United States
Germany
Japan
United Kingdom
China
GALR2 (NM_003857) Human Untagged Clone
CAT＃: SC303390
GALR2 (untagged)-Human galanin receptor 2 (GALR2)
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GAL2-R; GALNR2; GALR-2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003857 edited
GCTGCAGGAGCCCGGGCAGCCTCGGGGTCAGCGGCACCATGAACGTCTCGGGCTGCCCAG GGGCCGGGAACGCGAGCCAGGCGGGCGGCGGGGGAGGCTGGCACCCCGAGGCGGTCATCG TGCCCCTGCTCTTCGCGCTCATCTTCCTCGTGGGCACCGTGGGCAACACGCTGGTGCTGG CGGTGCTGCTGCGCGGCGGCCAGGCGGTCAGCACTACCAACCTGTTCATCCTTAACCTGG GCGTGGCCGACCTGTGTTTCATCCTGTGCTGCGTGCCCTTCCAGGCCACCATCTACACCC TGGACGGCTGGGTGTTCGGCTCGCTGCTGTGCAAGGCGGTGCACTTCCTCATCTTCCTCA CCATGCACGCCAGCAGCTTCACGCTGGCCGCCGTCTCCCTGGACAGGTATCTGGCCATCC GCTACCCGCTGCACTCCCGCGAGCTGCGCACGCCTCGAAACGCGCTGGCAGCCATCGGGC TCATCTGGGGGCTGTCGCTGCTCTTCTCCGGGCCCTACCTGAGCTACTACCGCCAGTCGC AGCTGGCCAACCTGACCGTGTGCCATCCCGCGTGGAGCGCCCCTCGCCGCCGCGCCATGG ACATCTGCACCTTCGTCTTCAGCTACCTGCTTCCTGTGCTGGTTCTCGGCCTGACCTACG CGCGCACCTTGCGCTACCTCTGGCGCGCCGTCGACCCGGTGGCCGCGGGCTCGGGTGCCC GGCGCGCCAAGCGCAAGGTGACACGCATGATCCTCATCGTGGCCGCGCTCTTCTGCCTCT GCTGGATGCCCCACCACGCGCTCATCCTCTGCGTGTGGTTCGGCCAGTTCCCGCTCACGC GCGCCACTTATGCGCTTCGCATCCTCTCGCACCTGGTCTCCTACGCCAACTCCTGCGTCA ACCCCATCGTTTACGCGCTGGTCTCCAAGCACTTCCGCAAAGGCTTCCGCACGATCTGCG CGGGCCTGCTGGGCCGTGCCCCAGGCCGAGCCTCGGGCCGTGTGTGCGCTGCCGCGCGGG GCACCCACAGTGGCAGCGTGTTGGAGCGCGAGTCCAGCGACCTGTTGCACATGAGCGAGG CGGCGGGGGCCCTTCGTCCCTGCCCCGGCGCTTCCCAGCCATGCATCCTCGAGCCCTGTC CTGGCCCGTCCTGGCAGGGCCCAAAGGCAGGCGACAGCATCCTGACGGTTGATGTGGCCT GAAAGCACTTAGCGGGCGCGCTGGGATGTCACAGAGTTGGAG >OriGene 5' read for NM_003857 unedited
NAACGTTCGCATTTGTATACGACTCACTATAGGCGGCCGCGATTCGCCCTTACCCANACG GCTGCAGGAGCCCGGGCAGCCTCGGGGTCAGCGGCACCATGAACGTCTCGGGCTGCCCAG GGGCCGGGAACGCGAGCCAGGCGGGCGGCGGGGGAGGCTGGCACCCCGAGGCGGTCATCG TGCCCCTGCTCTTCGCGCTCATCTTCCTCGTGGGCACCGTGGGCAACACGCTGGTGCTGG CGGTGCTGCTGCGCGGCGGCCAGGCGGTCAGCACTACCAACCTGTTCATCCTTAACCTGG GCGTGGCCGACCTGTGTTTCATCCTGTGCTGCGTGCCCTTCCAGGCCACCATCTACACCC TGGACGGCTGGGTGTTCGGCTCGCTGCTGTGCAAGGCGGTGCACTTCCTCATCTTCCTCA CCATGCACGCCAGCAGCTTCACGCTGGCCGCCGTCTCCCTGGACAGGTATCTGGCCATCC GCTACCCGCTGCACTCCCGCGAGCTGCGCACGCCTCGAAACGCGCTGGCAGCCATCGGGC TCATCTGGNGGCTGTCGCTGCTCTTCTCCGGGCCCTACCTGAGCTACTACCGCCAGTCGC AGCTGGCCAACCTGACCGTGTGCCATCCCGCGTGGAGCGCCCCTCGCCGCCGCGCCATGG ACATCTGCACCTTCGTCTTCAGCTACCTGCTTTCTGTGCTGGTTCTCGGCCTGACCTACG CGCGCACCTTGCGCTACCTCTGGCGCGCCGTCGACCCGGTGGCCGCGGGCTCGGGTTGCC CCGCGCGCCAAGCGCAAGGTGACACGCATGATCCTCATCGGGGCCGCGCTCTTCTGCCTC TGCTGGATGCCCCACAAGCGCTCATCCTTTGGGTGTGGTTCGGCCATTCCGGTTTAAGCC CGCAATT >OriGene 3' genomic read for NM_003857 unedited
ATCGGAATGGCAACTTCCAGGNCCAGNAAAGCACTGGNGGNAGGGGTCACAGGGNATGCC ACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGACAAGCTT GATATCGGTACCAGATCTGAATTCGCCCTTCTCCAACTCTGTGACATCCCAGCGCGCCCG CTAAGTGCTTTCAGGCCACATCAACCGTCAGGATGCTGTCGCCTGCCTTTGGGCCCTGCC AGGACGGGCCAGGACAGGGCTCGAGGATGCATGGCTGGGAAGCGCCGGGGCAGGGACGAA GGGCCCCCGCCGCCTCGCTCATGTGCAACAGGTCGCTGGACTCGCGCTCCAACACGCTGC CACTGTGGGTGCCCCGCGCGGCAGCGCACACACGGCCCGAGGCTCGGCCTGGGGCACGGC CCAGCAGGCCCGCGCAGATCGTGCGGAAGCCTTTGCGGAAGTGCTTGGAGACCAGCGCGT AAACGATGGGGTTGACGCAGGAGTTGGCGTANGAGACCAGGTGCGAGAGGATGCGAAGCG CATAAGTGGCGCGCGTGAGCGGGAACTGGCCGAACCACACGCAGAGGATGAGCGCGTGGT GNGGCATCCAGCAGAGGCAGAAGAGCGCGGCCACGATGAGGATCATGCGTGTCACCTTGC GCTTGGCGCGCCCGGGCACCCGAGCCCGCGGCCACCCGGGTCGACGGCGCGNCAGAAGTA GCGCAAGGTGCGCGCGGTAGTCANGCCGAGAACCAGCACAGGAAGCAGGTAGCTGAAGAC GAAAGTGCAAATGTCCATGGCCCGGCGGCCAGGGGCGCTCCACGCGGGGAAGGCCCAN |
| Restriction Sites | Please inquire |
| ACCN | NM_003857 |
| Insert Size | 1200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003857.2, NP_003848.1 |
| RefSeq Size | 1309 bp |
| RefSeq ORF | 1164 bp |
| Locus ID | 8811 |
| UniProt ID | O43603 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222436 | GALR2 (Myc-DDK-tagged)-Human galanin receptor 2 (GALR2) |
CNY 3,656.00 |
|
| RC222436L1 | Lenti ORF clone of Human galanin receptor 2 (GALR2), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC222436L2 | Lenti ORF clone of Human galanin receptor 2 (GALR2), mGFP tagged |
CNY 5,890.00 |
|
| RC222436L3 | Lenti ORF clone of Human galanin receptor 2 (GALR2), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC222436L4 | Lenti ORF clone of Human galanin receptor 2 (GALR2), mGFP tagged |
CNY 5,890.00 |
|
| RG222436 | GALR2 (tGFP-tagged) - Human galanin receptor 2 (GALR2) |
CNY 5,256.00 |
