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TCF3 / E2A (TCF3) (NM_003200) Human Untagged Clone
CAT＃: SC303283
TCF3 (untagged)-Human transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3), transcript variant 1
CNY 4,880.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AGM8; bHLHb21; E2A; E47; ITF1; p75; TCF-3; VDIR |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003200 edited
GAGAATGAACCAGCCGCAGAGGATGGCGCCTGTGGGCACAGACAAGGAGCTCAGTGACCT CCTGGACTTCAGCATGATGTTCCCGCTGCCTGTCACCAACGGGAAGGGCCGGCCCGCCTC CCTGGCCGGGGCGCAGTTCGGAGGTTCAGGTCTTGAGGACCGGCCCAGCTCAGGCTCCTG GGGCAGCGGCGACCAGAGCAGCTCCTCCTTTGACCCCAGCCGGACCTTCAGCGAGGGCAC CCACTTCACTGAGTCGCACAGCAGCCTCTCTTCATCCACATTCCTGGGACCGGGACTCGG AGGCAAGAGCGGTGAGCGGGGCGCCTATGCCTCCTTCGGGAGAGACGCAGGCGTGGGCGG CCTGACTCAGGCTGGCTTCCTGTCAGGCGAGCTGGCCCTCAACAGCCCCGGGCCCCTGTC CCCTTCGGGCATGAAGGGGACCTCCCAGTACTACCCCTCCTACTCCGGCAGCTCCCGGCG GAGAGCGGCAGACGGCAGCCTAGACACGCAGCCCAAGAAGGTCCGGAAGGTCCCGCCGGG TCTTCCATCCTCGGTGTACCCACCCAGCTCAGGTGAGGACTACGGCAGGGATGCCACCGC CTACCCGTCCGCCAAGACCCCCAGCAGCACCTATCCCGCCCCCTTCTACGTGGCAGATGG CAGCCTGCACCCCTCAGCCGAGCTCTGGAGTCCCCCGGGCCAGGCGGGCTTCGGGCCCAT GCTGGGTGGGGGCTCATCCCCGCTGCCCCTCCCGCCCGGTAGCGGCCCGGTGGGCAGCAG TGGAAGCAGCAGCACGTTTGGTGGCCTGCACCAGCACGAGCGTATGGGCTACCAGCTGCA TGGAGCAGAGGTGAACGGTGGGCTCCCATCTGCATCCTCCTTCTCCTCAGCCCCCGGAGC CACGTACGGCGGCGTCTCCAGCCACACGCCGCCTGTCAGCGGGGCCGACAGCCTCCTGGG CTCCCGAGGGACCACAGCTGGCAGCTCCGGGGATGCCCTCGGCAAAGCACTGGCCTCGAT CTACTCCCCGGGTCACTCAAGCAATAACTTCTCGTCCAGCCCTTCTACCCCCGTGGGCTC CCCCCAGGGCCTGGCAGGAACGTCACAGTGGCCTCGAGCAGGAGCCCCCGGTGCCTTATC GCCCAGCTACGACGGGGGTCTCCACGGCCTGCAGAGTAAGATAGAAGACCACCTGGACGA GGCCATCCACGTGCTCCGCAGCCACGCCGTGGGCACAGCCGGCGACATGCACACGCTGCT GCCTGGCCACGGGGCGCTGGCCTCAGGTTTCACCAGTCCCATGTCGCTGGGTGGGCGGCA CGCAGGCCTGGTTGGAGGCAGCCACCCCGAGGACGGCCTCGCAGGCAGCACCAGCCTCAT GCACAACCACGCGGCCCTCCCCAGCCAGCCAGGCACCCTCCCTGACCTGTCTCGGCCTCC CGACTCCTACAGTGGGCTAGGGCGAGCAGGTGCCACGGCGGCCGCCAGCGAGATCAAGCG GGAGGAGAAGGAGGACGAGGAGAACACGTCAGCGGCTGACCACTCGGAGGAGGAGAAGAA GGAGCTGAAGGCCCCCCGGGCCCGGACCAGCCCAGACGAGGACGAGGACGACCTTCTCCC CCCAGAGCAGAAGGCCGAGCGGGAGAAGGAGCGCCGGGTGGCCAATAACGCCCGGGAGCG GCTGCGGGTCCGTGACATCAACGAGGCCTTTAAGGAGCTGGGGCGCATGTGCCAACTGCA CCTCAACAGCGAGAAGCCCCAGACCAAACTGCTCATCCTGCACCAGGCTGTCTCGGTCAT CCTGAACTTGGAGCAGCAAGTGCGAGAGCGGAACCTGAATCCCAAAGCAGCCTGTTTGAA ACGGCGAGAAGAGGAAAAGGTGTCAGGTGTGGTTGGAGACCCCCAGATGGTGCTTTCAGC TCCCCACCCAGGCCTGAGCGAAGCCCACAACCCCGCCGGGCACATGTGAAAGGTATGCCT CCGTGGGACGAGCCACCCGCTTTCAGCCCTGTGCTCTGGCCCCAGAAGCCGGACTCGAGA CCCCGGGCTTCATCCACATCCACACCTCACACACCTGTTGTCAGCATCGAGCCAACACCA ACCTGACAAGGTTCGGAGTGATGGGGGCGGCCAAGGTGACACTGGGTCCAGGAGCTCCCT GGGGCCCTGGCCTACCACTCACTGGCCTCGCTCCCCCTGTCCCCGAATCTCAGCCACCGT GTCACTCTGTGACCTGTCCCATGGATCCTGAAACTGCATCTTGGCCCTGTTGCCTGGGCT GACAGGAGCATTTTTTTTTTTTCCAGTAAACAAAACCTGAAAGCAAGCAACAAAACATAC ACTTTGTCAGAGAAGAAAAAAATGCCTTAACTATAAAAAGCGGAGAAATGGAAACATATC ACTCAAGGGGGATGCTGTGGAAACCTGGCTTATTCTTCTAAAGCCACCAGCAAATTGTGC CTAAGCGAAATATTTTTTTTAAGGAAAATAAAAACATTAGTTACAAGATTTTTTTTTTTC TTAATGTAGATGAAAATTAGCAAGGATGCTGCCTTTGGTCTCTGGTTTTTTTAAGCTTTT TTTGCATATGTTTTGTAAGCAACAAATTTTTTTGTATAAAAGTCCCGTGTCTCTCGCTAA AAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_003200 unedited
TTCAAGTCACAATTGTATACGACTCATATAGGCGGCCGCGNAATCGCCCTTGAGAATGAA CCAGCCGCAGAGGAGGCGCCTGTGGGCACAGACAAGGAGCTCAGTGACCTCCTGGACTTC AGCATGATGTTCCCGCTGCCTGTCACCAACGGGAAGGGCCGGCCCGCCTCCCTGGCCGGG GCGCAGTTCGGAGGTTCAGGTCTTGAGGACCGGCCCAGCTCAGGCTCCTGGGGCAGCGGC GACCAGAGCAGCTCCTCCTTTGACCCCAGCCGGACCTTCAGCGAGGGCACCCACTTCACT GAGTCGCACAGCAGCCTCTCTTCATCCACATTCCTGGGACCGGGACTCGGAGGCAAGAGC GGTGAGCGGGGCGCCTATGCCTCCTTCGGGAGAGACGCAGGCGTGGGCGGCCTGACTCAG GCTGGCTTCCTGTCAGGCGAGCTGGCCCTCAACAGCCCCGGGCCCCTGTCCCCTTCGGGC ATGAAGGGGACCTCCCAGTACTACCCCTCCTACTCCGGCAGCTCCCGGCGGAGAGCGGCA GACGGCAGCCTAGACACGCAGCCCAAGAAGGTCCGGAAGGTCCCGCCGGGTCTTCCATCC TCGGTGTACCCACCCAGCTCAGGTGAGGACTACGGCAGGGATGCCACCGCCTACCCGTCC GCCAAGACCCCCAGCAGCACCTATCCCGCCCCCTTCTACGTGGCAGATGGCAGCCTGCAC CCCTCAGCCGAGCTCTGGAGTCCCCCGGGCCAAGCGGGCTTCGGGCCCATGCTGGGTGGG GGCTCAATCCCGCTGGCCCTCCCGCCCGGTACGGCCCCGGGGGGCAGCAGTGGAAGCCAC A >OriGene 3' read for NM_003200 unedited
AGNAAAGCACTGGGGNAGGGTCACAGGGATGCCACCCGGGCTCTGTTCAGGAAACAGCTA TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTAGCGAGAGA CACGGGACTTTTATACAAAAAAATTTGTTGCTTACAAAACATATGCAAAAAAAGCTTAAA AAAACCAGAGACCAAAGGCAGCATCCTTGCTAATTTTCATCTACATTAAGAAAAAAAAAA ATCTTGTAACTAATGTTTTTATTTTCCTTAAAAAAAATATTTCGCTTAGGCACAATTTGC TGGTGGCTTTAGAAGAATAAGCCAGGTTTCCACAGCATCCCCCTTGAGTGATATGTTTCC ATTTCTCCGCTTTTTATAGTTAAGGCATTTTTTTCTTCTCTGACAAAGTGTATGTTTTGT TGCTTGCTTTCAGGTTTTGTTTACTGGAAAAAAAAAAAATGCTCCTGTCAGCCCAGGCAA CAGGGCCAAGATGCAGTTTCAGGATCCATGGGACAGGTCACAGAGTGACACGGTGGCTGA GATTCGGGGACAGGGGGAGCGAGGCCAGTGAGTGGTAGGCCAGGGCCCCAGGGAGCTCCT GGACCCAGTGTCACCTTGGCCGCCCCCATCACTCCGAACCTTGTCAGGTTGGTGTTGGCT CGATGCTGACAACAGGTGTGTGAGGTGTGGATGTGGATGAAGCCCGGGGTCTCGAGTGGC CGTTCTGGGGCCAGAGCCAGGGCTGAAAGCGGGTGGCTCGTCCCACGAGGCATACCTTTC AATGTGCCCGGCGGGGTTGTGGGCTTCGCTCAGCCTGGGTGGGGAGCTGAAAGCCCATCT GGGGGTCTC |
| Restriction Sites | Please inquire |
| ACCN | NM_003200 |
| Insert Size | 2700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There are 3 nucleotide differences between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substitution of 2 amino acid. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003200.1, NP_003191.1 |
| RefSeq Size | 4396 bp |
| RefSeq ORF | 1965 bp |
| Locus ID | 6929 |
| UniProt ID | P15923 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
| Gene Summary | This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (E12). This isoform is also known as Pan-2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
T Cell Factor 4 Is a Pro-catabolic and Apoptotic Factor in Human Articular Chondrocytes by Potentiating Nuclear Factor {kappa}B Signaling
,Bin Ma, Leilei Zhong, Clemens A. van Blitterswijk, Janine N. Post, and Marcel Karperien,
J. Biol. Chem., Jun 2013; 288: 17552 - 17558.
,PubMed ID 23603903
[TCF3]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215432 | TCF3 (Myc-DDK-tagged)-Human transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3), transcript variant 1 |
CNY 4,872.00 |
|
| RC215432L1 | Lenti ORF clone of Human transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3), transcript variant 1, Myc-DDK-tagged |
CNY 7,272.00 |
|
| RC215432L2 | Lenti ORF clone of Human transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3), transcript variant 1, mGFP tagged |
CNY 7,600.00 |
|
| RC215432L3 | Lenti ORF clone of Human transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3), transcript variant 1, Myc-DDK-tagged |
CNY 7,272.00 |
|
| RC215432L4 | Lenti ORF clone of Human transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3), transcript variant 1, mGFP tagged |
CNY 7,600.00 |
|
| RG215432 | TCF3 (tGFP-tagged) - Human transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3), transcript variant 1 |
CNY 6,472.00 |
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