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NALP1 (NLRP1) (NM_033004) Human Untagged Clone
CAT＃: SC308738
NLRP1 (untagged)-Human NLR family, pyrin domain containing 1 (NLRP1), transcript variant 1
CNY 10,088.00
| Cited in 1 publication. |
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AIADK; CARD7; CIDED; CLR17.1; DEFCAP; DEFCAP-L/S; JRRP; MSPC; NAC; NALP1; PP1044; SLEV1; VAMAS1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_033004 edited
GGTAAGAGCCAAGGCAAAGGACAGCACTGTTCTCTGCCTGCCTGATACCCTCACCACCTG GGAACATCCCCCAGACACCCTCTTAACTCCGGGACAGAGATGGCTGGCGGAGCCTGGGGC CGCCTGGCCTGTTACTTGGAGTTCCTGAAGAAGGAGGAGCTGAAGGAGTTCCAGCTTCTG CTCGCCAATAAAGCGCACTCCAGGAGCTCTTCGGGTGAGACACCCGCTCAGCCAGAGAAG ACGAGTGGCATGGAGGTGGCCTCGTACCTGGTGGCTCAGTATGGGGAGCAGCGGGCCTGG GACCTAGCCCTCCATACCTGGGAGCAGATGGGGCTGAGGTCACTGTGCGCCCAAGCCCAG GAAGGGGCAGGCCACTCTCCCTCATTCCCCTACAGCCCAAGTGAACCCCACCTGGGGTCT CCCAGCCAACCCACCTCCACCGCAGTGCTAATGCCCTGGATCCATGAATTGCCGGCGGGG TGCACCCAGGGCTCAGAGAGAAGGGTTTTGAGACAGCTGCCTGACACATCTGGACGCCGC TGGAGAGAAATCTCTGCCTCACTCCTCTACCAAGCTCTTCCAAGCTCCCCAGACCATGAG TCTCCAAGCCAGGAGTCACCCAACGCCCCCACATCCACAGCAGTGCTGGGGAGCTGGGGA TCCCCACCTCAGCCCAGCCTAGCACCCAGAGAGCAGGAGGCTCCTGGGACCCAATGGCCT CTGGATGAAACGTCAGGAATTTACTACACAGAAATCAGAGAAAGAGAGAGAGAGAAATCA GAGAAAGGCAGGCCCCCATGGGCAGCGGTGGTAGGAACGCCCCCACAGGCGCACACCAGC CTACAGCCCCACCACCACCCATGGGAGCCTTCTGTGAGAGAGAGCCTCTGTTCCACATGG CCCTGGAAAAATGAGGATTTTAACCAAAAATTCACACAGCTGCTACTTCTACAAAGACCT CACCCCAGAAGCCAAGATCCCCTGGTCAAGAGAAGCTGGCCTGATTATGTGGAGGAGAAT CGAGGACATTTAATTGAGATCAGAGACTTATTTGGCCCAGGCCTGGATACCCAAGAACCT CGCATAGTCATACTGCAGGGGGCTGCTGGAATTGGGAAGTCAACACTGGCCAGGCAGGTG AAGGAAGCCTGGGGGAGAGGCCAGCTGTATGGGGACCGCTTCCAGCATGTCTTCTACTTC AGCTGCAGAGAGCTGGCCCAGTCCAAGGTGGTGAGTCTCGCTGAGCTCATCGGAAAAGAT GGGACAGCCACTCCGGCTCCCATTAGACAGATCCTGTCTAGGCCAGAGCGGCTGCTCTTC ATCCTCGATGGTGTAGATGAGCCAGGATGGGTCTTGCAGGAGCCGAGTTCTGAGCTCTGT CTGCACTGGAGCCAGCCACAGCCGGCGGATGCACTGCTGGGCAGTTTGCTGGGGAAAACT ATACTTCCCGAGGCATCCTTCCTGATCACGGCTCGGACCACAGCTCTGCAGAACCTCATT CCTTCTTTGGAGCAGGCACGTTGGGTAGAGGTCCTGGGGTTCTCTGAGTCCAGCAGGAAG GAATATTTCTACAGATATTTCACAGATGAAAGGCAAGCAATTAGAGCCTTTAGGTTGGTC AAATCAAACAAAGAGCTCTGGGCCCTGTGTCTTGTGCCCTGGGTGTCCTGGCTGGCCTGC ACTTGCCTGATGCAGCAGATGAAGCGGAAGGAAAAACTCACACTGACTTCCAAGACCACC ACAACCCTCTGTCTACATTACCTTGCCCAGGCTCTCCAAGCTCAGCCATTGGGACCCCAG CTCAGAGACCTCTGCTCTCTGGCTGCTGAGGGCATCTGGCAAAAAAAGACCCTTTTCAGT CCAGATGACCTCAGGAAGCATGGGTTAGATGGGGCCATCATCTCCACCTTCTTGAAGATG GGTATTCTTCAAGAGCACCCCATCCCTCTGAGCTACAGCTTCATTCACCTCTGTTTCCAA GAGTTCTTTGCAGCAATGTCCTATGTCTTGGAGGATGAGAAGGGGAGAGGTAAACATTCT AATTGCATCATAGATTTGGAAAAGACGCTAGAAGCATATGGAATACATGGCCTGTTTGGG GCATCAACCACACGTTTCCTATTGGGCCTGTTAAGTGATGAGGGGGAGAGAGAGATGGAG AACATCTTTCACTGCCGGCTGTCTCAGGGGAGGAACCTGATGCAGTGGGTCCCGTCCCTG CAGCTGCTGCTGCAGCCACACTCTCTGGAGTCCCTCCACTGCTTGTACGAGACTCGGAAC AAAACGTTCCTGACACAAGTGATGGCCCATTTCGAAGAAATGGGCATGTGTGTAGAAACA GACATGGAGCTCTTAGTGTGCACTTTCTGCATTAAATTCAGCCGCCACGTGAAGAAGCTT CAGCTGATTGAGGGCAGGCAGCACAGATCAACATGGAGCCCCACCATGGTAGTCCTGTTC AGGTGGGTCCCAGTCACAGATGCCTATTGGCAGATTCTCTTCTCCGTCCTCAAGGTCACC AGAAACCTGAAGGAGCTGGACCTAAGTGGAAACTCGCTGAGCCACTCTGCAGTGAAGAGT CTTTGTAAGACCCTGAGACGCCCTCGCTGCCTCCTGGAGACCCTGCGGTTGGCTGGCTGT GGCCTCACAGCTGAGGACTGCAAGGACCTTGCCTTTGGGCTGAGAGCCAACCAGACCCTG ACCGAGCTGGACCTGAGCTTCAATGTGCTCACGGATGCTGGAGCCAAACACCTTTGCCAG AGACTGAGACAGCCGAGCTGCAAGCTACAGCGACTGCAGCTGGTCAGCTGTGGCCTCACG TCTGACTGCTGCCAGGACCTGGCCTCTGTGCTTAGTGCCAGCCCCAGCCTGAAGGAGCTA GACCTGCAGCAGAACAACCTGGATGACGTTGGCGTGCGACTGCTCTGTGAGGGGCTCAGG CATCCTGCCTGCAAACTCATACGCCTGGGGCTGGACCAGACAACTCTGAGTGATGAGATG AGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTGCTCATCTTCAGCAGACGG AAACCAAGTGTGATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACA TCCTCACTCAAGCGGCAGAGACTCGGATCAGAGAGGGCGGCTTCCCATGTTGCTCAGGCT AATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCTGAGATTGCAGAGGAAAGC TCCCCAGAGGTAGTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGAC CTGCATACGAAGCCTTTGGGGACTGACGATGACTTCTGGGGCCCCACGGGGCCTGTGGCT ACTGAGGTAGTTGACAAAGAAAAGAACTTGTACCGAGTTCACTTCCCTGTAGCTGGCTCC TACCGCTGGCCCAACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATT GAATTCTGTGTGTGGGACCAGTTCCTGGGTGAGATCAACCCACAGCACAGCTGGATGGTG GCAGGGCCTCTGCTGGACATCAAGGCTGAGCCTGGAGCTGTGGAAGCTGTGCACCTCCCT CACTTTGTGGCTCTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTT AAAGAGGAGGGGATGCTCCTGGAGAAGCCAGCCAGGGTGGAGCTGCATCACATAGTTCTG GAAAACCCCAGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATGATCCATAATGCCCTGCGC TTCATTCCCGTCACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACC TTCCACCTCTACCTGATCCCAAGTGACTGCTCCATTCGGAAGGCCATAGATGATCTAGAA ATGAAATTCCAGTTTGTGCGAATCCACAAGCCACCCCCGCTGACCCCACTTTATATGGGC TGTCGTTACACTGTGTCTGGGTCTGGTTCAGGGATGCTGGAAATACTCCCCAAGGAACTG GAGCTCTGCTATCGAAGCCCTGGAGAAGACCAGCTGTTCTCGGAGTTCTACGTTGGCCAC TTGGGATCAGGGATCAGGCTGCAAGTGAAAGACAAGAAAGATGAGACTCTGGTGTGGGAG GCCTTGGTGAAACCAGGAGATCTCATGCCTGCAACTACTCTGATCCCTCCAGCCCGCATA GCCGTACCTTCACCTCTGGATGCCCCGCAGTTGCTGCACTTTGTGGACCAGTATCGAGAG CAGCTGATAGCCCGAGTGACATCGGTGGAGGTTGTCTTGGACAAACTGCATGGACAGGTG CTGAGCCAGGAGCAGTACGAGAGGGTGCTGGCTGAGAACACGAGGCCCAGCCAGATGCGG AAGCTGTTCAGCTTGAGCCAGTCCTGGGACCGGAAGTGCAAAGATGGACTCTACCAAGCC CTGAAGGAGACCCATCCTCACCTCATTATGGAACTCTGGGAGAAGGGCAGCAAAAAGGGA CTCCTGCCACTCAGCAGCTGAAGTATCAACACCAGCCCTTGACCCTTGAGTCCTGGCTTT GGCTGACCCTTCTTTGGGTCTCAGTTTCTTTCTCTGCAAACAAGTTGCCATCTGGTTTGC C >OriGene 5' read for NM_033004 unedited
NGAGTTCAAAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGACTT CTTCCAGTGTCTTGCAGGCCCCTCTGGGCTCCTCCCTCCCCTGGCTTTTCCTACCACTCC CCCTCTATCGGCGTCTATCTGTAGGTGCCCTGGGATTTATAAAACTGGGTTCCGAATGCT GAATAAGAGACGGTAAGAGCCAAGGCAAAGGACAGCACTGTTCTCTGCCTGCCTGATACC CTCACCACCTGGGAACATCCCCCAGACACCCTCTTAACTCCGGGACAGAGATGGCTGGCG GAGCCTGGGGCCGCCTGGCCTGTTACTTGGAGTTCCTGAAGAAGGAGGAGCTGAAGGAGT TCCAGCTTCTGCTCGCCAATAAAGCGCACTCCAGGAGCTCTTCGGGTGAGACACCCGCTC AGCCAGAGAAGACGAGTGGCATGGAGGTGGCCTCGTACCTGGTGGCTCAGTATGGGGAGC AGCGGGCCTGGGACCTAGCCCTCCATACCTGGGAGCAGATGGGGCTGAGGTCACTGTGCG CCCAAGCCCAGGAAGGGGCAGGCCACTCTCCCTCATTCCCCTACAGCCCAAGTGAACCCC ACCTGGGGTCTCCCAGCCAACCCACCTCCACCGCAGTGCTAATGCCCTGGATCCATGAAT TGCCGGCGGGGTGCACCCAGGGCTCAGAGAGAAGGGTTTTGAGACAGCTGCCTGACACAT CTGGACGCCGCTGGAGAGAAATCTCTGCCTCACTCCTCTACCAAGCTCTTCCAAGCTCCC CAGACCATGAGTCTCCAAGCCAGGAGTCACCCAACGCCCCCACATCCACAGCAGTGCTGG GGAGCTGGGGATCCCCACCTCAGCCCAGCCTAGCACCCAGAGAGCAG >OriGene 3' read for NM_033004 unedited
TTTTTCCCCGTGCTCACGCAGGAGAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGA TCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTT TTTTTTTTCTAAAAGAGCTGTGATACTCCTTTATTTTCTGAATAAACTTCCTTCCACTTT ACTCTGTTGGCTTGCTCTTGTAGATCTTCCTGTACAAAGCCAAGAATCCACGTGGCCTCC CACGCTGAACCCCAATTTTGGGGCTCACCCTGTGACACAGCCAGAGGCAAATGGTTCCAT GTCCCTCCTATTCCTCTTTGCGCCTGGATGGGATCCGGAGGGCTCTAGGCTTGGCTGCTG TGGCCACCAAATGAGGCTCTATGAGGTCTGCAGGGGTCTTGCCAGCTCCAGATGGACATT CCCTGAGATGCTGTTAGGCCACCTGGACTGGGGCCCCCTGTGGCATCCCTGGCATGGACA CATAATGCCCAGCAAAGGCATCATCAAAGTTCCATTACTTTAGTGCTGGAAGGCAAACCA AATGGCAACTTGTTTGCAGAGAAAGAAACTGAGACCCAAAGAAGGGTCAGCCAAAGCCAG GACTCAAGGGTCAAGGGCTGGTGTTGATACTTCAGCTGCTGAGTGGCAGGAGTCCCTTTT TGCTGCCCTTCTCCCAGAGTTCCATAATGAGGTGAGGATGGGTCTCCTTCAGGGCTTGGT AGAGTCCATCTTTGCACTTCCGGTCCCAGGACTGGCTCAAGCTGAACAGCTTCCGCATCT GGCTGGGCCTCGTGTTCTCAGCCAGCACCCTCTCGTACTGCTCCTGGCTCAGCACCTGTC CATGCAGTTTGTCCAAAACAACCTCCACCGATGTCACTCGGGCTATCAGCTGCTCTCGAT ACTGGTCCACAAAGTGCAGCAACTGCGGGGCATCCAAAGGTTGAAGTACGGCTATGCGGG GCTGGAGGGATCAAATTAATTGCAGGCATGAAATCTCCTGGGTTTACCCAGGCCTCCCCA CCCAAAATCTCATCTTTCTTGTCTTTCATTTCAGCCCGAATCCTGATTCCAATGGGCCAA CTTAAAATCCCCAAAAAGCCTGGCTTTCCCAGGGCTTCAATACAAAAACCCCTTTCCTGG GGAAATATTCCCCTTCCCGAAACAAAACCAAAACATGTAAGAACCCCCAAAAAAATGGGG TACCGGGGGTGGCTTGGAATCCCCAAACGGAATTTTTTTTAAATTTTTTGGGCTTCAAGG AAACCT |
| Restriction Sites | Please inquire |
| ACCN | NM_033004 |
| Insert Size | 4600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033004.2, NP_127497.1 |
| RefSeq Size | 5617 bp |
| RefSeq ORF | 4422 bp |
| Locus ID | 22861 |
| UniProt ID | Q9C000 |
| Protein Families | Druggable Genome |
| Protein Pathways | NOD-like receptor signaling pathway |
| Gene Summary | This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1ß processing via the NLRP1 inflammasome
,Cecilia B. Levandowski, Christina M. Mailloux, Tracey M. Ferrara, Katherine Gowan, Songtao Ben, Ying Jin, Kimberly K. McFann, Paulene J. Holland, Pamela R. Fain, Charles A. Dinarello, and Richard A. Spritz,
PNAS, Feb 2013; 110: 2952 - 2956.
[NLRP1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216481 | NLRP1 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 1 (NLRP1), transcript variant 1 |
CNY 10,080.00 |
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| RC216481L1 | Lenti ORF clone of Human NLR family, pyrin domain containing 1 (NLRP1), transcript variant 1, Myc-DDK-tagged |
CNY 12,480.00 |
|
| RC216481L2 | Lenti ORF clone of Human NLR family, pyrin domain containing 1 (NLRP1), transcript variant 1, mGFP tagged |
CNY 16,630.00 |
|
| RC216481L3 | Lenti ORF clone of Human NLR family, pyrin domain containing 1 (NLRP1), transcript variant 1, Myc-DDK-tagged |
CNY 12,480.00 |
|
| RC216481L4 | Lenti ORF clone of Human NLR family, pyrin domain containing 1 (NLRP1), transcript variant 1, mGFP tagged |
CNY 16,630.00 |
|
| RG216481 | NLRP1 (tGFP-tagged) - Human NLR family, pyrin domain containing 1 (NLRP1), transcript variant 1 |
CNY 11,680.00 |
