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PRODH2 (NM_021232) Human Untagged Clone
CAT＃: SC304927
PRODH2 (untagged)-Human proline dehydrogenase (oxidase) 2 (PRODH2)
CNY 8,650.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HSPOX1; HYPDH |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_021232 edited
TAGAGATGGGGTCTCACTATGTCGCCCAGGGTAGTCTCAAACTCCTCGGTCTTGGCCTCC CAAAGTGTTGGGATTACAAACGTGAGAACCGTATTTTCAAATGTATTCAATAACACTACA GCGTTTCCAATTTTAAGAGGAAGCAATTGCCACAAAATCACTGCCCCTGGTCTGGGCAAG GGGCAGTTGGTGAACTTGCTGCCTCCAGAGAACCTTCCCTGGTGTGGAGGCAGCCAGGGA CCCAGGATGCTCCGGACCTGTTACGTGCTCTGTTCCCAAGCTGGTCCCCCCTCCAGGGGC TGGCAGTCCCTGAGCTTTGATGGCGGGGCCTTCCACCTTAAGGGCACAGGAGAGCTGACA CGGGCCTTGCTGGTTCTCCGGCTGTGTGCCTGGCCCCCACTCGTCACTCACGGGCTGTTG CTCCAGGCCTGGTCTCGGCGACTCCTGGGCTCCCGGCTCTCAGGCGCATTTCTCCGAGCA TCCGTCTATGGGCAGTTTGTGGCTGGTGAGACAGCAGAGGAGGTGAAGGGCTGCGTGCAG CAGCTGCGGACCCTCAGCCTCCGACCACTGCTGGCAGTGCCCACTGAGGAGGAGCCGGAC TCTGCTGCCAAGAGTGGTGAGGCGTGGTATGAGGGGAACCTCGGTGCTATGCTGCGGTGT GTGGACCTGTCACGGGGCCTCCTGGAGCCCCCCAGCCTGGCTGAGGCCAGCCTCATGCAG CTGAAGGTGACGGCGCTGACCAGTACTCGGCTCTGTAAGGAGCTAGCCTCGTGGGTCAGA AGGCCGGGAGCCTCCTTGGAGCTGAGCCCCGAGAGGCTGGCTGAAGCTATGGACTCTGGG CAGAACCTCCAGGTCTCCTGCCTCAATGCTGAGCAGAACCAGCACCTCCGGGCCTCCCTC AGCCGCCTGCATCGGGTGGCACAGTATGCCCGGGCCCAGCACGTGCGGCTCCTGGTGGAT GCGGAGTACACCTCACTGAACCCTGCGCTCTCGCTGCTGGTGGCTGCCCTGGCTGTGCGC TGGAACAGCCCGGGTGAAGGCGGGCCCTGGGTGTGGAACACCTACCAGGCCTGTCTAAAG GACACATTCGAGCGGCTGGGGAGGGATGCAGAGGCTGCGCACAGGGCCGGCCTGGCCTTC GGAGTGAAGCTGGTACGAGGTGCATATCTGGACAAGGAGAGAGCGGTGGCCCAGCTCCAT GGGATGGAAGACCCCACTCAGCCTGACTATGAGGCCACCAGTCAGAGTTACAGCCGCTGC CTGGAACTGATGCTGACGCACGTGGCCCGCCATGGCCCCATGTGCCACCTCATGGTGGCT TCCCACAATGAGGAATCTGTTCGCCAGGCAACCAAGCGCATGTGGGAGCTGGGCATTCCT CTGGATGGGACTGTCTGTTTCGGACAACTTCTGGGCATGTGTGACCACGTCTCTCTAGCA CTGGGGCAGGCCGGCTATGTAGTGTATAAGTCCATTCCCTATGGCTCCTTGGAGGAGGTA ATCCCCTACCTGATCCGGAGGGCCCAGGAGAACCGGAGCGTGCTTCAGGGTGCCCGCAGG GAACAGGAGCTGCTCAGCCAAGAACTGTGGCGGCGGCTGCTGCCAGGATGCCGAAGGATA CCCCACTAGCACCCCTGAGGGGGTCATGTGGTCAATAAA >OriGene 5' read for NM_021232 unedited
AGTTAAATTTGTATACCATCATATAGGCGGCCGCGNATTCGCCCTTCTCACTATGTCGCC CAGGTAGTCTCAAACTCCTCGGTCTTGGCCTCCCAAATGTTGGGATTACAAACGTGAGAA CCGTATTTTCAAATGTATTCAATAACACTACAGCGTTTCCAATTTTAAGAGGAAGCAATT GCCACAAAATCACTGCCCCTGGTCTGGGCAAGGGGCAGTTGGTGAACTTGCTGCCTCCAG AGAACCTTCCCTGGTGTGGAGGCAGCCAGGGACCCAGGATGCTCCGGACCTGTTACGTGC TCTGTTCCCAAGCTGGTCCCCCCTCCAGGGGCTGGCAGTCCCTGAGCTTTGATGGCGGGG CCTTCCACCTTAAGGGCACAGGAGAGCTGACACGGGCCTTGCTGGTTCTCCGGCTGTGTG CCTGGCCCCCACTCGTCACTCACGGGCTGTTGCTCCAGGCCTGGTCTCGGCGACTCCTGN GCTCCCGGCTCTCAGGCGCATTTCTCCGAGCATCCGTCTATGGGCAGTTTGTGGCTGGTG AGACAGCAGAGGAGGTGAAGGGCTGCGTGCAGCAGCTGCGGACCCTCAGCCTCCGACCAC TGCTGGCAGTGCCCACTGAGGAGGAGCCGGACTCTGCTGCCAAGAGTGGTGAGGCGTGGT ATGAGGGGAACCTCGGTGCTATGCTGCGGTGTGTGGACCTGTCACGGGGCCTCCTGGAGC CCCCCAGCCTGGCTGANGCCAGCCTCATGCAGCTGAAGGTGACGGCGCTGACCAGTACTC GGCTCTGTAAGGAGCTAGCCTCGTGGGTCAGAAGGCCGGGAGCC >OriGene 3' read for NM_021232 unedited
CCCACCTAGGNNGATGGCACTTNCCAGGNCCAGNAAAGCACTGGGGNAGGGTCACAGGNT GCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGACAAG CTTGATATCGGTACCAGATCTGAATTCGCCCTTTATTGACCACATGACCCCCTCAGGGGT GCTAGTGGGGTATCCTTCGGCATCCTGGCAGCAGCCGCCGCCACAGTTCTTGGCTGAGCA GCTCCTGTTCCCTGCGGGCACCCTGAAGCACGCTCCGGTTCTCCTGGGCCCTCCGGATCA GGTAGGGGATTACCTCCTCCAAGGAGCCATAGGGAATGGACTTATACACTACATAGCCGG CCTGCCCCAGTGCTAGAGAGACGTGGTCACACATGCCCAGAAGTTGTCCGAAACAGACAG TCCCATCCAGAGGAATGCCCAGCTCCCACATGCGCTTGGTTGCCTGGCGAACAGATTCCT CATTGTGGGAAGCCACCATGAGGTGGCACATGGGGCCATGGCGGGCCACGTGCGTCAGCA TCAGTTCCAGGCAGCGGCTGTAACTCTGACTGGTGGCCTCATAGTCAGGCTGAGTGGGGT CTTCCATCCCATGGAGCTGGGCCACCGCTCTCTCCTTGTCCAGATATGCACCTCGTACCA GCTTCACTCCGAAGGCCAGGCCGGCCCTGTGCGCAGCCTCTGCATCCCTCCCCAGCCGCT CGAATGTGTCCTTTAGACAGGCCTGGTAGGTGTTCCACACCCAGGGCCCGCCTTCACCCG GGCTGTTCCAGCGCACAGCCAGGGCAGCCACCAGCAGCGAGAGCGCAGGT |
| Restriction Sites | Please inquire |
| ACCN | NM_021232 |
| Insert Size | 1700 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021232.1, NP_067055.1 |
| RefSeq Size | 1677 bp |
| RefSeq ORF | 1611 bp |
| Locus ID | 58510 |
| UniProt ID | Q9UF12 |
| Protein Pathways | Arginine and proline metabolism, Metabolic pathways |
| Gene Summary | The protein encoded by this gene catalyzes the first step in the catabolism of trans-4-hydroxy-L-proline, an amino acid derivative obtained through food intake and collagen turnover. One of the downstream products of this catabolism is glyoxylate, which in people with disorders of glyoxalate metabolism can lead to an increase in oxalate levels and the formation of calcium-oxalate kidney stones. Therefore, this gene may serve as a therapeutic target against primary hyperoxalurias (PH). This gene is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme that catalyzes the first step in proline catabolism. [provided by RefSeq, Jan 2017] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215144 | PRODH2 (Myc-DDK-tagged)-Human proline dehydrogenase (oxidase) 2 (PRODH2) |
CNY 5,984.00 |
|
| RC215144L1 | Lenti ORF clone of Human proline dehydrogenase (oxidase) 2 (PRODH2), Myc-DDK-tagged |
CNY 8,384.00 |
|
| RC215144L2 | Lenti ORF clone of Human proline dehydrogenase (oxidase) 2 (PRODH2), mGFP tagged |
CNY 8,384.00 |
|
| RC215144L3 | Lenti ORF clone of Human proline dehydrogenase (oxidase) 2 (PRODH2), Myc-DDK-tagged |
CNY 6,650.00 |
|
| RC215144L4 | Lenti ORF clone of Human proline dehydrogenase (oxidase) 2 (PRODH2), mGFP tagged |
CNY 6,650.00 |
|
| RG215144 | PRODH2 (tGFP-tagged) - Human proline dehydrogenase (oxidase) 2 (PRODH2) |
CNY 7,584.00 |
