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CHD3 (NM_005852) Human Untagged Clone
CAT＃: SC303698
CHD3 (untagged)-Human chromodomain helicase DNA binding protein 3 (CHD3), transcript variant 2
CNY 37,910.00
货期*
8周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Mi-2a; Mi2-ALPHA; SNIBCPS; ZFH |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_005852, the custom clone sequence may differ by one or more nucleotides
ATGAAGGCGGCAGACACTGTGATCCTGTGGGCAAGAAGTAAAAATGACCAGCTGAGGATT TCTTTTCCTCCAGGACTGTGTTGGGGTGACAGGATGCCTGATAAGGATGACATTCGGCTG CTGCCGTCAGCATTGGGTGTGAAGAAGAGAAAACGAGGACCCAAGAAGCAGAAGGAGAAC AAGCCAGGAAAACCCCGAAAACGCAAGAAGCGTGACAGTGAGGAGGAATTTGGTTCTGAG CGAGATGAGTACCGGGAGAAGTCAGAGAGTGGGGGCAGTGAATATGGAACCGGACCGGGT CGGAAACGAAGAAGGAAGCACCGAGAAAAAAAGGAGAAGAAGACAAAGCGGCGGAAAAAG GGGGAGGGAGATGGGGGGCAAAAGCAAGTGGAACAGAAGTCATCAGCAACTCTGCTTCTG ACCTGGGGCCTGGAGGATGTGGAGCATGTGTTCTCTGAGGAGGATTACCACACGCTCACC AACTACAAAGCCTTCAGCCAGTTCATGAGGCCCCTAATTGCTAAGAAGAATCCTAAGATC CCAATGTCTAAGATGATGACCATCCTTGGGGCCAAATGGAGAGAGTTCAGTGCCAACAAC CCCTTCAAGGGGTCAGCAGCTGCTGTGGCGGCGGCAGCGGCAGCAGCAGCAGCAGCTGTA GCTGAGCAGGTGTCAGCTGCTGTCTCGTCGGCCACCCCCATAGCACCCTCCGGACCCCCC GCCCTTCCACCACCCCCTGCTGCTGATATCCAGCCCCCACCCATCCGAAGAGCCAAAACC AAAGAGGGCAAAGGTCCAGGCCATAAGAGGCGGAGTAAGAGCCCCCGAGTGCCTGATGGA CGCAAGAAGCTTCGGGGAAAGAAAATGGCACCACTCAAAATAAAACTAGGGCTTCTGGGT GGCAAGAGGAAGAAAGGAGGCTCGTATGTTTTTCAGAGCGACGAAGGTCCTGAACCAGAG GCTGAGGAATCAGACCTGGACAGTGGCAGTGTCCACAGTGCCTCAGGCCGGCCTGATGGC CCTGTCCGCACCAAGAAACTAAAGAGAGGCCGGCCAGGAAGGAAGAAGAAGAAGGTCCTG GGCTGTCCTGCAGTGGCCGGGGAGGAGGAGGTTGATGGCTACGAGACGGATCACCAGGAT TACTGTGAGGTGTGCCAGCAGGGTGGGGAAATTATTCTGTGTGACACCTGCCCTCGTGCC TACCACCTCGTCTGCCTTGATCCTGAGCTTGACCGGGCTCCAGAGGGCAAATGGAGCTGC CCTCACTGTGAGAAGGAGGGGGTCCAGTGGGAGGCCAAGGAGGAAGAAGAAGAATACGAA GAGGAGGGAGAGGAAGAAGGGGAGAAGGAGGAGGAGGATGATCACATGGAGTACTGCCGC GTATGCAAGGACGGCGGGGAGCTCCTGTGCTGTGACGCGTGCATCTCCTCCTACCACATT CATTGTCTAAACCCTCCCCTGCCTGACATTCCCAATGGTGAATGGCTGTGTCCCCGATGC ACATGCCCCGTGCTGAAGGGTCGAGTGCAGAAGATCCTACATTGGCGGTGGGGGGAGCCA CCTGTAGCAGTGCCAGCCCCTCAACAGGCAGATGGAAATCCAGATGTCCCACCCCCCCGT CCTCTTCAAGGCAGATCAGAGCGAGAGTTCTTTGTCAAGTGGGTAGGACTATCCTACTGG CACTGCTCCTGGGCCAAGGAGCTTCAGCTGGAAATCTTCCATTTGGTTATGTATCGAAAC TACCAGCGGAAGAATGACATGGATGAGCCCCCACCCCTGGACTATGGCTCCGGCGAGGAT GATGGGAAGAGCGACAAGCGTAAAGTGAAAGACCCGCACTATGCTGAGATGGAGGAGAAG TACTATCGTTTTGGCATCAAGCCAGAGTGGATGACCGTCCACCGCATCATCAACCACAGT GTGGATAAAAAGGGGAATTACCACTATCTAGTAAAATGGAGGGACTTACCATATGACCAG TCCACGTGGGAGGAAGATGAAATGAATATCCCTGAATACGAAGAACATAAGCAAAGCTAC TGGAGACACCGAGAACTAATTATGGGGGAAGACCCTGCCCAGCCCCGCAAGTATAAGAAG AAGAAGAAGGAGCTACAGGGTGATGGGCCTCCCAGTTCTCCCACTAATGATCCTACCGTG AAATATGAGACTCAGCCACGGTTTATCACAGCCACTGGAGGCACCCTGCACATGTATCAG TTGGAAGGGCTGAACTGGCTACGCTTCTCCTGGGCCCAGGGCACTGACACCATTCTAGCT GATGAGATGGGGCTAGGCAAGACCATACAAACCATCGTCTTCCTCTACTCACTCTACAAG GAGGGCCACACAAAAGGTCCCTTCCTGGTGAGTGCCCCACTCTCTACCATCATTAACTGG GAGCGGGAGTTCCAGATGTGGGCACCCAAATTCTATGTGGTGACATACACGGGTGACAAG GACAGCCGGGCCATCATTCGTGAGAATGAATTCTCCTTTGAGGACAATGCCATCAAAGGG GGCAAGAAAGCTTTTAAGATGAAGAGGGAGGCACAGGTGAAGTTCCATGTTCTCCTGACA TCGTATGAGCTGATCACCATTGATCAGGCAGCACTTGGTTCCATCCGCTGGGCCTGTCTT GTGGTAGATGAGGCCCATCGACTCAAGAACAACCAGTCCAAGTTTTTCAGGGTTCTCAAT GGTTACAAGATAGATCATAAGTTGCTGCTGACAGGAACCCCATTGCAGAATAATCTGGAG GAGCTCTTCCATCTCCTGAACTTCCTCACCCCAGAGAGATTTAACAACTTGGAGGGCTTC CTGGAGGAGTTTGCTGACATATCCAAAGAGGACCAGATCAAGAAACTGCATGATTTGCTG GGGCCACACATGCTGCGGAGACTCAAGGCAGATGTCTTTAAGAACATGCCAGCCAAGACA GAGCTCATCGTTCGGGTGGAGCTAAGCCCCATGCAGAAGAAATACTACAAATACATCCTG ACTCGAAATTTTGAGGCCTTGAATTCACGAGGTGGTGGGAACCAGGTGTCGCTGCTTAAT ATCATGATGGATCTTAAGAAGTGCTGCAACCATCCATACCTTTTTCCCGTGGCTGCTATG GAGTCCCCCAAACTCCCCAGTGGGGCTTATGAGGGTGGGGCACTTATTAAGTCGTCTGGG AAGCTCATGCTGCTCCAGAAGATGCTGCGAAAGCTGAAGGAGCAAGGACACCGAGTGCTC ATCTTCTCGCAGATGACCAAAATGTTAGACTTGCTTGAGGACTTCTTAGACTATGAAGGC TACAAGTATGAGCGCATCGATGGTGGTATCACGGGTGCCCTGAGGCAGGAGGCCATCGAT CGGTTTAATGCTCCTGGGGCCCAACAATTCTGCTTCCTCCTGTCCACCCGAGCTGGGGGC CTGGGCATCAATCTGGCCACTGCTGACACTGTCATCATCTTTGATTCTGACTGGAACCCC CATAATGACATCCAGGCCTTTAGCCGGGCTCATCGGATTGGCCAGGCCAACAAAGTGATG ATTTACCGGTTTGTGACTCGCGCGTCAGTGGAAGAGCGAATCACACAAGTGGCCAAGAGA AAGATGATGCTGACACACCTGGTTGTGCGGCCTGGGCTGGGCTCCAAGGCAGGCTCCATG TCCAAGCAGGAGCTTGACGACATTCTCAAATTTGGCACTGAAGAGCTATTCAAGGATGAA AACGAGGGGGAGAACAAGGAGGAGGACAGCAGTGTGATTCATTATGACAATGAGGCCATC GCTCGGCTGTTGGACCGGAACCAGGATGCAACTGAGGACACTGACGTGCAGAACATGAAT GAGTATCTCAGCTCCTTCAAGGTGGCACAGTACGTCGTGCGGGAAGAAGACAAGATTGAG GAAATTGAGCGAGAGATCATCAAGCAGGAGGAGAATGTGGACCCTGACTACTGGGAGAAG CTGCTGAGGCATCACTATGAGCAACAGCAGGAAGACCTAGCCCGGAATCTAGGCAAGGGC AAGCGGGTTCGCAAGCAAGTTAACTACAATGATGCTGCTCAGGAAGACCAAGACAACCAG TCAGAGTACTCGGTGGGTTCAGAGGAGGAGGATGAAGACTTCGATGAACGTCCTGAAGGG CGTAGACAGTCAAAGAGGCAGCTCCGGAATGAGAAAGATAAGCCACTGCCTCCACTGCTG GCCCGAGTCGGGGGCAACATTGAGGTGCTGGGCTTCAACACCCGTCAGCGGAAGGCTTTC CTCAATGCTGTGATGCGCTGGGGGATGCCACCACAGGATGCCTTCACCACACAGTGGCTG GTGCGGGACCTGAGGGGCAAGACTGAGAAGGAGTTTAAGGCCTATGTGTCTTTGTTCATG CGCCATCTGTGTGAGCCTGGGGCAGACGGCTCTGAAACCTTTGCCGATGGGGTCCCTCGG GAGGGACTGAGTCGCCAGCAGGTGTTGACCCGCATTGGAGTCATGTCTCTCGTCAAAAAG AAGGTGCAGGAGTTTGAGCACATCAATGGGCGTTGGTCAATGCCGGAACTGATGCCTGAC CCCAGCGCCGATTCTAAGCGCTCCTCCAGAGCCTCCTCTCCTACCAAAACGTCTCCCACC ACTCCTGAGGCTTCTGCTACCAACAGTCCCTGCACCTCTAAACCTGCTACTCCAGCTCCA AGTGAGAAAGGAGAAGGCATAAGGACACCTCTTGAGAAGGAGGAAGCTGAAAACCAGGAG GAAAAGCCAGAGAAGAACAGCAGAATTGGGGAGAAGATGGAGACAGAGGCTGATGCCCCC AGCCCAGCCCCATCACTTGGGGAGCGGCTGGAGCCAAGGAAGATTCCTCTAGAGGATGAG GTGCCAGGGGTGCCTGGAGAGATGGAGCCTGAACCTGGGTACCGTGGGGACAGAGAGAAG TCAGAAGATGTAAAAGGTGACCGGGAGCTTCGACCAGGGCCTCGAGATGAGCCACGGTCC AATGGGCGACGAGAGGAAAAGACAGAGAAGCCCCGGTTCATGTTCAATATCGCCGATGGT GGCTTCACAGAGCTTCACACACTGTGGCAGAATGAGGAACGGGCAGCTATTTCCTCGGGG AAACTCAATGAGATCTGGCACAGAAGACATGACTATTGGCTTCTGGCTGGGATTGTCCTC CATGGCTATGCACGGTGGCAGGACATCCAGAATGATGCTCAATTTGCCATTATCAACGAG CCATTTAAAACTGAAGCCAATAAGGGGAACTTTCTGGAGATGAAAAATAAGTTCCTGGCC CGGAGGTTCAAGCTCCTGGAGCAGGCGCTGGTGATTGAGGAGCAGCTGCGGCGGGCGGCC TACCTGAACCTGTCGCAGGAGCCGGCGCACCCCGCCATGGCCCTCCACGCCCGCTTCGCC GAGGCCGAGTGCCTGGCCGAGAGCCACCAGCACCTCTCCAAGGAGTCGCTGGCGGGGAAC AAGCCGGCCAACGCCGTCCTGCACAAGGTTCTGAACCAGCTGGAGGAGTTGCTGAGCGAC ATGAAGGCGGACGTGACCCGCCTGCCAGCCACGCTGTCCCGAATACCCCCCATCGCAGCC CGCCTTCAGATGTCCGAGCGCAGCATCCTCAGCCGGCTGGCCAGCAAGGGCACGGAGCCT CACCCCACACCGGCCTACCCGCCGGGTCCCTACGCTACACCTCCGGGGTACGGGGCGGCC TTCAGCGCCGCACCCGTAGGGGCCCTGGCCGCCGCAGGCGCCAATTACAGCCAGATGCCT GCAGGGTCCTTCATCACAGCCGCCACCAACGGCCCTCCAGTGCTTGTGAAGAAGGAGAAG GAAATGGTGGGGGCATTGGTGTCAGACGGGCTGGATCGGAAGGAGCCCCGAGCCGGGGAG GTGATCTGTATAGACGACTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_005852 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005852.2, NP_005843.2 |
| RefSeq Size | 6729 bp |
| RefSeq ORF | 5901 bp |
| Locus ID | 1107 |
| UniProt ID | Q12873 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' CDS, compared to variant 1. The resulting protein (isoform 2) is shorter, compared to isoform 1. |
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