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CXCR4 (NM_001008540) Human Untagged Clone
CAT＃: SC301321
CXCR4 (untagged)-Human chemokine (C-X-C motif) receptor 4 (CXCR4), transcript variant 1
CNY 3,656.00
CNY 5,800.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001008540 edited
ATGTCCATTCCTTTGCCTCTTTTGCAGATATACACTTCAGATAACTACACCGAGGAAATG GGCTCAGGGGACTATGACTCCATGAAGGAACCCTGTTTCCGTGAAGAAAATGCTAATTTC AATAAAATCTTCCTGCCCACCATCTACTCCATCATCTTCTTAACTGGCATTGTGGGCAAT GGATTGGTCATCCTGGTCATGGGTTACCAGAAGAAACTGAGAAGCATGACGGACAAGTAC AGGCTGCACCTGTCAGTGGCCGACCTCCTCTTTGTCATCACGCTTCCCTTCTGGGCAGTT GATGCCGTGGCAAACTGGTACTTTGGGAACTTCCTATGCAAGGCAGTCCATGTCATCTAC ACAGTCAACCTCTACAGCAGTGTCCTCATCCTGGCCTTCATCAGTCTGGACCGCTACCTG GCCATCGTCCACGCCACCAACAGTCAGAGGCCAAGGAAGCTGTTGGCTGAAAAGGTGGTC TATGTTGGCGTCTGGATCCCTGCCCTCCTGCTGACTATTCCCGACTTCATCTTTGCCAAC GTCAGTGAGGCAGATGACAGATATATCTGTGACCGCTTCTACCCCAATGACTTGTGGGTG GTTGTGTTCCAGTTTCAGCACATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTG TCCTGCTATTGCATTATCATCTCCAAGCTGTCACACTCCAAGGGCCACCAGAAGCGCAAG GCCCTCAAGACCACAGTCATCCTCATCCTGGCTTTCTTCGCCTGTTGGCTGCCTTACTAC ATTGGGATCAGCATCGACTCCTTCATCCTCCTGGAAATCATCAAGCAAGGGTGTGAGTTT GAGAACACTGTGCACAAGTGGATTTCCATCACCGAGGCCCTAGCTTTCTTCCACTGTTGT CTGAACCCCATCCTCTATGCTTTCCTTGGAGCCAAATTTAAAACCTCTGCCCAGCACGCA CTCACCTCTGTGAGCAGAGGGTCCAGCCTCAAGATCCTCTCCAAAGGAAAGCGAGGTGGA CATTCATCTGTTTCCACTGAGTCTGAGTCTTCAAGTTTTCACTCCAGCTAACACAGATGT AAAAGACTTTTTTTTATACGATAAATAACTTTTTTTTAAGTTACACATTTTTCAGATATA AAAGACTGACCAATATTGTACAGTTTTTATTGCTTGTTGGATTTTTGTCTTGTGTTTCTT TAGTTTTTGTGAAGTTTAATTGACTTATTTATATAAATTTTTTTTGTTTCATATTGATGT GTGTCTAGGCAGGACCTGTGGCCAAGTTCTTAGTTGCTGTATGTCTCGTGGTAGGACTGT AGAAAAGGGAACTGAACATTCCAGAGCGTGTAGTGAATCACGTAAAGCTAGAAATGATCC CCAGCTGTTTATGCATAGATAATCTCTCCATTCCCGTGGAACGTTTTTCCTGTTCTTAAG ACGTGATTTTGCTGTAGAAGATGGCACTTATAACCAAAGCCCAAAGTGGTATAGAAATGC TGGTTTTTCAGTTTTCAGGAGTGGGTTGATTTCAGCACCTACAGTGTACAGTCTTGTATT AAGTTGTTAATAAAAGTACATGTTAAACTTAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001008540 unedited
NGAGTCAGATTTGTATACCATCACTATAGGCGGCCGCGAATTCGCACGAGGATGTCCATT CCTTTGCCTCTTTTGCAGATATACACTTCAGATAACTACACCGAGGAAATGGGCTCAGGG GACTATGACTCCATGAAGGAACCCTGTTTCCGTGAAGAAAATGCTAATTTCAATAAAATC TTCCTGCCCACCATCTACTCCATCATCTTCTTAACTGGCATTGTGGGCAATGGATTGGTC ATCCTGGTCATGGGTTACCAGAAGAAACTGAGAAGCATGACGGACAAGTACAGGCTGCAC CTGTCAGTGGCCGACCTCCTCTTTGTCATCACGCTTCCCTTCTGGGCAGTTGATGCCGTG GCAAACTGGTACTTTGGGAACTTCCTATGCAAGGCAGTCCATGTCATCTACACAGTCAAC CTCTACAGCAGTGTCCTCATCCTGGCCTTCATCAGTCTGGACCGCTACCTGGCCATCGTC CACGCCACCAACAGTCAGAGGCCAAGGAAGCTGTTGGCTGAAAAGGTGGTCTATGTTGGC GTCTGGATCCCTGCCCTCCTGCTGACTATTCCCGACTTCATCTTTGCCAACGTCAGTGAG GCAGATGACAGATATATCTGTGACCGCTTCTACCCCAATGACTTGTGGGTGGTTGTGTTT CAGTTTCAGCACATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTGTCCTGCTAT TGCATTATCATCTCCAAGCTGTCACACTCCCAAGGCCACCAGAAGCGCCAGGCCCCTCAA ACCACAGTCATCCTCATCCTGGNCTTCTTCGCCTGTTGGCTGCCTTACTACNTTGGGATC AGCATCGACTCCTTCATCCTNCTGGAAATCATCAAGCAGGGTGTGAGTTTGAGACACTG >Forward primer walk for NM_001008540 unedited
AATGAAGCAATATCTGTGACCGCTTCTACCCCATGACTTGTGGGTGGTTGTGTTCCAGTT TCAGCACATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTGTCCTGCTATTGCAT TATCATCTCCAAGCTGTCACACTCCAAGGGCCACCAGAAGCGCAAGGCCCTCAAGACCAC AGTCATCCTCATCCTGGCTTTCTTCGCCTGTTGGCTGCCTTACTACATTGGGATCAGCAT CGACTCCTTCATCCTCCTGAAAATCATCAAGCAAGGGTGTGAGTTTGAGAACACTGTGCA CAAGTGGATTTCCATCACCGAGGCCCTAGCTTTCTTCCACTGTTGTCTGAACCCCATCCT CTATGCTTTCCTTGGAGCCAAATTTAAAACCTCTGCCCAGCACGCACTCACCTCTGTGAG CAGAGGGTCCAGCCTCAAGATCCTCTCCAAAGGAAAGCGAGGTGGACATTCATCTGTTTC CACTGAACTCTGAGTCTTCAAGTTTTCACTCCAGCTAACACAGATGTAAACAAATTTTTT TTAATCGAAAAATAACCTTTTTTGTAAGAAAAACATTTCCGAAACCCAAACCACGGCCGA GTATAGACACGATTACAACGGGCGAAAGAACACAGAACAAAAGACCACCAAAAGAACGAA AAAGGGAAAAACACCAACAGTAGAAAAAAGCAGCCCCCAACAACAAAAAAAACACAACGA CCCCGACCACCGAAAGCAAACCAACAAAACCAAGGAAGGCGAAAAACCCACCCCACAAAA AGTACACTAATTAAGAAACACCCACCCCACCACACCCC |
| Restriction Sites | Please inquire |
| ACCN | NM_001008540 |
| Insert Size | 1600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001008540.1, NP_001008540.1 |
| RefSeq Size | 1912 bp |
| RefSeq ORF | 1071 bp |
| Locus ID | 7852 |
| UniProt ID | P61073 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane |
| Protein Pathways | Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Leukocyte transendothelial migration |
| Gene Summary | This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1), also known as CXCR4-Lo, differs in the 5' UTR and coding sequence compared to variant 3. The resulting isoform (a) has a shorter and distinct N-terminus compared to isoform c. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Hormophysa triquerta polyphenol, an elixir that deters CXCR4- and COX2-dependent dissemination destiny of treatment-resistant pancreatic cancer cells
,Aravindan, S;Ramraj, S;Kandasamy, K;Thirugnanasambandan, SS;Somasundaram, DB;Herman, TS;Aravindan, N;,
Oncotarget
,PubMed ID 27974694
[CXCR4]
|
|
Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation
,H D Park, Y Lee, Y K Oh, J G Jung, Y W Park, K Myung, K-H Kim, S S Koh, D-S Lim,
Oncogene (30 August 2010) doi:10.1038/onc.2010.401 Original Article
[CXCR4]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214548 | CXCR4 (Myc-DDK-tagged)-Human chemokine (C-X-C motif) receptor 4 (CXCR4), transcript variant 1 |
CNY 5,488.00 |
|
| RC214548L1 | Lenti ORF clone of Human chemokine (C-X-C motif) receptor 4 (CXCR4), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC214548L2 | Lenti ORF clone of Human chemokine (C-X-C motif) receptor 4 (CXCR4), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RC214548L3 | Lenti ORF clone of Human chemokine (C-X-C motif) receptor 4 (CXCR4), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC214548L4 | Lenti ORF clone of Human chemokine (C-X-C motif) receptor 4 (CXCR4), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RG214548 | CXCR4 (tGFP-tagged) - Human chemokine (C-X-C motif) receptor 4 (CXCR4), transcript variant 1 |
CNY 7,088.00 |
