCCTCAGCGTGGCGGGCATGCCGGCCACCAGCCGCTTCCAC CATACCTACCTCCCGCCACCCTACCCGGGGGCCCCGCAGAACCAGAGCGGGCCCTTCCAG GCCAACCCGTCCCCCTACCACCTCTACTACGGGACATCCTCTGGCTCCTACCAGTTCTCC ATGGTGGCCGGCAGCAGCAGTGGGGGCGACCGCTCACCTACCCGCATGCTGGCCTCTTGC ACCAGCAGCGCTGCCTCTGTCGCCGCCGGCAACCTCATGAACCCCAGCCTGGGCGGCCAG AGTGATGGCGTGGAGGCCGACGGCAGCCACAGCAACTCACCCACGGCCCTGAGCACGCCA GGCCGCATGGATGAGGCCGTGTGGCGGCCCTACTGACCGCCCTGGTGGACTCCTCCCGCT GGAGGCGGGGACCCTAACAACCTTCAAGACCAGTGATGGGCCGGCTCCGAGGCTCCGGGC GGGAATGGGACCTGCGCTCCAGGGTGGTCTCGGTCCCAGGGTGGTCCCAGCTGGTGGGAG CCTCTGGCTGCATCTGTGCAGCCACATCCTTGTACAGAGGCATAGGTTACCACCCCCACC CCGGCCCGGGATACTGCCCCCGGCCCAGATCCTGGCCGTCTCATCCCATACTTCTGTGGG GAATCAGCCTCCTGCCACCCCCCCGGAAGGACCTCACTGTCTCCAGCTATGCCCAGTGCT GCATGGGACCCATGTCTCCTGGGACAGAGGCCATCTCTCTTCCAGAGAGAGGCAGCATTG GCCCACAGGATAAGCCTCAGGCCCTGGGAAACCTCCCGACCCCTGCACCTTCGTTGGAGC CCCTGCATCCCCTGGGTCCAGCCCCCTCTGCATTTACACAGATTTGAGTCAGAACTGGAA AGTGTCCCCCACCCCCACCACCCTCGAGCGGGGTTCCCCTCATTGTACAGATGGGGCAGG ACCCAGCACGCTGCTGGCAGAGATGGTTTGAGAACACATCCAAGCCAGTCCCCCCAGCCC AGCTTCCCCTCCGTTCCTAACTGTTGGCTTTCCCCCAGCCGCACGGGTCCCAGGCCCCAG AGAAGATGAGTCTATGGCATCAGGTTCTTAAACCCAGGAAAGCACCTACAGACCGGCTCC TCCATGCACTTTACCAGCTCAACGCATCCACTCTCTGTTCTCTTGGCAGGGCGGGGGAGG GGGGATAGGAGGTCCCCTTTCCCCTAGGTGGTCTCATAATTCCATTTGTGGAGAGAACAG GAGGGCCAGATAGATAGGTCCTAGCAGAAGGCATTGAGGTGAGGGATCATTTTGGGTCAG ACATCAATGTCCCTGTCCCCCCTGGGTCCAGCCAAGCTGTGCCCCATCCCCCAAGCCTCC TGGGAGGATCCAGCCAAATCTTGCGACTCCTGGCACACACCTGTCTGTAACCTGTTTTGT GCTCTGAAAGCAAATAGTCCTGAGCAAAAAAAACAAAAAAAACAAAAAAAAAAAAAAAAA A
Restriction Sites	Please inquire
ACCN	BC013362
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC013362.2, AAH13362.1
RefSeq Size	2641 bp
Locus ID	864
Protein Families	Transcription Factors
Gene Summary	This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

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