United States
Germany
Japan
United Kingdom
China
EMX2 (NM_004098) Human Untagged Clone
CAT＃: SC303433
EMX2 (untagged)-Human empty spiracles homeobox 2 (EMX2), transcript variant 1
CNY 3,600.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004098 edited
TCCCCAATTCTCGTCCGTCCTCGCCGCGGGCAGCGGGCGGCGGAGGCAGCGTGCGGCGGT CGCCAGGAGCTGGGAGCCCAGGGCGCCCGCTCCTCGGCGCAGCATGTTCCAGCCGGCGCC CAAGCGCTGCTTCACCATCGAGTCGCTGGTGGCCAAGGACAGTCCCCTGCCCGCCTCGCG CTCCGAGGACCCCATCCGTCCCGCGGCACTCAGCTACGCTAACTCCAGCCCCATAAATCC GTTCCTCAACGGCTTCCACTCGGCCGCCGCCGCCGCCGCCGGTAGGGGCGTCTACTCCAA CCCGGACTTGGTGTTCGCCGAGGCGGTCTCGCACCCGCCCAACCCCGCCGTGCCAGTGCA CCCGGTGCCGCCGCCGCACGCCCTGGCCGCCCACCCCCTACCCTCCTCGCACTCGCCACA CCCCCTATTCGCCTCGCAGCAGCGGGATCCGTCCACCTTCTACCCCTGGCTCATCCACCG CTACCGATATCTGGGTCATCGCTTCCAAGGGAACGACACTAGCCCCGAGAGTTTCCTTTT GCACAACGCGCTGGCCCGAAAGCCCAAGCGGATCCGAACCGCCTTCTCCCCGTCCCAGCT TCTAAGGCTGGAACACGCCTTTGAGAAGAATCACTACGTGGTGGGCGCCGAAAGGAAGCA GCTGGCACACAGCCTCAGCCTCACGGAAACTCAGGTAAAAGTATGGTTTCAGAACCGAAG AACAAAGTTCAAAAGGCAGAAGCTGGAGGAAGAAGGCTCAGATTCGCAACAAAAGAAAAA AGGGACGCACCATATTAACCGGTGGAGAATCGCCACCAAGCAGGCGAGTCCGGAGGAAAT AGACGTGACCTCAGATGATTAAAAACATAAACCTAACCCCACAGAAACGGACAACATGGA GCAA >OriGene 5' read for NM_004098 unedited
GTCAGCATTTGTATACGACTCATATAGGGCGGCCGCGATTCANATCTGGTACCGAGCTCG GATCCACTAGTAACGGCCGCCATGTGCTGGAATTCGCCCTTCCCCAATTCTCGTCCGTCC TCGCCGCGGGCAGCGGGCGGCGGAGGCAGCGTGCGGCGGTCGCCAGGAGCTGGGAGCCCA GGGCGCCCGCTCCTCGGCGCAGCATGTTCCAGCCGGCGCCCAAGCGCTGCTTCACCATCG AGTCGCTGGTGGCCAAGGACAGTCCCCTGCCCGCCTCGCGCTCCGAGGACCCCATCCGTC CCGCGGCACTCAGCTACGCTAACTCCAGCCCCATAAATCCGTTCCTCAACGGCTTCCACT CGGCCGCCGCCGCCGCCGCCGGTAGGGGCGTCTACTCCAACCCGGACTTGGTGTTCGCCG AGGCGGTCTCGCACCCGCCCAACCCCGCCGTGCCAGTGCACCCGGTGCCGCCGCCGCACG CCCTGGCCGCCCACCCCCTACCCTCCTCGCACTCGCCACACCCCCTATTCGCCTCGCAGC AGCGGGATCCGTCCACCTTCTACCCCTGGCTCATCCACCGCTACCGATATCTGGGTCATC GCTTCCAAGGGAACGACACTAGCCCCGAGAGTTTCCTTTTGCACAACGCGCTGGCCCGAA AGCCCAAGCGGATCCGAACCGCCTTCTCCCCGTCCCAGCTTCTAAGGCTGGAACACGCCT TTGAGAAGAATCACTACGTGGTGGGCGCCGAAAGGAAGCAGCTGGCACACAGCCTCAGCC TCACGGGAACTCANGTAAAAGTATGA |
| Restriction Sites | Please inquire |
| ACCN | NM_004098 |
| Insert Size | 900 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004098.2, NP_004089.1 |
| RefSeq Size | 2907 bp |
| RefSeq ORF | 759 bp |
| Locus ID | 2018 |
| UniProt ID | Q04743 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.[provided by RefSeq, Sep 2009] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The expression of EMX2 lead to cell cycle arrest in glioblastoma cell line
,Monnier, A;Boniface, R;Bouvet, R;Etcheverry, A;Aubry, M;Avril, T;Quillien, V;Chevet, E;Mosser, J;,
BMC Cancer
,PubMed ID 30514244
[EMX2]
|
|
EMX2 Is a Predictive Marker for Adjuvant Chemotherapy in Lung Squamous Cell Carcinomas
,Yue, D;Li, H;Che, J;Zhang, Y;Tolani, B;Mo, M;Zhang, H;Zheng, Q;Yang, Y;Cheng, R;Jin, JQ;Luh, TW;Yang, C;Tseng, HH;Giroux-Leprieur, E;Woodard, GA;Hao, X;Wang, C;Jablons, DM;He, B;,
PLoS ONE
,PubMed ID 26132438
[EMX2]
|
|
EMX2 is epigenetically silenced and suppresses growth in human lung cancer
,J Okamoto, T Hirata, Z Chen, H-M Zhou, I Mikami, H Li, A Beltran, M Johansson, L M Coussens, G Clement, et al.,
Oncogene (9 August 2010) doi:10.1038/onc.2010.330 Short Communication
[EMX2]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222758 | EMX2 (Myc-DDK-tagged)-Human empty spiracles homeobox 2 (EMX2), transcript variant 1 |
CNY 3,600.00 |
|
| RC222758L1 | Lenti ORF clone of Human empty spiracles homeobox 2 (EMX2), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC222758L2 | Lenti ORF clone of Human empty spiracles homeobox 2 (EMX2), transcript variant 1, mGFP tagged |
CNY 6,000.00 |
|
| RC222758L3 | Lenti ORF clone of Human empty spiracles homeobox 2 (EMX2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC222758L4 | Lenti ORF clone of Human empty spiracles homeobox 2 (EMX2), transcript variant 1, mGFP tagged |
CNY 6,000.00 |
|
| RG222758 | EMX2 (tGFP-tagged) - Human empty spiracles homeobox 2 (EMX2), transcript variant 1 |
CNY 5,200.00 |
