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SCUBE3 (NM_152753) Human Untagged Clone
CAT＃: SC126481
SCUBE3 (untagged)-Human signal peptide, CUB domain, EGF-like 3 (SCUBE3)
CNY 7,280.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CEGF3; SSFSC2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_152753 edited
CTCTCTCCCGGCGAAGCTGGGAATTGGGTGGGATTACACGGAGCAGCCCCGCCGCCGCCG CTGGCAGAGGCCGGCTTGGAGAGGGCGGGGGTTCCCCTCCGTCAGTCGCCCCTGGCGCCC CTCGCCTTGTCGCACTCTCCGCCTCGCTCTCCCCGACGTCCGGCCAGGAGGAGCCGGTAG CATCGGGAGCCTCGCGCCGAGGGCGCCGCGGTCCGCGCCCCGCGACTGCAGCCCCCGGCC TGGCCCCGGCGGGGCGCCCCCTCCCCTCCCCCTCCTGCGAGCTGGGATCCGGCCGGCTTC CGCCCTCCCCTGGCCGCGAGACCGGCCCCGGCGGCTGGGCCGCCAGTAGCTCCAGCCATG GGCTCGGGGCGCGTACCCGGGCTCTGCCTGCTTGTCCTGCTGGTCCACGCCCGCGCCGCC CAGTACAGCAAAGCCGCGCAAGATGTGGATGAGTGTGTGGAGGGGACTGACAACTGCCAC ATCGATGCTATCTGCCAGAACACCCCGAGGTCATACAAGTGCATCTGCAAGTCTGGCTAC ACAGGGGACGGCAAACACTGCAAAGACGTGGATGAGTGCGAGCGAGAGGATAATGCAGGT TGTGTGCATGACTGTGTCAACATCCCTGGCAATTACCGGTGTACCTGCTATGATGGATTC CACCTGGCACATGACGGACACAACTGTCTGGATGTGGACGAGTGTGCCGAGGGCAACGGC GGCTGTCAGCAGAGCTGTGTCAACATGATGGGCAGCTATGAGTGCCACTGCCGGGAAGGC TTCTTCCTCAGCGACAACCAGCATACCTGTATCCAGCGGCCAGAAGGAATGAACTGCATG AACAAGAACCACGGCTGTGCCCACATTTGCCGGGAGACACCCAAGGGGGGTATTGCCTGT GAATGCCGTCCTGGCTTTGAGCTTACCAAGAACCAACGGGACTGTAAATTGACATGCAAC TATGGTAACGGCGGCTGCCAGCACACGTGTGATGACACAGAGCAGGGTCCCCGGTGCGGC TGCCATATCAAGTTTGTGCTCCATACCGACGGGAAGACATGCATCGAGACCTGTGCTGTC AACAACGGGGGCTGTGACAGTAAGTGCCATGATGCAGCGATTGGTGTCCACTGCACCTGC CCTGTGGGCTTCATGCTGCAGCCAGACAGGAAGACGTGCAAAGATATAGATGAGTGCCGC TTAAACAACGGGGGCTGTGACCATATTTGCCGCAACACAGTGGGCAGCTTCGAATGCAGT TGCAAGAAAGGCTATAAGCTTCTCATCAATGAGAGGAACTGCCAGGATATAGACGAGTGT TCCTTTGATCGAACCTGTGACCACATATGTGTCAACACACCAGGAAGCTTCCAGTGTCTC TGCCATCGTGGCTACCTGTTGTATGGTATCACCCACTGTGGGGATGTGGATGAATGCAGC ATCAACCGGGGAGGTTGCCGCTTTGGCTGCATCAACACTCCTGGCAGCTACCAGTGTACC TGCCCAGCAGGCCAGGGTCGGCTGCACTGGAATGGCAAAGATTGCACAGAGCCACTGAAG TGTCAGGGCAGTCCTGGGGCCTCGAAAGCCATGCTCAGCTGCAACCGGTCTGGCAAGAAG GACACCTGTGCCCTGACCTGTCCCTCCAGGGCCCGATTTTTGCCAGAGTCTGAGAATGGC TTCACGGTGAGCTGTGGGACCCCCAGCCCCAGGGCTGCTCCAGCCCGAGCTGGCCACAAT GGGAACAGCACCAACTCCAACCACTGCCATGAGGCTGCAGTGCTGTCCATTAAACAACGG GCCTCCTTCAAGATCAAGGATGCCAAATGCCGTTTGCACCTGCGAAACAAAGGCAAAACA GAGGAGGCTGGCAGAATCACAGGGCCAGGTGGTGCCCCCTGCTCTGAATGCCAGGTCACC TTCATCCACCTTAAGTGTGACTCCTCTCGGAAGGGCAAGGGCCGACGGGCCCGGACCCCT CCAGGCAAAGAGGTCACAAGGCTCACCCTGGAACTGGAGGCAGAGGTCAGAGCCGAAGAA ACCACAGCCAGCTGTGGGCTGCCCTGCCTCCGACAGCGAATGGAACGGCGGCTGAAAGGA TCCCTGAAGATGCTCAGAAAGTCCATCAACCAGGACCGCTTCCTGCTGCGCCTGGCAGGC CTTGATTATGAGCTGGCCCACAAGCCGGGCCTGGTAGCCGGGGAGCGAGCAGAGCCGATG GAGTCCTGTAGGCCCGGGCAGCACCGTGCTGGGACCAAGTGTGTCAGCTGCCCGCAGGGA ACGTATTACCACGGCCAGACGGAGCAGTGTGTGCCATGCCCAGCGGGCACCTTCCAGGAG AGAGAAGGGCAGCTCTCCTGCGACCTTTGCCCTGGGAGTGATGCCCACGGGCCTCTTGGA GCCACCAACGTCACCACGTGTGCAGGTCAGTGCCCACCTGGCCAACACTCTGTAGATGGG TTCAAGCCCTGTCAGCCATGCCCACGTGGCACCTACCAACCTGAAGCAGGACGGACCCTA TGCTTCCCTTGTGGTGGGGGCCTCACCACCAAGCATGAAGGGGCCATTTCCTTCCAAGAC TGTGACACCAAAGTCCAGTGCTCCCCAGGGCACTACTACAACACCAGCATCCACCGCTGT ATTCGCTGTGCCATGGGCTCCTATCAGCCCGACTTCCGTCAGAACTTCTGCAGCCGCTGT CCAGGAAACACAAGCACAGACTTTGATGGCTCTACCAGTGTGGCCCAATGCAAGAATCGT CAGTGTGGTGGGGAGCTGGGTGAGTTCACTGGCTATATTGAGTCCCCCAACTACCCGGGC AACTACCCAGCTGGTGTGGAGTGCATCTGGAACATCAACCCCCCACCCAAGCGCAAGATC CTTATCGTGGTACCAGAGATCTTCCTGCCATCTGAGGATGAGTGTGGGGACGTCCTCGTC ATGAGAAAGAACTCATCCCCATCCTCCATTACCACTTATGAGACCTGCCAGACCTACGAG CGTCCCATTGCCTTCACTGCCCGTTCCAGGAAGCTCTGGATCAACTTCAAGACAAGCGAG GCCAACAGCGCCCGTGGCTTCCAGATTCCCTATGTTACCTATGATGAGGACTATGAGCAG CTGGTAGAAGACATTGTGCGAGATGGCCGGCTCTATGCCTCTGAAAACCACCAGGAGATT TTAAAGGACAAGAAGCTCATCAAGGCCTTCTTTGAGGTGCTAGCCCACCCCCAGAACTAC TTCAAGTACACAGAGAAACACAAGGAGATGCTGCCAAAATCCTTCATCAAGCTGCTCCGC TCCAAAGTTTCCAGCTTCCTGAGGCCCTACAAATAGTAACCCTAGGCTCAGAGACCCAAT TTTTTAAGCCCCCAGACTCCTTAGCCCTCAGAGCCGGCAGCCCCCTACCCTCAGACAAGG AACTCTCTCCTCTCTTTTTGGAGGGAAAAAAAAAATATCACTACACAAACCAGGCACTCT CCCTTTCTGTCTTTCTAGTTTCCTTTCCTTGTCTCTCTCTGCCTGCCTCTCTACTGTTCC CCCTTTTCTAACACACTACCTAGAAAAGCCATTCAGTACTGGCTCTAGTCCCCGTGAGAT GTAAAGAAACAGTACAGCCCCTTCCACTGCCCATTTTACCAGCTCACATTCCCGACCCCA TCAGCTTGGAAGGGTGCTAGAGGCCCATCAAGGAAGTGGGTCTGGTGGGAAACGGGGAGG GGAAAGAAGGGCTTCTGCCATTATAGGGTTGTGCCTTGCTAGTCAGGGGCCAAAATGTCC CCTGGCTCTGCTCCCTAGGGTGATTCTAACAGCCCAGGGTCCTGCCAAAGAAGCCTTTGA TTTACAGGCTTAATGCCAGCACCAGTCCTCTGGGGCACATGGTTTGAGCTCTGGACTTCC CACATGGCCAGCTTTCTTGTCTATACAGATCCTCTCTTTCTTTCCCTACGTCTGCCTGGG GTCTACTCCATAAGGGTTTACAAATGGCCCACAACACTGAGTTAGTGGACACCGGCTAAA TGAGGAAGAGCAGCAGGCATTGTCATGGTGAATGCCCCGCTGTAGCTCCCTGAGAGAAAG ACTGTAACTCTGCAGGACAGAAACAAGGTTTTAAAGCATTGCCAAAAAAAAAAAAAAAAA AA >OriGene 5' read for NM_152753 unedited
NGGGCGGTTCGGATTTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGCT CTCTCCCGGCGAAGCTGGGAATTGGGTGGGATTACACGGAGCAGCCCCGCCGCCGCCGCT GGCAGAGGCCGGCTTGGAGAGGGCGGGGGTTCCCCTCCGTCAGTCGCCCCTGGCGCCCCT CGCCTTGTCGCACTCTCCGCCTCGCTCTCCCCGACGTCCGGCCAGGAGGAGCCGGTAGCA TCGGGAGCCTCGCGCCGAGGGCGCCGCGGTCCGCGCCCCGCGACTGCAGCCCCCGGCCTG GCCCCGGCGGGGCGCCCCCTCCCCTCCCCCTCCTGCGAGCTGGGATCCGGCCGGCTTCCG CCCTCCCCTGGCCGCGAGACCGGCCCCGGCGGCTGGGCCGCCAGTAGCTCCAGCCATGGG CTCGGGGCGCGTACCCGGGCTCTGCCTGCTTGTCCTGCTGGTCCACGCCCGCGCCGCCCA GTACAGCAAAGCCGCGCAAGATGTGGATGAGTGTGTGGAGGGGACTGACAACTGCCACAT CGATGCTATCTGCCAGAACACCCCGAGGTCATACAAGTGCATCTGCAAGTCTGGCTACAC AGGGGACGGCAAACACTGCAAAGACGTGGATGAGTGCGAGCGAGAGGATAATGCAGGTTG TGTGCATGACTGTGTCAACATCCCTGGCAATTACCGGTGTACCTGCTATGATGGATTCCA CCTGGCACATGACGGACACAACTGTCTGGATGTGGACCAGTGTGCCGAGGGCAACGGCGG CTGTCAGCAGAGCTGTGTCAACATGATGGGCAGCTATGAGTGCCACTTGCCGGGAAGGCT TCTTCCTTAGCGACAACCAGCATACCCTGTATCCAGCGGCCAGAATGA |
| Restriction Sites | Please inquire |
| ACCN | NM_152753 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152753.2, NP_689966.2 |
| RefSeq Size | 5115 bp |
| RefSeq ORF | 2982 bp |
| Locus ID | 222663 |
| UniProt ID | Q8IX30 |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | This gene encodes a member of the signal peptide, complement subcomponents C1r/C1s, Uegf, bone morphogenetic protein-1 and epidermal growth factor-like domain containing protein family. Overexpression of this gene in human embryonic kidney cells results in secretion of a glycosylated form of the protein that forms oligomers and tethers to the cell surface. This gene is upregulated in lung cancer tumor tissue compared to healthy tissue and is associated with loss of the epithelial marker E-cadherin and with increased expression of vimentin, a mesenchymal marker. In addition, the protein encoded by this gene is a transforming growth factor beta receptor ligand, and when secreted by cancer cells, it can be cleaved in vitro to release the N-terminal epidermal growth factor-like repeat domain and the C-terminal complement subcomponents C1r/C1s domain. Both the full length protein and C-terminal fragment can bind to the transforming growth factor beta type II receptor to promote the epithelial-mesenchymal transition and tumor angiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208610 | SCUBE3 (Myc-DDK-tagged)-Human signal peptide, CUB domain, EGF-like 3 (SCUBE3) |
CNY 9,790.00 |
|
| RC208610L3 | Lenti ORF clone of Human signal peptide, CUB domain, EGF-like 3 (SCUBE3), Myc-DDK-tagged |
CNY 11,690.00 |
|
| RC208610L4 | Lenti ORF clone of Human signal peptide, CUB domain, EGF-like 3 (SCUBE3), mGFP tagged |
CNY 11,690.00 |
|
| RG208610 | SCUBE3 (tGFP-tagged) - Human signal peptide, CUB domain, EGF-like 3 (SCUBE3) |
CNY 10,740.00 |
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