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AZI1 (CEP131) (NM_001009811) Human Untagged Clone
CAT＃: SC301424
AZI1 (untagged)-Human 5-azacytidine induced 1 (AZI1), transcript variant 2
CNY 20,140.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AZ1; AZI1; ZA1 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001009811, the custom clone sequence may differ by one or more nucleotides
ATGAAAGGCACCCGGGCCATCGGCAGCGTCCCGGAGCGCAGCCCAGCAGGTGTGGACCTG AGTCTGACAGGTCTCCCTCCGCCTGTGTCCCGGCGTCCTGGCAGTGCCGCCACCACCAAG CCCATCGTCCGCTCTGTCTCCGTGGTCACAGGCAGCGAGCAGAAGAGGAAGGTGCTGGAG GCCACAGGGCCTGGGGGCTCCCAGGCCATCAACAACCTTAGAAGATCCAACAGCACCACG CAGGTCAGCCAGCCTCGGAGCGGCTCCCCCAGGCCAACGGAGCCCACAGACTTCCTGATG CTCTTCGAGGGCAGCCCCAGTGGGAAAAAGAGGCCTGCCAGCCTGAGCACAGCCCCCAGC GAGAAGGGAGCCACCTGGAACGTCCTGGATGACCAGCCCCGGGGCTTCACCTTGCCATCC AATGCCCGGAGTTCCAGTGCCCTTGACTCACCAGCGGGCCCGCGGAGGAAAGAATGCACC GTGGCCCTGGCCCCCAACTTCACTGCTAACAACAGGAGCAACAAGGGAGCAGTGGGCAAC TGCGTCACCACCATGGTGCACAACCGCTACACCCCCTCGGAGAGGGCGCCTCCGCTCAAG AGCTCCAACCAGACTGCCCCCTCCCTCAACAACATCATCAAGGCAGCCACCTGTGAGGGC AGTGAGAGCAGCGGCTTTGGGAAGCTGCCGAAGAATGTCTCCAGTGCCACCCACTCAGCC CGGAACAATACTGGGGGCAGCACGGGCTTGCCCAGGCGGAAGGAGGTGACGGAGGAGGAG GCTGAGAGGTTTATCCACCAGGTGAACCAGGCCACTGTCACCATCCAGCGCTGGTACCGG CACCAGGTGCAGCGGCGCGGAGCAGGAGCTGCCCGCCTGGAGCACTTGCTTCAGGCCAAG CGGGAGGAGCAGCGGCAGCGGTCAGGCGAGGGGACCCTCTTGGACCTGCACCAGCAGAAA GAGGCAGCCAGGAGGAAGGCCCGGGAGGAGAAGGCACGCCAAGCCAGGCGAGCAGCCATT CAGGAGCTGCAACAGAAACGAGCCCTGAGAGCCCAGAAGGCGAGCACTGCCGAGCGTGGG CCACCTGAGAATCCCAGGGAGACCAGAGTGCCAGGAATGCGGCAGCCTGCTCAGGAGCTG TCCCCCACACCAGGCGGCACTGCCCACCAGGCCCTCAAGGCCAACAATACTGGTGGTGGC CTCCCTGCTGCAGGCCCCGGAGACCGCTGCCTGCCCACCTCCGACTCATCCCCAGAACCA CAGCAGCCTCCAGAGGACAGGACGCAGGACGTTCTTGCCCAGGATGCAGCTGGGGACAAC CTGGAGATGATGGCCCCGAGCAGGGGGAGCGCCAAGTCCAGGGGGCCACTGGAGGAGCTG CTGCACACACTGCAGCTGCTGGAGAAGGAGCCGGACGTGCTGCCCCGCCCCAGGACCCAT CACAGGGGCAGATACGCCTGGGCCAGCGAGGAGGATGACGCCAGCTCTCTGACAGCTGAC AACTTGGAGAAATTTGGAAAACTCAGTGCGTTCCCCGAACCTCCTGAGGATGGGACGCTG CTATCGGAGGCCAAGCTACAAAGCATCATGAGCTTCTTGGACGAGATGGAGAAGTCTGGG CAGGACCAGCTGGACTCCCAGCAGGAGGGGTGGGTGCCGGAGGCGGGGCCGGGGCCCCTG GAGCTGGGGTCCGAGGTGAGCACGTCTGTGATGCGGCTGAAGCTGGAGGTGGAGGAGAAG AAGCAGGCCATGCTGCTGCTGCAGAGAGCGCTGGCGCAGCAGCGAGACCTCACGGCCCGG CGGGTCAAGGAGACAGAGAAGGCGCTGAGCCGGCAGCTGCAGCGGCAGAGGGAGCACTAC GAGGCCACCATCCAGCGGCACTTGGCCTTCATTGACCAGCTGATTGAGGACAAGAAGGTC CTGAGTGAAAAGTGCGAGGCTGTGGTGGCCGAGCTGAAGCAGGAGGACCAGAGATGCACC GAGCGTGTGGCCCAGGCACAGGCGCAGCACGAGCTGGAGATTAAAAAACTCAAAGAATTA ATGAGCGCCACCGAGAAAGCCCGCCGGGAGAAGTGGATCAGTGAGAAAACCAAGAAGATC AAGGAGGTCACTGTCCGAGGTCTGGAGCCCGAGATCCAGAAGCTGATTGCAAGGCACAAG CAGGAAGTGCGGAGGCTCAAGAGCCTGCACGAGGCGGAGCTGCTGCAGTCGGATGAGCGG GCCTCGCAGCGCTGCCTGCGCCAGGCCGAGGAGCTGCGGGAGCAGCTGGAGCGGGAGAAG GAGGCGCTGGGCCAGCAGGAGCGCGAACGTGCTCGGCAGCGGCAGCGGGCGGAGCTGGAA GAGCTGAGGCAGCAGCTGGAGGAGAGCAGCTCTGCACTGACCCGAGCCCTGAGGGCTGAG TTTGAGAAGGGCAGGGAGGAGCAGGAGCGCCGGCACCAGATGGAGCTGAATACCCTGAAG CAGCAGCTGGAGCTGGAGAGGCAGGCGTGGGAGGCCGGCCGCACCAGGAAGGAGGAGGCG TGGCTGCTGAACCGGGAACAGGAGCTGAGGGAAGAAATCCGGAAAGGCCGGGACAAGGAG ATTGAGCTGGTCATTCACCGGCTGGAGGCCGACATGGCGCTGGCCAAGGAGGAGAGTGAG AAGGCTGCCGAGAGCCGCATCAAGCGCTTACGGGACAAGTACGAGGCCGAGCTCTCCGAG CTGGAGCAGTCGGAGCGGAAGCTTCAGGAGCGGTGCTCGGAGCTGAAGGGCCAGCTTGGG GAGGCCGAGGGCGAGAATCTGCGTCTGCAGGGCCTTGTGCGGCAGAAGGAGCGGGCGCTG GAGGATGCGCAGGCGGTGAACGAGCAGCTTTCTAGCGAGCGCAGCAACCTGGCCCAGGTG ATCCGCCAGGAGTTCGAGGACCGGCTGGCAGCCTCTGAGGAGGAGACGCGGCAGGCCAAG GCCGAGCTGGCCACGCTGCAGGCCCGCCAGCAGCTGGAGCTGGAGGAGGTGCACCGGAGG GTGAAGACAGCCCTCGCGAGGAAGGAGGAGGCCGTGAGCAGCCTCCGGACACAACATGAG GCTGCGGTGAAGCGGGCCGACCACCTGGAGGAGCTGCTGGAGCAGCACAGGAGGCCCACG CCAAGTACCAAGTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_001009811 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001009811.1, NP_001009811.1 |
| RefSeq Size | 3529 bp |
| RefSeq ORF | 3522 bp |
| Locus ID | 22994 |
| UniProt ID | Q9UPN4 |
| Gene Summary | Component of centriolar satellites contributing to the building of a complex and dynamic network required to regulate cilia/flagellum formation (PubMed:17954613, PubMed:24185901). In proliferating cells, MIB1-mediated ubiquitination induces its sequestration within centriolar satellites, precluding untimely cilia formation initiation (PubMed:24121310). In contrast, during normal and ultraviolet or heat shock cellular stress-induced ciliogenesis, its non-ubiquitinated form is rapidly displaced from centriolar satellites and recruited to centrosome/basal bodies in a microtubule- and p38 MAPK-dependent manner (PubMed:24121310, PubMed:26616734). Acts also as a negative regulator of BBSome ciliary trafficking (PubMed:24550735). Plays a role in sperm flagellar formation; may be involved in the regulation of intraflagellar transport (IFT) and/or intramanchette (IMT) trafficking, which are important for axoneme extension and/or cargo delivery to the nascent sperm tail (By similarity). Required for optimal cell proliferation and cell cycle progression; may play a role in the regulation of genome stability in non-ciliogenic cells (PubMed:22797915, PubMed:26297806). Involved in centriole duplication (By similarity). Required for CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:26297806).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 3. This variant encodes isoform b, which is shorter than isoform c. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221738 | AZI1 (Myc-DDK-tagged)-Human 5-azacytidine induced 1 (AZI1), transcript variant 2 |
CNY 10,450.00 |
|
| RC221738L3 | Lenti-ORF clone of AZI1 (Myc-DDK-tagged)-Human 5-azacytidine induced 1 (AZI1), transcript variant 2 |
CNY 12,350.00 |
|
| RC221738L4 | Lenti-ORF clone of AZI1 (mGFP-tagged)-Human 5-azacytidine induced 1 (AZI1), transcript variant 2 |
CNY 12,350.00 |
|
| RG221738 | AZI1 (tGFP-tagged) - Human 5-azacytidine induced 1 (AZI1), transcript variant 2 |
CNY 11,500.00 |
