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CD32B (FCGR2B) (NM_004001) Human Untagged Clone
CAT＃: SC128159
FCGR2B (untagged)-Human Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 1
CNY 3,600.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD32; CD32B; FCG2; FCGR2; FCGR2C; FcRII-c; IGFR2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_004001, the custom clone sequence may differ by one or more nucleotides
ATGGGAATCCTGTCATTCTTACCTGTCCTTGCCACTGAGAGTGACTGGGCTGACTGCAAGTCCCCCCAGC CTTGGGGTCATATGCTTCTGTGGACAGCTGTGCTATTCCTGGCTCCTGTTGCTGGGACACCTGCAGCTCC CCCAAAGGCTGTGCTGAAACTCGAGCCCCAGTGGATCAACGTGCTCCAGGAGGACTCTGTGACTCTGACA TGCCGGGGGACTCACAGCCCTGAGAGCGACTCCATTCAGTGGTTCCACAATGGGAATCTCATTCCCACCC ACACGCAGCCCAGCTACAGGTTCAAGGCCAACAACAATGACAGCGGGGAGTACACGTGCCAGACTGGCCA GACCAGCCTCAGCGACCCTGTGCATCTGACTGTGCTTTCTGAGTGGCTGGTGCTCCAGACCCCTCACCTG GAGTTCCAGGAGGGAGAAACCATCGTGCTGAGGTGCCACAGCTGGAAGGACAAGCCTCTGGTCAAGGTCA CATTCTTCCAGAATGGAAAATCCAAGAAATTTTCCCGTTCGGATCCCAACTTCTCCATCCCACAAGCAAA CCACAGTCACAGTGGTGATTACCACTGCACAGGAAACATAGGCTACACGCTGTACTCATCCAAGCCTGTG ACCATCACTGTCCAAGCTCCCAGCTCTTCACCGATGGGGATCATTGTGGCTGTGGTCACTGGGATTGCTG TAGCGGCCATTGTTGCTGCTGTAGTGGCCTTGATCTACTGCAGGAAAAAGCGGATTTCAGCTCTCCCAGG ATACCCTGAGTGCAGGGAAATGGGAGAGACCCTCCCTGAGAAACCAGCCAATCCCACTAATCCTGATGAG GCTGACAAAGTTGGGGCTGAGAACACAATCACCTATTCACTTCTCATGCACCCGGATGCTCTGGAAGAGC CTGATGACCAGAACCGTATTTAG >OriGene 5' read for NM_004001 unedited
CAGTCAGATTTGTATACCATCACTATAGGCGGCCGCGATTCCCGGGATCTGCTGTGCTCT GGGCGCCAGCTCGCTCCAGGAGTGATGGGAATCCTGTCATTCTTACCTGTCCTTGCCACT GAGAGTGACTGGGCTGACTGCAAGTCCCCCCAGCCTTGGGGTCATATGCTTCTGTGGACA GCTGTGCTATTCCTGGCTCCTGTTGCTGGGACACCTGCAGCTCCCCCAAGGCTGTGCTGA AACTCGAGCCCCAGTGGATCAACGTGCTCCAGGAGGACTCTGTGACTCTGACATGCCGGG GGACTCACAGCCCTGAGAGCGACTCCATTCAGTGGTTCCACAATGGGAATCTCATTCCCA CCCACACGCAGCCCAGCTACAGGTTCAAGGCCAACAACAATGACAGCGGGGAGTACACGT GCCAGACTGGCCAGACCAGCCTCAGCGACCCTGTGCATCTGACTGTGCTTTCTGAGTGGC TGGTGCTCCAGACCCCTCACCTGGAGTTCCAGGAGGGAGAAACCATCGTGCTGAGGTGCC ACAGCTGGAAAGACAAGCCTCTGGTCAAGGTCACATTCTTCCAGAATGGAAAATCCAAGA AATTTTCCCGTTCGGATCCCAACTTCTCCATCCCACAAGCAAACCACAGTCACAGTGGTG ATTACCACTGCACAGGTAACATATGCTACACGCTGGACTCATCCAAGCCTGGGACCATCA CTGTCCAAGCTCCCCAGCTCTCACCGGTGGGGATCATTGGGGCTGTGGGCACTGGGATTG CCTGTAACGCCAATGGTGCCGCCTGAATGGCCCTTGTCCACTGGAGGGAAAAACCGGATT TAACTTCTCCAAGATAACCCGGGGTCCGGGACAAGGGAGAAACCCTTCCCGGGGAAACCA GCCAATCCCACT >OriGene 3' read for NM_004001 unedited
NNNNNAAAACTTTGGACGCGGNCCGCCCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAATTGGGTTTAAAAAGGGTTTA TTAAAAAAGGAATATTTGGTCTTTTTTGAAAAATAAAGAAAATAAAAATCCTCCATAATT TTTTCCCCCCGAAACAATCACTTTTAAGGGGCGGGGAGGGGGTAGTCTATTTTAACATTT CTGAAATCATATAGATTTACCGGGTGGGTCTCACGGAACCGGGAACAAAAGCCTTTCCCA AGGGGGTATTATCGGGTAAAAACAGGGGGTTGGTTAAATGGATTGGCTGGGGGGGTGGGG AACGGAAAAACCTTGGTGTCAAAAAAAGCTGGAGCCCAAAAGGGGCCGTCGGGCATTTGG GGCCCTATTGGCTGGGGGTTTCAGGGCAGGGGGCTTCAGGGCCCAGGGAGATGACTCTGG GAAAAACCTTCTTTTTTGGAACTGGAGGATTTCCCTGGCCTCCCCAGGGGGATTTAGGGC CGGGAATACCCGATCTTCCCCCTTTGGTTTTCTTCTCAAAACCCAATGGCAGACAAGGGG GACTAAATACGGGTTTGGGCATTAGGGTTTTCCAAAGCATCCGGGGGCCTGAAAAGGGAA TAGGGGATTGGGGTCTCAGCCCCCACTTTGGCAGCCTCATCAGGATTAAGGGGGATGGCT GGGTTCTCAGGGAGGGGGCTCTCCATTTCCCCGGGCTAGGGGGACCCGGGGGAGCTGGAA ACCCCCTTTTCCTGGGGAAGAACAAGGGCCCCTACGGGGGAACAAGGGGGCGCTTAAAGG AAACCCGGGGGCCACCGGCCCCAAGGGCCCCCCTCGG |
| Restriction Sites | Please inquire |
| ACCN | NM_004001 |
| Insert Size | 1600 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004001.3, NP_003992.3 |
| RefSeq Size | 1633 bp |
| RefSeq ORF | 933 bp |
| Locus ID | 2213 |
| UniProt ID | P31994 |
| Domains | ig, IGc2, IG |
| Protein Families | ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus |
| Gene Summary | The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Human Fc{gamma}RII Cytoplasmic Domains Differentially Influence Antibody-Mediated Dengue Virus Infection
,Kobporn Boonnak, Bonnie M. Slike, Gina C. Donofrio, and Mary A. Marovich,
J. Immunol., Jun 2013; 190: 5659 - 5665.
,PubMed ID 23616574
[FCGR2B]
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|
Anti-Peptidoglycan Antibodies and Fc Receptors Are the Key Mediators of Inflammation in Gram-Positive Sepsis
,Dawei Sun, Brent Raisley, Marybeth Langer, Janaki K. Iyer, Vidya Vedham, Jimmy L. Ballard, Judith A. James, Jordan Metcalf, and K. Mark Coggeshall,
J. Immunol., Sep 2012; 189: 2423 - 2431.
[FCGR2B]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211982 | FCGR2B (Myc-DDK-tagged)-Human Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 1 |
CNY 3,600.00 |
|
| RC211982L1 | Lenti ORF clone of Human Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC211982L2 | Lenti ORF clone of Human Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 1, mGFP tagged |
CNY 6,000.00 |
|
| RC211982L3 | Lenti ORF clone of Human Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC211982L4 | Lenti ORF clone of Human Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 1, mGFP tagged |
CNY 6,000.00 |
|
| RG211982 | FCGR2B (tGFP-tagged) - Human Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 1 |
CNY 5,200.00 |
