CHRNA3 (BC006114) Human Untagged Clone
CAT#: SC126406
CHRNA3 (untagged)-Human cholinergic receptor, nicotinic, alpha polypeptide 3, mRNA (cDNA clone MGC:12991 IMAGE:3503197), complete cds
CNY 3,656.00
货期*
现货
规格
Cited in 1 publication. |
Product images
经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | Cholinergic receptor, neuronal nicotinic, alpha polypeptide-3; cholinergic receptor, nicotinic, alpha 3; cholinergic receptor, nicotinic, alpha polypeptide 3; LNCR2; MGC104879; neuronal nicotinic acetylcholine receptor, alpha3 subunit; PAOD2 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for BC006114 edited
GTCCTTCCCAGGGTGTGTTAGCGTCTCTCCTACGGCGCCCGCCTAGCCCGGTGGTCCCAA CCCCCTGCGGGAGCTGCACACGCCCCGGAAACCTGGGACAGAAACTGAGTCCCTCTCCTT CCTGGTGGTGGTGACAGCACCTGCTCAGATCTGGTCGGACGCCGCCGGCCGGAGCACCCA GCCCGGCGGAGAAGGAGCTCGCCCGGCGCTGGGGACTGGGACCTGGAGCCCCTTCCCCTA CCGCACGTACGCCCCGCCCCGCGCACGCCCGCCCGCCCGCCCGCGCCTGGCGCAGCTTCA CTCCGGATGGTTCCTGTCCTCCCGCGGGTCCGAGGGCGCTGGAAACCCAGCGGCGGCGAA GCGGAGAGGAGCCCCGCGCGTCTCCGCCCGCACGGCTCCAGGTCTGGGGTCTGCGCTGGA GCCGCGCGGGGAGAGGCCGTCTCTGCGACCGCCGCGCCCGCTCCCGACCGTCCGGGTCCG CGGCCAGCCCGGCCACCAGCCATGGGCTCTGGCCCGCTCTCGCTGCCCCTGGCGCTGTCG CCGCCGCGGCTGCTGCTGCTGCTGCTGCTGTCTCTGCTGCCAGTGGCCAGGGCCTCAGAG GCTGAGCACCGTCTATTTGAGCGGCTGTTTGAAGATTACAATGAGATCATCCGGCCTGTA GCCAACGTGTCTGACCCAGTCATCATCCATTTCGAGGTGTCCATGTCTCAGCTGGTGAAG GTGGATGAAGTAAACCAGATCATGGAGACCAACCTGTGGCTCAAGCAAATCTGGAATGAC TACAAGCTGAAATGGAACCCCTCTGACTATGGTGGGGCAGAGTTCATGCGTGTCCCTGCA CAGAAGATCTGGAAGCCAGACATTGTGCTGTATAACAATGCTGTTGGGGATTTCCAGGTG GACGACAAGACCAAAGCCTTACTCAAGTACACTGGGGAGGTGACTTGGATACCTCCGGCC ATCTTTAAGAGCTCCTGTAAAATCGACGTGACCTACTTCCCGTTTGATTACCAAAACTGT ACCATGAAGTTCGGTTCCTGGTCCTACGATAAGGCGAAAATCGATCTGGTCCTGATCGGC TCTTCCATGAACCTCAAGGACTATTGGGAGAGCGGCGAGTGGGCCATCATCAAAGCCCCA GGCTACAAACACGACATCAAGTACAACTGCTGCGAGGAGATCTACCCCGACATCACATAC TCGCTGTACATCCGGCGCCTGCCCTTGTTCTACACCATCAACCTCATCATCCCCTGCCTG CTCATCTCCTTCCTCACTGTGCTCGTCTTCTACCTGCCCTCCGACTGCGGTGAGAAGGTG ACCCTGTGCATTTCTGTCCTCCTCTCCCTGACGGTGTTTCTCCTGGTGATCACTGAGACC ATCCCTTCCACCTCGCTGGTCATCCCCCTGATTGGAGAGTACCTCCTGTTCACCATGATT TTTGTAACCTTGTCCATCGTCATCACCGTCTTCGTGCTCAACGTGCACTACAGAACCCCG ACGACACACACAATGCCCTCATGGGTGAAGACTGTATTCTTGAACCTGCTCCCCAGGGTC ATGTTCATGACCAGGCCAACAAGCAACGAGGGCAACGCTCAGAAGCCGAGGCCCCTCTAC GGTGCCGAGCTCTCAAATCTGAATTGCTTCAGCCGCGCAGAGTCCAAAGGCTGCAAGGAG GGCTACCCCTGCCAGGACGGGATGTGTGGTTACTGCCACCACCGCAGGATAAAAATCTCC AATTTCAGTGCTAACCTCACGAGAAGCTCTAGTTCTGAATCTGTTGATGCTGTGCTGTCC CTCTCTGCTTTGTCACCAGAAATCAAAGAAGCCATCCAAAGTGTCAAGTATATTGCTGAA AATATGAAAGCACAAAATGAAGCCAAAGAGGAACAAAAAGCCCAAGAGATCCAACAATTG AAACGAAAAGAAAAGTCCACAGAAACATCCGATCAAGAACCTGGGCTATGAATTTCCAAT CTTCAACAACCTGTTAGGAAAAAAATAAAAATGCATTAAATAATTGTAAAAAAAAAAAAA AAAAAA >OriGene 5' read for BC006114 unedited
NAAGGTCGNCATTTGTATACGACTCATATAGGCGGACCGCGAATTCGCACGAGGTCCTTC CCAGGTGTGTTAGCGTCTCTCCTACGGCGCCCGCCTAGCCCGGTGGTCCCAACCCCCTGC GGGAGCTGCACACGCCCCGGAAACCTGGGACAGAAACTGAGTCCCTCTCCTTCCTGGTGG TGGTGACAGCACCTGCTCAGATCTGGTCGGACGCCGCCGGCCGGAGCACCCAGCCCGGCG GAGAAGGAGCTCGCCCGGCGCTGGGGACTGGGACCTGGAGCCCCTTCCCCTACCGCACGT ACGCCCCGCCCCGCGCACGCCCGCCCGCCCGCCCGCGCCTGGCGCAGCTTCACTCCGGAT GGTTCCTGTCCTCCCGCGGGTCCGAGGGCGCTGGAAACCCAGCGGCGGCGAAGCGGAGAG GAGCCCCGCGCGTCTCCGCCCGCACGGCTCCAGGTCTGGGGTCTGCGCTGGAGCCGCGCG GGGAGAGGCCGTCTCTGCGACCGCCGCGCCCGCTCCCGACCGTCCGGGTCCGCGGCCAGC CCGGCCACCAGCCATGGGCTCTGGCCCGCTCTCGCTGCCCCTGGCGCTGTCGCCGCCGCG GCTGCTGCTGCTGCTGCTGCTGTCTCTGCTGCCAGTGGCCAGGGCCTCAGAGGCTGAGCA CCGTCTATTTGAGCGGCTGTTTGAAGATTACAATGAGATCATCCGGCCTGTAGCCAACGT GTCTGACCCAGTCATCATCCATTTCGAGGTGTCCATGTCTCAGCTGGTGAAGGTGGATGA AGTAAACCAGATCATGGAGACCAACCTGTGGCTCAAGCAAATCTGGNAATGACTACAGCT GAAATGGAACCCCTCTGACTATGGTGGGGCAGAGTTCATGCGTGTCCCTGCACAGAAGAT CTGGAAGCCAGA |
Restriction Sites | Please inquire |
ACCN | BC006114 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | BC006114.1, AAH06114.1 |
RefSeq Size | 2046 bp |
RefSeq ORF | 1467 bp |
Locus ID | 1136 |
Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
Gene Summary | This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Crystal Structures of Human GlyRα3 Bound to Ivermectin
,Huang, X;Chen, H;Shaffer, PL;,
Structure
,PubMed ID 28479061
[CHRNA3]
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