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SEMA4A (NM_022367) Human Untagged Clone
CAT＃: SC128157
SEMA4A (untagged)-Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (SEMA4A), transcript variant 1
CNY 5,584.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CORD10; RP35; SEMAB; SEMB |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128157 sequence for NM_022367 edited (data generated by NextGen Sequencing)
ATGGCCCTCCCAGCCCTGGGCCTGGACCCCTGGAGCCTCCTGGGCCTTTTCCTCTTCCAA CTGCTTCAGCTGCTGCTGCCGACGACGACCGCGGGGGGAGGCGGGCAGGGGCCCATGCCC AGGGTCAGATACTATGCAGGGGATGAACGTAGGGCACTTAGCTTCTTCCACCAGAAGGGC CTCCAGGATTTTGACACTCTGCTCCTGAGTGGTGATGGAAATACTCTCTACGTGGGGGCT CGAGAAGCCATTCTGGCCTTGGATATCCAGGATCCAGGGGTCCCCAGGCTAAAGAACATG ATACCGTGGCCAGCCAGTGACAGAAAAAAGAGTGAATGTGCCTTTAAGAAGAAGAGCAAT GAGACACAGTGTTTCAACTTCATCCGTGTCCTGGTTTCTTACAATGTCACCCATCTCTAC ACCTGCGGCACCTTCGCCTTCAGCCCTGCTTGTACCTTCATTGAACTTCAAGATTCCTAC CTGTTGCCCATCTCGGAGGACAAGGTCATGGAGGGAAAAGGCCAAAGCCCCTTTGACCCC GCTCACAAGCATACGGCTGTCTTGGTGGATGGGATGCTCTATTCTGGTACTATGAACAAC TTCCTGGGCAGTGAGCCCATCCTGATGCGCACACTGGGATCCCAGCCTGTCCTCAAGACC GACAACTTCCTCCGCTGGCTGCATCATGACGCCTCCTTTGTGGCAGCCATCCCTTCGACC CAGGTCGTCTACTTCTTCTTCGAGGAGACAGCCAGCGAGTTTGACTTCTTTGAGAGGCTC CACACATCGCGGGTGGCTAGAGTCTGCAAGAATGACGTGGGCGGCGAAAAGCTGCTGCAG AAGAAGTGGACCACCTTCCTGAAGGCCCAGCTGCTCTGCACCCAGCCGGGGCAGCTGCCC TTCAACGTCATCCGCCACGCGGTCCTGCTCCCCGCCGATTCTCCCACAGCTCCCCACATC TACGCAGTCTTCACCTCCCAGTGGCAGGTTGGCGGGACCAGGAGCTCTGCGGTTTGTGCC TTCTCTCTCTTGGACATTGAACGTGTCTTTAAGGGGAAATACAAAGAGTTGAACAAAGAA ACTTCACGCTGGACTACTTATAGGGGCCCTGAGACCAACCCCCGGCCAGGCAGTTGCTCA GTGGGCCCCTCCTCTGATAAGGCCCTGACCTTCATGAAGGACCATTTCCTGATGGATGAG CAAGTGGTGGGGACGCCCCTGCTGGTGAAATCTGGCGTGGAGTATACACGGCTTGCAGTG GAGACAGCCCAGGGCCTTGATGGGCACAGCCATCTTGTCATGTACCTGGGAACCACCACA GGGTCGCTCCACAAGGCTGTGGTAAGTGGGGACAGCAGTGCTCATCTGGTGGAAGAGATT CAGCTGTTCCCTGACCCTGAACCTGTTCGCAACCTGCAGCTGGCCCCCACCCAGGGTGCA GTGTTTGTAGGCTTCTCAGGAGGTGTCTGGAGGGTGCCCCGAGCCAACTGTAGTGTCTAT GAGAGCTGTGTGGACTGTGTCCTTGCCCGGGACCCCCACTGTGCCTGGGACCCTGAGTCC CGAACCTGTTGCCTCCTGTCTGCCCCCAACCTGAACTCCTGGAAGCAGGACATGGAGCGG GGGAACCCAGAGTGGGCATGTGCCAGTGGCCCCATGAGCAGGAGCCTTCGGCCTCAGAGC CGCCCGCAAATCATTAAAGAAGTCCTGGCTGTCCCTAACTCCATCCTGGAGCTCCCCTGC CCCCACCTGTCAGCCTTGGCCTCTTATTATTGGAGTCATGGCCCAGCAGCAGTCCCAGAA GCCTCTTCCACTGTCTACAATGGCTCCCTCTTGCTGATAGTGCAGGATGGAGTTGGGGGT CTCTACCAGTGCTGGGCAACTGAGAATGGCTTTTCATACCCTGTGATCTCCTACTGGGTG GACAGCCAGGACCAGACCCTGGCCCTGGATCCTGAACTGGCAGGCATCCCCCGGGAGCAT GTGAAGGTCCCGTTGACCAGGGTCAGTGGTGGGGCCGCCCTGGCTGCCCAGCAGTCCTAC TGGCCCCACTTTGTCACTGTCACTGTCCTCTTTGCCTTAGTGCTTTCAGGAGCCCTCATC ATCCTCGTGGCCTCCCCATTGAGAGCACTCCGGGCTCGGGGCAAGGTTCAGGGCTGTGAG ACCCTGCGCCCTGGGGAGAAGGCCCCGTTAAGCAGAGAGCAACACCTCCAGTCTCCCAAG GAATGCAGGACCTCTGCCAGTGATGTGGACGCTGACAACAACTGCCTAGGCACTGAGGTA GCTTAA Clone variation with respect to NM_022367.3 1716 c=>t >OriGene 5' read for NM_022367 unedited
TGTATACGACTCATATAGGCGGCCGCGAATTCGGCACGAGGCTGGCTTTGGCATGATGGG CACCTGGAGGGCCGCACTCCCGTTCCAGCCAGGCTGAGCCTTCTGTCCCCTGCCTCTGGG GCCTGGGAACCCCCCTTCTTCTTTCTCCTGAATGGCACCCCCGCCCTAGAATCCAGACAC CGAGTTTCCCACTGTGGCTGGTTCAAGGAGCTCCCTGGTGACAGTCTGTGGCTGAGCATG GCCCTCCCAGCCCTGGGCCTGGACCCCTGGAGCCTTCTGGGCCTTTTCCTCTCCCAACTG CTTCAGCTGCTGCTGCCGACGACCACCGCGGGGGGAGGCGGGCAGGGGCCCATGCCCAGG GCCATATACTATGCAGGGGATGAACGTACGGCACTTAGCTTCTTCCACCAGAAGGGCCTC CAGGATTTTGACACTCTGCTCCTGAGTGGNGACGGAAATACTCTCTACGTGGGGGCTCGA GAAGCCATTCTGGCCTTGGATATCCCCCATCCCAGGGGTCCCCAGGCTAAAGAACATGAT ACCGTGGCCAGCCCGTGACCGAAAAAAGAGCGAATGCGCCTTTAACACGAAAGCAATGAG AACACAGGTTTCACTCCATCCGCGTCCTGGCTTTCTTACAATGTCACCCATCTCTACACC CTGCGGAACCTTCCCCCTTAACCCTGCTTGCCCCCTTCTTGAAATTCCCGACTCCTACCT GGTGCCCACCTTGCAGACAATGTCACTGCGGCGAAAAGCCCAAACCCCTTTGCCCCGTTC CCAACCTACGGCTTGTCTCGTGGAGTGCGAGGCCCTTTTTGGGATACGAAAAATTCCTTG GCAGTGCGCCCTTCTGATGCCACACTGGGACCCACTCTGTCCTAAACCGCCACCTTCTCC CTGGCTCGATATGAACCCCCTTGGGGCAGACTCCCT >OriGene 3' read for NM_022367 unedited
TANGATCCGGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAACCCTTATATTTTT AATAAAAAATAAACAGTCTCTGACAAGCAGTTTTCTGAATCCCAAAACAAAGGAAAAGGG AGGGGGAGAGGTGAAGGGGTCAGCTAGGGTAAAGGAGTGAAGAAGGCTCAGATTACCCCT GCCATTCTGCCAGGGCAGAAGGGATCAGAGTCTGCCCCAACTGAAGCAAGAAGAAAGGTG GTCAGACTTCAGGGAAGACTTCCTGGGAGTCAGCGGTGCACGACTGGTAAGGGAAGCAGG AGGGAGCAGATCCCTGCATGACCCTGGGAGAAGGGAGTGTTGGTGTCCAAAGCGGCAGCT TCAGAGTGGAGTTTCCAGGAGTGGCATGTTAGCATATGATTGTTTAGATGTTTGGTGTTC ATTACCATAGGGTCCTGGGACAGGCAGGTTTTTTAGGGTCTCTTGAAACACTGTGTTTCT GGAGGGTCCCTGGAATGGCCAGAACTGAAGGATCCTCTCCAGGTTCTTCAATATCAGTGT AGGAGCAGGTCTGGGGGTAGCCCCCACCCTGTTAGAGAGCTCATGTGCTTGGTAGAAGGG AGTCCCATAGGGGAGGCAGACTGCTGTGCATCACCCTGCTGAGTGTCATCAGTGATGCAG AGTAGCAGAAGCTCCTCTCAGGGGAGAAAGGTGGTCTTTTGTGCTGCTGTCATCCTAGTC AGGGCTGGGCTTGGCCCGCCCAGCCAGCATGGCCAGGTGCCTGGACCGGAACCCCGGCCT GGGCCTAGAAGTTTAGCTACCCCAGTGCCTAAGCCGTTGGTGTCAGCGTCCACATCACTG GCAGAAGTCCTGGCATCTTTGGAGACTGGG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_022367 |
| Insert Size | 3900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022367.2, NP_071762.2 |
| RefSeq Size | 3257 bp |
| RefSeq ORF | 2286 bp |
| Locus ID | 64218 |
| UniProt ID | Q9H3S1 |
| Domains | Sema, PSI, PSI |
| Protein Families | Transmembrane |
| Protein Pathways | Axon guidance |
| Gene Summary | This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010] Transcript Variant: This variant (1) is the longest transcript. Variants 1-3 encode the same isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202231 | SEMA4A (Myc-DDK-tagged)-Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (SEMA4A), transcript variant 1 |
CNY 5,576.00 |
|
| RC202231L1 | Lenti ORF clone of Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (SEMA4A), transcript variant 1, Myc-DDK-tagged |
CNY 7,976.00 |
|
| RC202231L2 | Lenti ORF clone of Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (SEMA4A), transcript variant 1, mGFP tagged |
CNY 7,700.00 |
|
| RC202231L3 | Lenti ORF clone of Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (SEMA4A), transcript variant 1, Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC202231L4 | Lenti ORF clone of Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (SEMA4A), transcript variant 1, mGFP tagged |
CNY 7,976.00 |
|
| RG202231 | SEMA4A (tGFP-tagged) - Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (SEMA4A), transcript variant 1 |
CNY 7,176.00 |
|
| SC323738 | SEMA4A (untagged)-Human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (SEMA4A), transcript variant 1 |
CNY 5,584.00 |
