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EGLN2 (NM_053046) Human Untagged Clone
CAT＃: SC126989
EGLN2 (untagged)-Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 1
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EIT-6; EIT6; HIF-PH1; HIFPH1; HPH-1; HPH-3; PHD1 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126989 sequence for NM_053046 edited (data generated by NextGen Sequencing)
ATGGACAGCCCGTGCCAGCCGCAGCCCCTAAGTCAGGCTCTCCCTCAGTTACCAGGGTCT TCGTCAGAGCCCTTGGAGCCTGAGCCTGGCCGGGCCAGGATGGGAGTGGAGAGTTACCTG CCCTGTCCCCTGCTCCCCTCCTACCACTGTCCAGGAGTGCCTAGTGAGGCCTTGGCAGGG AGTGGGACCCCCAGAGCCACAGCCACCTCTACCACTGCCAGCCCTCTTCGGGACGGTTTT GGCGGGCAGGATGGTGGTGAGCTGCGGCCGCTGCAGAGTGAAGGCGCTGCAGCGCTGGTC ACCAAGGGGTGCCAGCGATTGGCAGCCCAGGGCGCACGGCCTGAGGCCCCCAAACGGAAA TGGGCCGAGGATGGTGGGGATGCCCCTTCACCCAGCAAACGGCCCTGGGCCAGGCAAGAG AACCAGGAGGCAGAGCGGGAGGGTGGCATGAGCTGCAGCTGCAGCAGTGGCAGTGGTGAG GCCAGTGCTGGGCTGATGGAGGAGGCGCTGCCCTCTGCGCCCGAGCGCCTGGCCCTGGAC TATATCGTGCCCTGCATGCGGTACTACGGCATCTGCGTCAAGGACAGCTTCCTGGGGGCA GCACTGGGCGGTCGCGTGCTGGCCGAGGTGGAGGCCCTCAAACGGGGTGGGCGCCTGCGA GACGGGCAGCTAGTGAGCCAGAGGGCGATCCCGCCGCGCAGCATCCGTGGGGACCAGATT GCCTGGGTGGAAGGCCATGAACCAGGCTGTCGAAGCATTGGTGCCCTCATGGCCCATGTG GACGCCGTCATCCGCCACTGCGCAGGGCGGCTGGGCAGCTATGTCATCAACGGGCGCACC AAGGCCATGGTGGCGTGTTACCCAGGCAACGGGCTCGGGTACGTAAGGCACGTTGACAAT CCCCACGGCGATGGGCGCTGCATCACCTGTATCTATTACCTGAATCAGAACTGGGACGTT AAGGTGCATGGCGGCCTGCTGCAGATCTTCCCTGAGGGCCGGCCCGTGGTAGCCAACATC GAGCCACTCTTTGACCGGTTGCTCATTTTCTGGTCTGACCGGCGGAACCCCCACGAGGTG AAGCCAGCCTATGCCACCAGGTACGCCATCACTGTCTGGTATTTTGATGCCAAGGAGCGG GCAGCAGCCAAAGACAAGTATCAGCTAGCATCAGGACAGAAAGGTGTCCAAGTACCTGTA TCACAGCCGCCTACGCCCACCTAG Clone variation with respect to NM_053046.3 173 c=>t >OriGene 5' read for NM_053046 unedited
TAACCCCGCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCA GAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGA ATTCGGCACGAGGGCGGCTGGCACAAACGGCGGCGCCGGGGCCGGAGGAAAAAGCTCGCC ACCCTGAAGGGTCCCTTCCCAAGCCCTTAGGGACCGCAGAGGACTTGGGGACCAGCAAGC AACCCCCAGGGCACGAGAAGAGCTCTTGCTGTCTGCCCTGCCTCACCCTGCCCCACACCA GGCCCGGTGGCCCCCAGCTGCATCAAGTGGAGGCGGAGGAGGAGGCGGAGGAGGGTGGCA CCATGGGCCCGGGCGGTGCCCTCCATGCCCGGGGGATGAAGACACTGCTGCCATGGACAG CCCGTGCCAGCCGCAGCCCCTAAGTCAGGCTCTCCCTCAGTTACCAGGGTCTTCGTCAGA GCCCTTGGAGCCTGAGCCTGGCCGGGCCAGGATGGGAGTGGAGAGTTACCTGCCCTGTCC CCTGCTCCCCTCCTACCACTGTCCAGGAGTGCCTACTGAGGCCTTGGCAGGGAGTGGGAC CCCCAGAGCCACAGCCACCTCTACCACTGNCAGCCCTCTTCGGTACGGTNTTTGCGGACA GGATGGTGGTGAGCTGCNGTCGCTGCAAAGTGAAAGCGCTGCANNCGCTGTCACCCAAGG GTGCCAGCGATTGGCAGCCCAGGCGCACCGTCTGAGCCCCCAAACGGNAATGGCCCCAGA TGGTGGGGATGCCCTTTACCAGCAAACGGCCCTGGCCAGGCAGAGACCCAGAGGCAAACG GNAGGTGCATGACTGCACTGCACATGCACGGGGTAGCCATGCTGGCTATGGAGGAGGCTG CTTTTGCCAGACCCGGCCTGAAATATAAGGCTGCTGCGGCTAAGG >OriGene 3' read for NM_053046 unedited
CCCCCCTCCANNNAAATGGTGTGGAGTAAACTTTTTTGCTGGCTGACAGNACTCCCACCC ATGCTCCTCCTGGCACCTTTTACTCTGCCCAAGCAGTGGCAGCCCAGTCCAAAAGTGCCT GCCATGGCCAAAGGGGTTGGGGAGTCACTTCACATTCCAGGCTGGAGGAGTGAGAGGACT TGGGGGTACTCCTCCCACCCCATTGCCAGCAAGAGGCCATGTTTCACCTCAACCCCAAGT CCTGCATCCTGGTGGGAAGTGGACCATGCCTCCTTCCAGTTTTCCTTACCTAAGGGGGGA CATGACCAACCGGGGTAAGGAACCAGGCCCCCCAACTTCAATTTGGTAACGGGGGCCTTC AAGGTTGGCCCCCGTCCCGGGTAAAACCCCCCCCCCCATTAGGGGGGAAAAAAAGGGTCT TTTTCCCCCCTTGGGCCCCCAAAAAACAAAAAGAGCCCCCCCACCCCCGGGGGGGCCAGG GCCAATTTAAAACCCCCCCCCGGGGCGGGGGAAGGGGAATCCCCAAACCCCCGGGGTTCC TCAAAAAAATTTTAAAACTTTCTCCCCCCCCCTTTGGGGGCCGCCCCACAATTGGGGGCC AGGCCCCGGGGTTTTAAAAACAAATTTTTACACCCCTCTTTTCTGCGGGGGCGTTTCTAA ACAAACCCCCTTTTCTTTGTGGGTGGCCCCCCCCTTCTTTTCACCAAAAACAAACAACCA CCAAGGTGGGCCGGTTTCCCTGGGGGGCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_053046 |
| Insert Size | 1800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_053046.2, NP_444274.1 |
| RefSeq Size | 2111 bp |
| RefSeq ORF | 1224 bp |
| Locus ID | 112398 |
| UniProt ID | Q96KS0 |
| Protein Families | Druggable Genome |
| Protein Pathways | Pathways in cancer, Renal cell carcinoma |
| Gene Summary | The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011] Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Both variants 1 and 3 utilize alternative start codons that result in expression of two isoforms known as PHD1p43 and PHD1p40. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206152 | EGLN2 (Myc-DDK-tagged)-Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 1 |
CNY 3,656.00 |
|
| RC206152L1 | Lenti ORF clone of Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC206152L2 | Lenti ORF clone of Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC206152L3 | Lenti ORF clone of Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206152L4 | Lenti ORF clone of Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG206152 | EGLN2 (tGFP-tagged) - Human egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 1 |
CNY 5,256.00 |
