LILRB1 (NM_006669) Human Untagged Clone

CAT#: SC127469

LILRB1 (untagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1), transcript variant 1



  "NM_006669" in other vectors (6)

CNY 4,848.00

CNY 7,220.00


货期*
现货

规格
    • 10 ug

Cited in 2 publications.

Product images

经常一起买 (4)
Rabbit Polyclonal Anti-LILRB1 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CD85J; ILT-2; ILT2; LIR-1; LIR1; MIR-7; MIR7; PIR-B; PIRB
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC127469 sequence for NM_006669 edited (data generated by NextGen Sequencing)
ATGACCCCCATCCTCACGGTCCTGATCTGTCTCGGGCTGAGTCTGGGCCCCAGGACCCAC
GTGCAGGCAGGGCACCTCCCCAAGCCCACCCTCTGGGCTGAACCAGGCTCTGTGATCACC
CAGGGGAGTCCTGTGACCCTCAGGTGTCAGGGGGGCCAGGAGACCCAGGAGTACCGTCTA
TATAGAGAAAAGAAAACAGCACTCTGGATTACACGGATCCCACAGGAGCTTGTGAAGAAG
GGCCAGTTCCCCATCCCATCCATCACCTGGGAACATGCAGGGCGGTATCGCTGTTACTAT
GGTAGCGACACTGCAGGCCGCTCAGAGAGCAGTGACCCCCTGGAGCTGGTGGTGACAGGA
GCCTACATCAAACCCACCCTCTCAGCCCAGCCCAGCCCCGTGGTGAACTCAGGAGGGAAT
GTAATCCTCCAGTGTGACTCACAGGTGGCATTTGATGGCTTCAGTCTGTGTAAGGAAGGA
GAAGATGAACACCCACAATGCCTGAACTCCCAGCCCCATGCCCGTGGGTCGTCCCGCGCC
ATCTTCTCCGTGGGCCCCGTGAGCCCGAGTCGCAGGTGGTGGTACAGGTGCTATGCTTAT
GACTCGAACTCTCCCTATGAGTGGTCTCTACCCAGTGATCTCCTGGAGCTCCTGGTCCTA
GGTGTTTCTAAGAAGCCATCACTCTCAGTGCAGCCAGGTCCTATCGTGGCCCCTGAGGAG
ACCCTGACTCTGCAGTGTGGCTCTGATGCTGGCTACAACAGATTTGTTCTGTATAAGGAC
GGGGAACGTGACTTCCTTCAGCTCGCTGGCGCACAGCCCCAGGCTGGGCTCTCCCAGGCC
AACTTCACCCTGGGCCCTGTGAGCCGCTCCTACGGGGGCCAGTACAGATGCTACGGTGCA
CACAACCTCTCCTCCGAGTGGTCGGCCCCCAGTGACCCCCTGGACATCCTGATCGCAGGA
CAGTTCTATGACAGAGTCTCCCTCTCGGTGCAGCCGGGCCCCACGGTGGCCTCAGGAGAG
AACGTGACCCTGCTGTGTCAGTCACAGGGATGGATGCAAACTTTCCTTCTGACCAAGGAG
GGGGCAGCTGATGACCCATGGCGTCTAAGATCAACGTACCAATCTCAAAAATACCAGGCT
GAATTCCCCATGGGTCCTGTGACCTCAGCCCATGCGGGGACCTACAGGTGCTACGGCTCA
CAGAGCTCCAAACCCTACCTGCTGACTCACCCCAGTGACCCCCTGGAGCTCGTGGTCTCA
GGACCGTCTGGGGGCCCCAGCTCCCCGACAACAGGCCCCACCTCCACATCTGGCCCTGAG
GACCAGCCCCTCACCCCCACCGGGTCGGATCCCCAGAGTGGTCTGGGAAGGCACCTGGGG
GTTGTGATCGGCATCTTGGTGGCCGTCATCCTACTGCTCCTCCTCCTCCTCCTCCTCTTC
CTCATCCTCCGACATCGACGTCAGGGCAAACACTGGACATCGACCCAGAGAAAGGCTGAT
TTCCAACATCCTGCAGGGGCTGTGGGGCCAGAGCCCACAGACAGAGGCCTGCAGTGGAGG
TCCAGCCCAGCTGCCGATGCCCAGGAAGAAAACCTCTATGCTGCCGTGAAGCACACACAG
CCTGAGGATGGGGTGGAGATGGACACTCGGAGCCCACACGATGAAGACCCCCAGGCAGTG
ACGTATGCCGAGGTGAAACACTCCAGACCTAGGAGAGAAATGGCCTCTCCTCCTTCCCCA
CTGTCTGGGGAATTCCTGGACACAAAGGACAGACAGGCGGAAGAGGACAGGCAGATGGAC
ACTGAGGCTGCTGCATCTGAAGCCCCCCAGGATGTGACCTACGCCCAGCTGCACAGCTTG
ACCCTCAGACGGGAGGCAACTGAGCCTCCTCCATCCCAGGAAGGGCCCTCTCCAGCTGTG
CCCAGCATCTACGCCACTCTGGCCATCCACTAG

Clone variation with respect to NM_006669.3
933 c=>t
>OriGene 5' read for NM_006669 unedited
AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCACACGCAGCTCAGCCTGG
GCGGCACAGCCAGATGCGAGATGCGTCTCTGCTGATCTGAGTCTGCCTGCAGCATGGACC
TGGGTCTTCCCTGAAGCATCTCCAGGGCTGGAGGGACGACTGCCATGCACCGAGGGCTCA
TCCATCCACAGAGCAGGGCAGTGGGAGGAGACGCCATGACCCCCATCCTCACGGTCCTGA
TCTGTCTCGGGCTGAGTCTGGGCCCCAGGACCCACGTGCAGGCAGGGCACCTCCCCAAGC
CCACCCTCTGGGCTGAACCAGGCTCTGTGATCACCCAGGGGAGTCCTGTGACCCTCAGGT
GTCAGGGGGGCCAGGAGACCCAGGAGTACCGTCTATATAGAGAAAAGAAAACAGCACTCT
GGATTACACGGATCCCACAGGAGCTTGTGAAGAAGGGCCAGTTCCCCATCCCATCCATCA
CCTGNGAACATGCAGGGCGGTATCGCTGTTACTATGGTAGCGACACTGCAGGCCGCTCAG
AGAGCAGTGACCCCCTGGAGCTGGTGGTGACAGGAGCCTACATCAAACCCACCCTCTCAG
CCCAGCCCAGCCCCGTGGTGAACTCAGGAGGGAAATGTATCCTCCAGTGTGACTCACAGG
TGGGCATTGATGGCTTCAGTCTGTGTAAGGAAGGAGAAGATGAACCCCANCATGCCTGAA
CTCCCAGCCCATGCCCGTGGTCGTCCCGCGCCATCTTCTCCGTGGGCCCCGTGAGCCGAG
TCGCAGTGGTGGTACAGTGCTATGCTTATGACTCGAACTCTCCCTATGAGTGGGCTCTAC
CCATGATCTCCTGGAGCTCTGGTCCTAGGTTTTCTAAAGAGCCATACTCTCAGTGCAGCC
AGTTCTATCGGGCCN
>OriGene 3' read for NM_006669 unedited
TATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTCTTTCTTTTTT
TTTTTTTTTTTTAATTTGAGATGGAGTCTCCCTCTGTCGCCAGGCTGGAGAGCAGTGGTG
CGATCTTGGCTCACTGAAACCTCTGACTCCCTGGTTCAAGCGATTCTCCTGCCTCAGCCT
CCCAAATAGCTGGGATTACAGGCACTGCCACCACATCCAGCTAATTTTTGTATTTTTAGG
AGAGACAGGGTTTCACCATGTTGGCCAAGATGGTCTCGATCTCCTGAACTCGTGATCTGC
CCGCCTCGGCCTCCCAAAGTGCTGGAATTACAGGCGTGAGCCACCGTGCCCTGCCCTAAA
TTTCTTATAGGAAAGCCAAGATCATTCATTTCCTACTTTTTTTCTTTCCTAATTCATTCA
TTCGNGGCTTGTAGTTTTCCAGTTTCATCGCTTGATGTGTAATATTTACATTGCGATTCA
GTTTAATGCACTTTCTGACTTAGTTTTCTCAGCTACTTCATTGATTATTGAGAAGTCTGT
TGCTTTATTTCAAAATTGTAGAGACATTAGTTATTTATACTGCAGAATTGAGTGACCCCT
AAAAGTTCCCAGAGTCTCCTGGGGTAGACCCAGGCTGGGTGGGGTCCAATGGTGCCCACT
GGGGGGGCAGCTCCCATGCATTCCAGACTCCATGGAGTGTGGGGCCTGCGTCCCCCCCTG
GGCTAGTGGATGGCCAGAGTGGCGTAAATGCTGGGCACACGCTGGACAGGCCCCTTTCTG
GGATGGAGGAGGCTCAGTTTGCCTCCCGTCTGACGGTCAAGCTGTGCAGCCGGGCCGAAG
GCCCATTCCTGGGGGCCTTCAGATGCAGAAGCCTCAGGGGCCATCTGCCTGCCCTTCTCC
GCTGCCTGCCTGGTGCCCAGGACTCCCCCAACAGGGCGAAAGAGGAAAGCCATTCCCCCC
AGCCTGGGGGCCCACCCCGCACN
Restriction Sites NotI-NotI     
ACCN NM_006669
Insert Size 2880 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_006669.2, NP_006660.1
RefSeq Size 2984 bp
RefSeq ORF 1953 bp
Locus ID 10859
UniProt ID Q8NHL6
Domains ig, IGc2, IG
Protein Families Transmembrane
Gene Summary This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species and on the presence of a predicted signal peptide in the protein N-terminus. An upstream in-frame start codon is also present but is only conserved in primates, and use of the upstream start codon would result in a protein that is 17 aa longer at the N-terminus and lacks a predicted signal peptide. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)

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