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CSB (ERCC6) (NM_000124) Human Untagged Clone
CAT＃: SC309065
ERCC6 (untagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6)
CNY 10,450.00
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARMD5; CKN2; COFS; COFS1; CSB; CSB-PGBD3; POF11; RAD26; UVSS1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC309065 representing NM_000124.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCCAAATGAGGGAATCCCCCACTCAAGTCAAACTCAGGAGCAAGACTGTTTACAGAGTCAACCTGTC AGTAATAATGAAGAAATGGCAATCAAGCAAGAAAGTGGTGGTGATGGGGAGGTGGAGGAGTACCTCTCC TTTCGTTCTGTGGGTGACGGGCTGTCCACCTCTGCTGTGGGGTGCGCATCAGCAGCTCCGAGGAGAGGG CCAGCCCTGCTGCACATCGACCGACATCAGATCCAGGCAGTAGAGCCTAGCGCCCAGGCCCTTGAGCTG CAGGGTTTGGGTGTGGACGTCTATGACCAGGACGTGCTGGAACAGGGAGTGCTTCAGCAGGTGGACAAT GCCATCCATGAGGCCAGCCGTGCCTCCCAGCTCGTTGACGTGGAGAAGGAGTATCGGTCGGTCCTGGAT GACCTCACGTCATGTACGACATCCCTAAGGCAAATCAATAAAATTATTGAACAGCTTAGCCCTCAAGCT GCCACCAGCAGAGACATCAACAGGAAACTAGATTCTGTAAAACGACAGAAGTATAATAAGGAACAACAG CTAAAAAAGATCACTGCAAAACAAAAGCATCTCCAGGCCATCCTTGGAGGAGCAGAGGTGAAAATTGAA CTAGATCACGCCAGTCTGGAGGAGGATGCAGAGCCGGGGCCATCCAGTCTTGGCAGCATGCTCATGCCT GTCCAGGAGACTGCCTGGGAAGAGCTCATCCGCACTGGCCAGATGACACCTTTTGGTACCCAGATCCCT CAGAAACAGGAGAAAAAGCCCAGAAAAATCATGCTTAATGAAGCATCAGGCTTCGAAAAGTATTTGGCA GATCAAGCAAAACTGTCTTTTGAAAGGAAGAAGCAAGGTTGTAATAAAAGAGCAGCTAGAAAAGCTCCA GCCCCAGTCACGCCTCCAGCCCCAGTGCAAAATAAAAACAAACCAAACAAGAAAGCCAGAGTTCTGTCC AAAAAAGAGGAGCGTTTGAAAAAGCACATCAAGAAACTCCAGAAGAGGGCTTTGCAGTTCCAGGGGAAA GTGGGATTGCCAAAGGCAAGGAGACCTTGGGAGTCAGACATGAGGCCAGAGGCAGAGGGAGACTCTGAG GGTGAAGAGTCTGAGTATTTCCCCACAGAGGAGGAGGAAGAGGAGGAAGATGACGAGGTGGAGGGGGCA GAGGCGGACCTGTCTGGAGATGGTACTGACTATGAGCTGAAGCCTCTGCCCAAGGGCGGGAAACGGCAG AAGAAAGTGCCAGTGCAGGAGATTGATGATGACTTTTTCCCAAGTTCTGGGGAAGAAGCTGAAGCTGCT TCTGTAGGAGAAGGAGGAGGAGGAGGTCGGAAAGTGGGAAGATACCGAGATGATGGAGATGAAGATTAT TATAAGCAGCGGTTAAGGAGATGGAATAAACTGAGACTGCAGGACAAAGAGAAACGTCTGAAGCTGGAG GACGATTCTGAGGAAAGTGATGCTGAATTTGACGAAGGTTTTAAAGTGCCAGGTTTTCTGTTCAAAAAG CTTTTTAAGTACCAGCAGACAGGTGTTAGGTGGCTGTGGGAATTGCACTGCCAGCAGGCAGGAGGAATT CTGGGAGATGAAATGGGATTGGGCAAGACCATCCAGATAATTGCCTTCTTGGCAGGTCTGAGCTACAGC AAGATCAGGACTCGTGGTTCAAATTACAGGTTTGAGGGGTTGGGTCCAACTGTAATTGTCTGTCCAACA ACAGTGATGCATCAGTGGGTGAAGGAATTTCACACGTGGTGGCCTCCGTTCAGAGTGGCAATTCTACAT GAAACCGGTTCCTATACCCACAAAAAGGAGAAACTAATTCGAGATGTTGCTCATTGTCATGGAATTTTG ATCACATCTTACTCCTACATTCGATTGATGCAGGATGACATTAGCAGGTATGACTGGCACTATGTGATC TTGGACGAAGGACACAAAATTCGAAATCCAAATGCTGCTGTCACCCTTGCTTGCAAACAGTTTCGCACC CCTCATCGGATCATTCTGTCTGGCTCACCGATGCAAAATAACCTCCGAGAGCTGTGGTCGCTCTTTGAC TTCATCTTCCCGGGAAAGTTAGGCACGTTGCCTGTGTTTATGGAGCAGTTCTCCGTCCCCATCACCATG GGGGGATATTCAAATGCTTCCCCAGTACAGGTCAAAACTGCTTACAAGTGTGCATGTGTCTTACGAGAT ACCATAAATCCATACCTACTGCGGAGAATGAAGTCAGATGTCAAGATGAGCCTTTCTTTGCCAGATAAA AATGAACAGGTCTTATTTTGCCGTCTTACAGATGAGCAGCATAAAGTCTACCAAAATTTCGTTGATTCC AAAGAAGTTTACAGGATTCTCAATGGAGAGATGCAGATTTTCTCCGGACTTATAGCCCTAAGAAAAATT TGCAACCACCCTGATCTCTTTTCTGGAGGTCCCAAGAATCTCAAAGGTCTTCCTGATGATGAACTAGAA GAAGATCAGTTTGGGTACTGGAAACGTTCTGGGAAAATGATTGTTGTTGAGTCTTTGTTGAAAATATGG CACAAGCAGGGTCAGCGAGTATTGCTGTTTTCTCAGTCAAGGCAGATGCTGGACATACTTGAAGTATTC CTTAGAGCCCAAAAGTATACCTATCTCAAGATGGATGGTACCACTACAATAGCTTCAAGACAGCCACTG ATTACGAGATACAATGAGGACACATCCATATTTGTGTTTCTTCTGACCACGCGGGTGGGCGGCTTAGGT GTCAACCTGACGGGGGCAAACAGAGTTGTCATCTATGACCCAGACTGGAACCCAAGCACGGACACGCAG GCCCGGGAGCGAGCATGGAGAATAGGCCAGAAGAAGCAAGTGACTGTGTACAGGCTCCTGACTGCGGGC ACCATTGAAGAAAAGATCTACCACCGACAAATCTTCAAGCAGTTTTTGACAAATAGAGTGCTAAAAGAC CCAAAACAAAGGCGGTTTTTCAAATCCAATGATCTCTATGAGCTATTTACTCTGACTAGTCCTGATGCA TCCCAGAGCACTGAAACAAGTGCAATTTTTGCAGGAACTGGATCAGATGTTCAGACACCCAAATGCCAT CTAAAAAGAAGGATTCAACCAGCCTTTGGAGCAGACCATGATGTTCCAAAACGCAAGAAGTTCCCTGCT TCTAACATATCTGTAAATGATGCCACATCATCTGAAGAGAAATCTGAGGCTAAAGGAGCTGAAGTAAAT GCAGTAACTTCTAATCGAAGTGATCCTTTGAAAGATGACCCTCACATGAGTAGTAATGTAACTAGCAAT GATAGGCTTGGAGAAGAGACAAATGCAGTATCTGGACCAGAAGAGTTGTCAGTGATTAGTGGAAATGGG GAATGTTCAAATTCTTCAGGAACAGGCAAAACTTCTATGCCATCTGGTGATGAAAGCATTGATGAAAAG TTAGGTCTTTCTTACAAAAGAGAAAGACCCAGCCAGGCTCAAACAGAAGCTTTTTGGGAGAATAAACAA ATGGAAAATAATTTTTATAAGCACAAGTCAAAAACAAAACATCATAGTGTGGCAGAAGAAGAGACCCTG GAGAAACATCTGAGACCAAAGCAAAAGCCTAAGAACTCTAAGCATTGCAGAGACGCCAAGTTTGAAGGA ACTCGAATTCCACACCTGGTGAAGAAAAGGCGTTACCAGAAGCAAGACAGTGAAAACAAGAGTGAGGCC AAGGAACAGAGCAATGACGATTATGTTTTGGAAAAGCTTTTCAAAAAATCAGTTGGCGTGCACAGTGTC ATGAAGCACGATGCCATCATGGATGGAGCCAGCCCAGATTATGTACTGGTGGAGGCAGAAGCCAACCGA GTGGCCCAGGATGCCCTGAAAGCACTGAGGCTCTCTCGTCAGCGGTGTCTGGGAGCAGTGTCTGGTGTT CCCACCTGGACTGGCCACAGGGGGATTTCTGGTGCACCAGCAGGAAAAAAGAGTAGATTTGGTAAGAAA AGGAATTCTAACTTCTCTGTGCAGCATCCTTCATCAACATCTCCAACAGAGAAGTGCCAGGATGGCATC ATGAAAAAGGAGGGAAAAGATAATGTCCCTGAGCATTTTAGTGGAAGAGCAGAAGATGCAGACTCTTCA TCCGGGCCCCTCGCTTCCTCCTCACTCTTGGCTAAAATGAGAGCTAGAAACCACCTGATTCTGCCAGAG CGTTTAGAAAGTGAAAGCGGGCACCTGCAGGAAGCTTCTGCCCTGCTGCCCACCACAGAACACGATGAC CTTCTGGTGGAGATGAGAAACTTCATCGCTTTCCAGGCCCACACTGATGGCCAGGCCAGCACCAGGGAG ATACTGCAGGAGTTTGAATCCAAGTTATCTGCATCACAGTCTTGTGTCTTCCGAGAACTATTGAGAAAT CTGTGCACTTTCCATAGAACTTCTGGTGGTGAAGGAATTTGGAAACTCAAGCCAGAATACTGCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_000124 |
| Insert Size | 4482 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000124.3 |
| RefSeq Size | 8993 bp |
| RefSeq ORF | 4482 bp |
| Locus ID | 2074 |
| UniProt ID | Q03468 |
| Domains | SNF2_N, DEAD, helicase_C |
| Protein Families | Druggable Genome |
| Protein Pathways | Nucleotide excision repair |
| MW | 168.4 kDa |
| Gene Summary | This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (3) represents the longest transcript and encodes the longer protein (isoform 2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219020 | ERCC6 (Myc-DDK-tagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6) |
CNY 15,320.00 |
|
| RC219020L1 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6), Myc-DDK-tagged |
CNY 17,720.00 |
|
| RC219020L2 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6), mGFP tagged |
CNY 16,820.00 |
|
| RC219020L3 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6), Myc-DDK-tagged |
CNY 16,820.00 |
|
| RC219020L4 | Lenti ORF clone of Human excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6), mGFP tagged |
CNY 17,720.00 |
|
| RG219020 | ERCC6 (tGFP-tagged) - Human excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6) |
CNY 16,920.00 |
