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TBX1 (NM_080647) Human Untagged Clone
CAT＃: SC305810
TBX1 (untagged)-Human T-box 1 (TBX1), transcript variant C
CNY 7,890.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAFS; CATCH22; CTHM; DGCR; DGS; DORV; TBX1C; TGA; VCF; VCFS |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_080647 edited
ATGCACTTCAGCACCGTCACCAGGGACATGGAAGCCTTCACGGCCAGCAGCCTGAGCAGC CTGGGGGCCGCGGGGGGCTTCCCGGGCGCCGCGTCGCCCGGCGCCGACCCGTACGGCCCG CGCGAGCCCCCGCCGCCGCCGCGCTACGACCCGTGCGCCGCCGCCGCCCCCGGCGCCCCG GGTCCGCCGCCGCCGCCGCACGCCTACCCGTTTGCGCCGGCCGCCGGGGCCGCCACCAGC GCCGCCGCCGAGCCCGAGGGCCCCGGGGCCAGCTGCGCGGCCGCAGCCAAGGCGCCGGTG AAGAAGAACGCGAAGGTGGCCGGTGTGAGCGTGCAGCTAGAGATGAAGGCGCTGTGGGAC GAGTTCAACCAGCTGGGCACCGAGATGATCGTCACCAAGGCCGGCAGGCGGATGTTTCCC ACCTTCCAAGTGAAGCTCTTCGGCATGGATCCCATGGCCGACTATATGCTGCTCATGGAC TTCGTGCCGGTGGACGATAAGCGCTACCGGTACGCCTTCCACAGCTCCTCCTGGCTGGTG GCGGGGAAGGCCGACCCTGCCACGCCAGGCCGCGTGCACTACCACCCGGACTCGCCTGCC AAGGGCGCGCAGTGGATGAAGCAAATCGTGTCCTTCGACAAGCTCAAGCTGACCAACAAC TTACTGGACGACAACGGCCACATTATTCTGAATTCCATGCACAGATACCAGCCCCGCTTC CACGTGGTCTATGTGGACCCACGCAAAGATAGCGAGAAATATGCCGAGGAGAACTTCAAA ACCTTTGTGTTCGAGGAGACACGATTCACCGCGGTCACTGCCTACCAGAACCATCGGATC ACGCAGCTCAAGATTGCCAGCAATCCCTTCGCGAAAGGCTTCCGGGACTGTGACCCTGAG GACTGGCCCCGGAACCACCGGCCCGGCGCACTGCCGCTCATGAGCGCCTTCGCGCGCTCG CGGAACCCCGTGGCTTCCCCGACGCAGCCCAGCGGCACGGAGAAAGACGCGGCTGAGGCC CGGCGAGAATTCCAGCGCGACGCGGGCGGGCCAGCGGTGCTCGGGGACCCGGCGCATCCT CCGCAGCTGCTGGCCCGGGTGCTAAGCCCCTCGCTGCCCGGGGCCGGCGGCGCCGGCGGC TTAGTCCCGCTGCCCGGCGCGCCCGGAGGCCGGCCCAGTCCCCCGAACCCCGAGCTGCGC CTGGAGGCGCCCGGCGCATCGGAGCCGCTGCACCACCACCCCTACAAATATCCGGCCGCC GCCTACGACCACTATCTCGGGGCCAAGAGCCGGCCGGCGCCCTACCCGCTGCCCGGCCTG CGTGGCCACGGCTACCACCCGCACGGGCATCCGCACCACCACCACCACCCCGTGAGTCCA GCCGCCGCGGCCGCCGCCGCCGCTGCCGCAGCTGCCGCGGCCGCCAACATGTACTCGTCG GCCGGAGCCGCGCCGCCCGGCTCCTACGACTATTGCCCCAGATAACACGGGCCCTGTCGC GCTCCCGCCCCGGTCCTGCACAGCCCCGAAGTTCGCCGGGCCCGGCCACCCTGCCCCAAG GGCAAGCAAGGAATACGTTCCCCCAGCCCCAGGGGCCACCGCGGCTCTCCCCTTCCCCAG CCTCGAAGCCATGGGGGCCCCCTCGCCACCCCCAGCCCCTTGGGCTATCGAAGTATCCGG TTCCCCAGTCCCTGGAGCCACCGCGGGTCCTTCCCCGGCCCCGAGGGCCAAGGGGGTCCC CGCCCGCCAGTGCCAAAGCGCCCGGTCGGAGGCGGAAGGAAGTGATATTTATTGTTCTCC CCGAGACCGCGTCGCCCGCGGCCCGGCCGGCAGTTGCAGTGTAGACAGCCCGAGAGCCCC GCCTGCAGGCGGTGTAGATACATGTAGATACTGTAGATACTGTAGATACCGCCCCGGCGC CGACTTGATAAACGGTTTCGCCTCTTTTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_080647 unedited
GGGTTACCATTTGNTAATACGACTCACTATAGGGCGGCCGCGATTCAGATCTGGTACCAT GCACTTCAGCACCGTCACCAGGGACATGGAAGCCTTCACGGCCAGCAGCCTGAGCAGCCT GGGGGCCGCGGGGGGCTTCCCGGGCGCCGCGTCGCCCGGCGCCGACCCGTACGGCCCGCG CGAGCCCCCGCCGCCGCCGCGCTACGACCCGTGCGCCGCCGCCGCCCCCGGCGCCCCGGG TCCGCCGCCGCCGCCGCACGCCTACCCGTTTGCGCCGGCCGCCGGGGCCGCCACCAGCGC CGCCGCCGAGCCCGAGGGCCCCGGGGCCAGCTGCGCGGCCGCAGCCAAGGCGCCGGTGAA GAAGAACGCGAAGGTGGCCGGTGTGAGCGTGCAGCTAGAGATGAAGGCGCTGTGGGACGA GTTCAACCAGCTGGGCACCGAGATGATCGTCACCAAGGCCGGCAGGCGGATGTTTCCCAC CTTCCAAGTGAAGCTCTTCGGCATGGATCCCATGGCCGACTATATGCTGCTCATGGACTT CGTGCCGGTGGACGATAAGCGCTACCGGTCCCCCTCCACAGCTCCTCCTGGCTGGTGGCG GGAATGCCGACCCTGGCACGCCAGGCCCGGTGCCCTACCACCCGGACTTCGCTGGCAAGG GCGCGCATGGGATGAAGCAAATGTGGTCTTCACAAGCTCAAGCGGACCACAACCTTATGG ACAACAACGGCCACATATCTCGAATTCAAGCCCAATTCCCACCCCCTTTCCCGTGGTCTA TGGGGACCCCCCAAAATAGCCAGAATATGCCGAGGAGAAATTAAACCCTTTGTCTCAAGG AAACCATTTAACCGGGGACTGGCCTCCAAAACCTTGGATTCCCCCCCTTAATTGGCCGCA ATCC >OriGene 3' read for NM_080647 unedited
ACATGGNGATGGCACTTCAGGCCAGGAGGCACTGGGGAGGGTCACAGGGTGCCACCCGGG ATCTGTTAGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTT TTTTTTTTTTTTTCCAAAAGAGGCGAAACCGTTTATCAAGTCGGCGCCGGGGCGGTATCT ACAGTATCTACAGTATCTACATGTATCTACACCGCCTGCAGGCGGGGCTCTCGGGCTGTC TACACTGCAACTGCCGGCCGGGCCGCGGGCGACGCGGTCTCGGGGAGAACAATAAATATC ACTTCCTTCCGCCTCCGACCGGGCGCTTTGGCACTGGCGGGCGGGGACCCCCTTGGCCCT CGGGGCCGGGGAAGGACCCGCGGTGGCTCCAGGGACTGGGGAACCGGATACTTCGATAGC CCAAGGGGCTGGGGGTGGCGAGGGGGCCCCCATGGCTTCNAGGCTGGGGAAGGGGAGAGC CGCGGTGGCCCCTGGGGCTGGGGGAACGTATTCCTTGCTTGCCCTTGGGGCAGGGTGGCC GGGCCCGGCGAACTTCGGGGCTGTGCAGGACCGGGGCGGGAGCGCGACAGGGCCCGTGTT ATCTGGGGCAATAGTCGTAGGAGCCGGGCGGCGCGGCTCCGGCCGACGAGTACATGTTGG CGGCCGCGGCAGCTGCGGCAGCGGCGGCGGCGGCCGCGGCGGCTGGACTCACGGNGTGGT GGTGGTGGTGCGGATGCCCGTGCGGGTGGTAGCCGTGGCCACGCAGGCCGGGCAGCGGGT AGGGCGCCCGCCCGCTCTTTGCCCCAAGATAGTGGTCGTAGGCCGCCGCCGGATTTTTTA GGGGTGGTGGTGCAACGGCTTCCATTGCCCGGGCGGCTCCAGCCCCACTTGGGGTTCCGG GGACTGGGCCGG |
| Restriction Sites | Please inquire |
| ACCN | NM_080647 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There is 2 nucleotide difference between the OriGene clone and the NCBI reference ORF. These result in the substitution of 1 aa and deletion of 1 aa. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_080647.1, NP_542378.1 |
| RefSeq Size | 2082 bp |
| RefSeq ORF | 1488 bp |
| Locus ID | 6899 |
| UniProt ID | O43435 |
| Protein Families | Transcription Factors |
| Gene Summary | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (C) encodes the longest isoform (C) with the same N-terminal 336 aa, but an unique C-terminus with respect to isoforms A and B. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Novel TBX1 loss-of-function mutation causes isolated conotruncal heart defects in Chinese patients without 22q11.2 deletion
,Xu, YJ;Chen, S;Zhang, J;Fang, SH;Guo, QQ;Wang, J;Fu, QH;Li, F;Xu, R;Sun, K;,
BMC Med. Genet. July 2014
,PubMed ID 24998776
[TBX1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216204 | TBX1 (Myc-DDK-tagged)-Human T-box 1 (TBX1), transcript variant C |
CNY 3,656.00 |
|
| RC216204L1 | Lenti ORF clone of Human T-box 1 (TBX1), transcript variant C, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC216204L2 | Lenti ORF clone of Human T-box 1 (TBX1), transcript variant C, mGFP tagged |
CNY 5,890.00 |
|
| RC216204L3 | Lenti ORF clone of Human T-box 1 (TBX1), transcript variant C, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC216204L4 | Lenti ORF clone of Human T-box 1 (TBX1), transcript variant C, mGFP tagged |
CNY 5,890.00 |
|
| RG216204 | TBX1 (tGFP-tagged) - Human T-box 1 (TBX1), transcript variant C |
CNY 4,370.00 |
