United States
Germany
Japan
United Kingdom
China
PTS (NM_000317) Human Untagged Clone
CAT＃: SC126853
PTS (untagged)-Human 6-pyruvoyltetrahydropterin synthase (PTS)
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PTPS |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126853 sequence for NM_000317 edited (data generated by NextGen Sequencing)
ATGAGCACGGAAGGTGGTGGCCGTCGCTGCCAGGCACAAGTGTCCCGCCGCATCTCCTTC AGCGCGAGCCACCGATTGTACAGTAAATTTCTAAGTGATGAAGAAAACTTGAAACTGTTT GGGAAATGCAACAATCCAAATGGCCATGGGCACAATTATAAAGTTGTGGTGACAGTACAT GGAGAGATTGACCCTGCTACGGGAATGGTTATGAATCTGGCTGATCTCAAAAAATATATG GAGGAGGCGATTATGCAGCCCCTTGATCATAAGAATCTGGATATGGATGTGCCATACTTT GCAGATGTGGTGAGCACGACTGAAAATGTAGCTGTTTATATCTGGGACAACCTCCAGAAA GTTCTTCCTGTAGGAGTTCTTTATAAAGTAAAAGTATACGAAACTGACAATAATATTGTG GTTTATAAAGGAGAATAG Clone variation with respect to NM_000317.2 >OriGene 5' read for NM_000317 unedited
GTATTTGTATACGACNACTATAGGGCGGCCGCGAATTCGCACGAGGGGNGAAGATGAGCA CGGAAGGTGGTGGCCGTCGCTGCCAGGCACAAGTGTCCCGCCGCATCTCCTTCAGCGCGA GCCACCGATTGTACAGTAAATTTCTAAGTGATGAAGAAAACTTGAAACTGTTTGGGAAAT GCAACAATCCAAATGGCCATGGGCACAATTATAAAGTTGTGGTGACAGTACATGGAGAGA TTGACCCTGCTACGGGAATGGTTATGAATCTGGCTGATCTCAAAAAATATATGGAGGAGG CGATTATGCAGCCCCTTGATCATAAGAATCTGGATATGGATGTGCCATACTTTGCAGATG TGGTGAGCACGACTGAAAATGTAGCTGTTTATATCTGGGACAACCTCCAGAAAGTTCTTC CTGTAGGAGTTCTTTATAAAGTAAAAGTATACGAAACTGACAATAATATTGTGGTTTATA AAGGAGAATAGCTATTGGGGTTAGCATTGCACAAAGCCCAGTTTCTTTCTGTGTTTGAAA AAGATTTTGATCCCCTTGGAATATTAAGAGGTCAACACGTGATTGTTGTACGTACACATT GTGCTCTGGAGTGCCTATTTATTGAAATCATTGTAAGACCTGTTATAAATTTAAGTCTAT TTAAAACTAAACTTGTAATATACATCCTGAAAATCATTTAGAGAGTCTTTTATTTATAAA TTAAAAATCACTTCATTTTCACAAAANAAAAAAAAAAAAACTCGACTCTAGATTGCGGCC GCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGGCATCCTGTGNACCCTCCCAGTGC CTCTCTGGCCNTGNNAGTGCCCTNCAGTGCCACCAGCCTTGTCTATAAAATAAGTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000317 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000317.1, NP_000308.1 |
| RefSeq Size | 921 bp |
| RefSeq ORF | 438 bp |
| Locus ID | 5805 |
| UniProt ID | Q03393 |
| Domains | PTPS |
| Protein Families | Druggable Genome |
| Protein Pathways | Folate biosynthesis, Metabolic pathways |
| Gene Summary | The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq, Oct 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205199 | PTS (Myc-DDK-tagged)-Human 6-pyruvoyltetrahydropterin synthase (PTS) |
CNY 1,200.00 |
|
| RC205199L1 | Lenti ORF clone of Human 6-pyruvoyltetrahydropterin synthase (PTS), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC205199L2 | Lenti ORF clone of Human 6-pyruvoyltetrahydropterin synthase (PTS), mGFP tagged |
CNY 5,890.00 |
|
| RC205199L3 | Lenti ORF clone of Human 6-pyruvoyltetrahydropterin synthase (PTS), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205199L4 | Lenti ORF clone of Human 6-pyruvoyltetrahydropterin synthase (PTS), mGFP tagged |
CNY 5,890.00 |
|
| RG205199 | PTS (tGFP-tagged) - Human 6-pyruvoyltetrahydropterin synthase (PTS) |
CNY 4,370.00 |
