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KPNA4 (NM_002268) Human Untagged Clone
CAT＃: SC127533
KPNA4 (untagged)-Human karyopherin alpha 4 (importin alpha 3) (KPNA4)
CNY 3,888.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IPOA3; QIP1; SRP3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127533 sequence for NM_002268 edited (data generated by NextGen Sequencing)
ATGGCGGACAACGAGAAACTGGACAACCAACGGCTCAAGAATTTCAAGAACAAAGGCCGC GACTTGGAGACTATGAGAAGACAACGAAATGAAGTTGTAGTTGAATTAAGGAAGAATAAA AGAGATGAACATCTCTTAAAGAGAAGGAATGTACCACATGAAGATATCTGTGAAGACTCT GATATAGATGGTGATTATAGAGTGCAAAATACCTCTCTAGAAGCTATTGTTCAAAATGCT TCAAGTGATAACCAAGGAATTCAATTAAGTGCAGTTCAAGCTGCTAGGAAGCTTTTGTCC AGTGATCGAAATCCACCAATTGATGACTTAATAAAATCTGGAATATTGCCCATTTTAGTC CATTGTCTTGAAAGAGATGACAATCCTTCTTTACAGTTTGAAGCTGCATGGGCTTTGACA AACATTGCATCTGGAACTTCTGAACAAACTCAAGCAGTAGTTCAGTCCAATGCTGTGCCA CTTTTCCTGAGGCTTCTCCATTCACCCCATCAGAATGTCTGTGAGCAAGCAGTGTGGGCA TTGGGAAATATCATAGGTGATGGGCCCCAGTGTAGAGATTATGTCATAAGTCTTGGAGTT GTGAAACCTTTACTTTCCTTCATAAGTCCATCTATTCCTATAACATTCTTAAGAAATGTT ACTTGGGTTATGGTCAACTTATGTCGCCACAAAGACCCACCACCACCAATGGAAACCATT CAGGAGATTCTTCCAGCCCTTTGTGTTTTAATTCATCACACAGATGTAAATATACTGGTA GACACAGTCTGGGCCCTCTCTTACCTTACTGATGCTGGCAATGAACAAATACAGATGGTA ATAGACTCTGGAATAGTTCCTCATTTGGTTCCTCTGCTCAGCCACCAGGAAGTTAAAGTT CAGACTGCTGCACTTAGAGCTGTGGGCAACATTGTTACTGGAACTGATGAGCAAACACAA GTAGTTTTGAACTGTGATGCTCTTTCACACTTCCCAGCACTCCTGACACATCCCAAAGAG AAAATTAATAAAGAAGCAGTGTGGTTCCTCTCCAACATCACTGCAGGAAATCAGCAGCAG GTACAGGCAGTAATTGATGCCAATCTTGTACCAATGATAATACACCTTTTGGATAAGGGG GATTTTGGCACTCAAAAAGAAGCTGCTTGGGCCATAAGTAACTTAACAATTAGTGGAAGG AAAGATCAAGTGGCTTACCTTATCCAACAAAATGTTATCCCACCTTTTTGCAACTTGCTG ACTGTAAAAGATGCACAAGTTGTGCAAGTAGTACTCGATGGACTAAGTAATATATTAAAA ATGGCTGAAGATGAGGCAGAAACCATAGGCAATCTTATAGAAGAATGTGGAGGGCTGGAG AAAATTGAACAACTTCAAAATCATGAAAATGAAGACATCTACAAATTGGCCTATGAGATC ATTGATCAGTTCTTCTCTTCAGATGATATTGATGAAGACCCTAGCCTTGTTCCAGAGGCA ATTCAAGGCGGAACATTTGGTTTCAATTCATCTGCCAATGTACCAACAGAAGGGTTCCAG TTTTAG Clone variation with respect to NM_002268.4 >OriGene 5' read for NM_002268 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGGCCCGGCCATGGCG GACAACGAGAAACTGGACAACCAACGGCTCAAGAATTTCAAGAACAAAGGCCGCGACTTG GAGACTATGAGAAGACAACGAAATGAAGTTGTAGTTGAATTAAGGAAGAATAAAAGAGAT GAACATCTCTTAAAGAGAAGGAATGTACCACATGAAGATATCTGTGAAGACTCTGATATA GATGGTGATTATAGAGTGCAAAATACCTCTCTAGAAGCTATTGTTCAAAATGCTTCAAGT GATAACCAAGGAATTCAATTAAGTGCAGTTCAAGCTGCTAGGAAGCTTTTGTCCAGTGAT CGAAATCCACCAATTGATGACTTAATAAAATCTGGAATATTGCCCATTTTAGTCCATTGT CTTGAAAGAGATGACAATCCTTCTTTACAGTTTGAAGCTGCATGGGCTTTGACAAACATT GCATCTGGAACTTCTGAACAAACTCAAGCAGTAGTTCAGTCCAATGCTGTGCCACTTTTC CTGAGGCTTCTCCATTCACCCCATCAGAATGTCTGTGAGCAAGCAGTGTGGGCATTGGGA AATATCATAGGTGATGGGCCCCAGTGTAGAGATTATGTCATAAGTCTTGGAGTTGTGAAA CCTTTACTNTCCTTCATAAGTCCATCTATTCCTATAACATTCTTAAGAATGTTACTTGGG TTATGGGTCACTTATGTCGCCCAAAGACCCACCACCACCAATGGGAACCATTCANGAGAT TCTTNCACCTTNNTGTGTTTAATNCATCACACAGATGTAAATATACTGGTAGACACAGTC TGGGCCCTCTCTTNACTTACTGATGCTGGCATGAACAATACAGATGGTATAGACC >OriGene 3' read for NM_002268 unedited
NTTTGCTCTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTGCTTTAAGTTTTAATGGTTATTTCCCCAAAACAACCTAACCTGCA CTCTACTTGGATAAATTTTACAAGCTAGTTTTCTGCTGCTTCTAATTTTAAACTTTAACC ATGTTTCTGATGACAAGGAATGCTGCAAAAATACTCTAGTTCAACAAAGAGTTATGATCA CCAAATAATTTTTATCCCTTCTACAGGGGTTCAAAATTACCAGTTGATTTTTAAACACAA AGTAGATATAGATGCTAATGGGGGCTAATCTGGGATGTTTCTTATAACAAACTGGTGTTC ATGCAACACTTGTGCTCAAAGGGGAAGGCACAGGATTTCCTACAATGAGCCACCTTATAA AGAGTTCTTTTTGTACAAATTAATTTATGTCACATTTAATTTAATGGGCATAACCTCAAA ACTGAGGGATTATTCCAATTTATAAAAACCACTTGCATAACTTTTATGCAAGTTTTAAAA ATACAAAGTTTTCTCCCTAAAGTGGCTCAAAATAAATTGGTCATGGCTGCCTACATCTAA GATAAAAAGATTCTAAAACAATTGAACAGATTAGGCCTATTATTAAAGGTGTTCAAACCA TTACTTGATTTGGACATCTACTCAAACCTCTTCATCGGTCTTTATTCAGCAGTACATATG CACCAAATTCCCATTTTAGAAGTTTCCATATCATTTTCATAGAAAACAAAGTTTGGAAAC CAGTAACATTTAAACACAGCACGGGATTNCTACACCACTGGAACTTTTTTCTTTCTCTTC TTTACAGGACTCAACAAAATCTAAATGAACTATGCTGTAAATTTACCTCCTGCAAAGATC TTTTAGTTATCTCTTGAAATGAAAGGAAAGGCTTTTAAGCACATTTTACTGTTTTTACCT TTTATGGCAACA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002268 |
| Insert Size | 4040 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002268.3, NP_002259.1 |
| RefSeq Size | 3816 bp |
| RefSeq ORF | 1566 bp |
| Locus ID | 3840 |
| UniProt ID | O00629 |
| Domains | Armadillo_seg, IBB |
| Gene Summary | The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Importin {alpha}3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication
,Zhujun Ao, Kallesh Danappa Jayappa, Binchen Wang, Yingfeng Zheng, Sam Kung, Eric Rassart, Reinhard Depping, Matthias Kohler, Eric A. Cohen, and Xiaojian Yao,
J. Virol., Sep 2010; 84: 8650 - 8663
[KPNA4]
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Prohibitin Inhibits Tumor Necrosis Factor alpha–induced Nuclear Factor-kappa B Nuclear Translocation via the Novel Mechanism of Decreasing Importin {alpha}3 Expression
,Arianne L. Theiss, Aaron K. Jenkins, Ngozi I. Okoro, Jan-Michael A. Klapproth, Didier Merlin, and Shanthi V. Sitaraman,
Mol. Biol. Cell, Oct 2009; 20: 4412 - 4423
[KPNA4]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205448 | KPNA4 (Myc-DDK-tagged)-Human karyopherin alpha 4 (importin alpha 3) (KPNA4) |
CNY 3,880.00 |
|
| RC205448L1 | Lenti ORF clone of Human karyopherin alpha 4 (importin alpha 3) (KPNA4), Myc-DDK-tagged |
CNY 6,280.00 |
|
| RC205448L2 | Lenti ORF clone of Human karyopherin alpha 4 (importin alpha 3) (KPNA4), mGFP tagged |
CNY 5,890.00 |
|
| RC205448L3 | Lenti ORF clone of Human karyopherin alpha 4 (importin alpha 3) (KPNA4), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205448L4 | Lenti ORF clone of Human karyopherin alpha 4 (importin alpha 3) (KPNA4), mGFP tagged |
CNY 5,890.00 |
|
| RG205448 | KPNA4 (tGFP-tagged) - Human karyopherin alpha 4 (importin alpha 3) (KPNA4) |
CNY 5,480.00 |
