gamma Sarcoglycan (SGCG) (NM_000231) Human Untagged Clone
CAT#: SC300030
SGCG (untagged)-Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG)
CNY 6,270.00
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | 35DAG; A4; DAGA4; DMDA; DMDA1; gamma-SG; LGMD2C; LGMDR5; MAM; SCARMD2; SCG3 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC300030 representing NM_000231.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGTGCGTGAGCAGTACACTACAGCCACAGAAGGCATCTGCATAGAGAGGCCAGAGAATCAGTATGTC TACAAAATTGGCATTTATGGCTGGAGAAAGCGCTGTCTCTACTTGTTTGTTCTTCTTTTACTCATCATC CTCGTTGTGAATTTAGCTCTTACAATTTGGATTCTTAAAGTGATGTGGTTTTCTCCAGCAGGAATGGGC CACTTGTGTGTAACAAAAGATGGACTGCGCTTGGAAGGGGAATCAGAATTTTTATTCCCATTGTATGCC AAAGAAATACACTCCAGAGTGGACTCATCTCTGCTTCTACAATCAACCCAGAATGTGACTGTAAATGCG CGCAACTCAGAAGGGGAGGTCACAGGCAGGTTAAAAGTCGGTCCCAAAATGGTAGAAGTCCAGAATCAA CAGTTTCAGATCAACTCCAACGACGGCAAGCCACTATTTACTGTAGATGAGAAGGAAGTTGTGGTTGGT ACAGATAAACTTCGAGTAACTGGGCCTGAAGGGGCTCTTTTTGAACATTCAGTGGAGACACCCCTTGTC AGAGCCGACCCGTTTCAAGACCTTAGATTAGAATCCCCCACTCGGAGTCTAAGCATGGATGCCCCAAGG GGTGTGCATATTCAAGCTCACGCTGGGAAAATTGAGGCGCTTTCTCAAATGGATATTCTTTTTCATAGT AGTGATGGAATGCTTGTGCTTGATGCTGAAACTGTGTGCTTACCCAAGCTGGTGCAGGGGACGTGGGGT CCCTCTGGCAGCTCACAGAGCCTCTACGAAATCTGTGTGTGTCCAGATGGGAAGCTGTACCTGTCTGTG GCCGGTGTGAGCACCACGTGCCAGGAGCACAGCCACATCTGCCTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_000231 |
Insert Size | 876 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_000231.2 |
RefSeq Size | 1661 bp |
RefSeq ORF | 876 bp |
Locus ID | 6445 |
UniProt ID | Q13326 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis |
MW | 32.4 kDa |
Gene Summary | This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC220093 | SGCG (Myc-DDK-tagged)-Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG) |
CNY 2,400.00 |
|
RC220093L3 | Lenti ORF clone of Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC220093L4 | Lenti ORF clone of Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG), mGFP tagged |
CNY 5,890.00 |
|
RG220093 | SGCG (tGFP-tagged) - Human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG) |
CNY 4,000.00 |
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