SOCS4 (BC008618) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC008618 edited CAAATGTAGACCCTGCACTCAATGTGCTTACCCTGTAGGAGCAGAGACAGATAAGTCAGA TTTCAGTCTGGGGCAGGTGGAGCCATGATGAAGCCTTCCCCACACTTGTGAGACCACTTT GGGAGATGGGAGGCATCCCCAAGCTGGGTCAGCTTGAACCCACCAGCAGGGGTGAGCAGG TCTTCTGCATACAGGGTTTTCAGAGACACCGGGCTGGCCCGAGACACCTGAGCTGCATCA GAGAACAATAGGTTCTGGGGCCTGCTGCGGCTGAGGTGCCGGGTGGGCACGCAGCTGGGG GCACCCAACAATGACCACCAGGGCACTAGTGTTCATCGGGTACCACCCCGTGTGCCAGGG AATGTGGACTCAGTGCCTGCCATGTCCCTTGCTCCGTGCAAGCAGACCACGTCTGTGCTC TCACTGAATCCTCTGGAGGGACACCTCTCTCTACCTCTGTTTCCCTTTGGTAGACGTCTG ATAACACACGTCGTATTCTCTTCACTCAGAATTCATAGATGTCGGCTGGGTGCGGTGGCT TATGCCTGTAATCTCAGCACTTTGGGAGGCCGAAGGGGACAGGATCGCTTGAGCTCGGGA ATTCAAGACCAGCCTGGGCAACATGGCTAAGTCTCCTCTCTACAAAAAAAATACAAATAA TTAGCCAGGCATGGTGATGCATAACTTTAACCCCAACTAATGGGGGGGCTGAGATGGGTG GATCACTTTTGGGCCTGGGAGGCGGAGGTAGCAGTGAGTGGAGATCACGTCACTGTACTC TAGCCTAGGAGACAGAGCAAGACTCCATCTCAAAAAAAGAAAACAAAAAAGAATTCATAG ATGTAACATTTTGCCTTTGATACTTCTGATCTTTGTTAATCATGAAAAATACTCACTGGG CACAGTGGCTCACGCCTGTAATTCCAGCACTTTGGGAGGCCGAGGCGGGTGGACCTCCTC AAGTCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTAAAACCCCGTCTCTACTAAAAATA CAAAAATTAGCTGGGCATGGTGGCACACCCCTATAATCCCAGCTACTTGGGAGGCTGAGG TGGGAGGATTGCACGAACCTGGGAGGCAACCAGCTCTGCTCACGTGAGCTGAGCTCACGC CACTGCACTCCAGCCTGGGCAACAGAGCGAGACTAAGTCTCAAAAAGAAAAAAAAAAAAG AAAAATACCAGAGGTTGAAGTCCTCCCATCCCCCTTTCTTACAGGAAGTAACTGTCGAGA AATTGTGTGTCTGACAACCCCTGTTGTCCTCTCAGTCAAGCAGTGTGTGCCGTAGTTTCA GATGTTTGACCCTTTATGCAGATGACGACATAGTGTGCGTTTTGTTCCAAGCTTTTTTCT CTTACTCGACGTTATTTTTTTTAGGTCTAGATGGTCCAACTAAATCTCATTGAGTTCTGT AAGCAGCTGGTTACCTCCATTTCCACACTTTCCATTTAGGAAGCTAAGGCTTAAAAAGAT GAAGCCCCTGCCAGGCATGGTGGCTCATGTCTGTAATCCCTTTGAGAGGCTGAGCTGGGA GGATCGCTTGAATCTAAGAGTGTGAGACCAGCCTGGACAGCCTAGCAAGAACCCATCTCT GCAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for BC008618 unedited GGTCATAATTTGTATACGACTCATATAGGCGGCCGCGTATTCACATCTGGTACCACCCCG TGTGCCAGGGAATGTGGACTCAGTGCCTGCCATGTCCCTTGCTCCGTGCAAGCAGACCAC GTCTGTGCTCTCACTGAATCCTCTGGAGGGACACCTCTCTCTACCTCTGTTTCCCTTTGG TAGACGTCTGATAACACACGTCGTATTCTCTTCACTCAGAATTCATAGATGTCGGCTGGG TGCGGTGGCTTATGCCTGTAATCTCAGCACTTTGGGAGGCCGAAGGGGACAGGATCGCTT GAGCTCGGGAATTCAAGACCAGCCTGGGCAACATGGCTAAGTCTCCTCTCTACAAAAAAA ATACAAATAATTAGCCAGGCATGGTGATGCATAACTTTAACCCCAACTAATGGGGGGGCT GAGATGGGTGGATCACTTTTGGGCCTGGGAGGCGGAGGTAGCAGTGAGTGGAGATCACGT CACTGTACTCTAGCCTAGGAGACAGAGCAAGACTCCATCTCAAAAAAAGAAAACAAAAAA GAATTCATAGATGTAACATTTTGCCTTTGATACTTCTGATCTTTGTTAATCATGAAAAAT ACTCACTGGGCACAGTGGCTCACGCCTGTAATTCCAGCACTTTGGGAGGCCGAGGCGGGT GGACCTCCTCAAGTCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTAAAACCCCGTCTCT ACTAAAAATACAAAAATTAGCTGGGCATGGTGGCACACCCCTATAATCCCAGCTACTTGG GGAGGCTGAAGTGGGAGGATTGCACGAACCCTGGGAGGCAACCAGCTCTGCTCACGTGAG CTGAACTCACGCCACTGCACTCCAACCTGGGGCAACAGAGCGAGACTAAATTCTCAAAAA AAAAAAAAAAAAAGAAAATCCCCGGAGTTTGAAGTCCTCCT
Restriction Sites	Please inquire
ACCN	BC008618
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC008618.1
RefSeq Size	1637 bp
Locus ID	122809
Protein Families	Druggable Genome
Protein Pathways	Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus
Gene Summary	The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

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