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delta Sarcoglycan (SGCD) (NM_172244) Human Untagged Clone
CAT＃: SC309561
SGCD (untagged)-Human sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (SGCD), transcript variant 2
CNY 3,990.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 3,340.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 35DAG; CMD1L; DAGD; LGMDR6; SG-delta; SGCDP; SGD |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_172244 edited
GACAAGAGAGAGACATTACTGCCGGGAGTGTTGAGTGAAGGGACCAGGTGGAGATGATGC CTCAGGAGCAGTACACTCACCACCGGAGCACCATGCCTGGCTCTGTGGGGCCACAGGTAT ACAAGGTGGGGATTTATGGCTGGCGGAAACGATGCCTGTATTTCTTTGTCCTGCTCCTCA TGATTTTAATACTGGTGAACTTGGCCATGACCATCTGGATTCTCAAAGTCATGAACTTCA CAATTGATGGAATGGGAAACCTGAGGATCACAGAAAAAGGTCTAAAGCTAGAAGGAGACT CTGAATTCTTACAACCTCTCTACGCCAAAGAAATCCAGTCCCAACCAGGTAATGCCCTGT ACTTCAAGTCTGCCAGAAATGTTACAGTGAACATTCTCAATGACCAGACTAAAGTGCTAA CTCAGCTTATAACAGGTCCAAAAGCCGTAGAAGCTTATGGTAAAAAATTTGAGGTAAAAA CTGTTTCTGGAAAATTGCTCTTCTCTGCAGACAATAATGAAGTGGTAGTAGGAGCTGAAA GATTACGAGTTTTAGGAGCGGAGGGCACAGTGTTCCCTAAATCTATAGAAACACCTAATG TCAGGGCAGACCCCTTCAAAGAACTAAGGTTGGAGTCCCCAACCCGGTCTCTAGTGATGG AGGCCCCAAAAGGAGTGGAAATCAATGCAGAAGCTGGCAATATGGAAGCCACCTGCAGGA CAGAGCTGAGACTGGAATCCAAAGATGGAGAGGTGAGGGATGAGAAGGACAGAAGTTCAA AGAGCTACAGCTTCAACAGGCCAACCCTTCCCATAACTGGTTGACCTCGGAGTTGGATCC TACAGTGTATCAACAAAAGGAGCCAAGCAGGTTTTATTTCTGAAACAATTAATTGAGCAG CATGATTATAAGCCAAACCCACAATCCATCAAAGTGATGATTTCTTATTTGTAAAATGCA GAGATAATGGCATGTATTCCAAGTACAGAATTATATGACCATGAAAATGAATGCTATTTT CAAATTCTCTCTTGTCACCTTAAAATAAGATTTTGTTAGCCAACATAATTAAGCTGTATA TATTATACACATCTGGCTCAAGATGAACTTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_172244 |
| Insert Size | 1100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_172244.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_172244.2, NP_758447.1 |
| RefSeq Size | 1576 bp |
| RefSeq ORF | 771 bp |
| Locus ID | 6444 |
| UniProt ID | Q92629 |
| Protein Families | Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis |
| Gene Summary | The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2, also known as SGCD2), contains an alternate 3' terminal exon compared to transcript variant 1. This results in a shorter isoform (2) with a distinct C-terminus compared to isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Genetic variation at the delta-sarcoglycan (SGCD) locus elevates heritable sympathetic nerve activity in human twin pairs
,null,
Journal of neurochemistry
,PubMed ID 23786442
[SGCD]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217866 | SGCD (Myc-DDK-tagged)-Human sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (SGCD), transcript variant 2 |
CNY 2,400.00 |
|
| RC217866L3 | Lenti ORF clone of Human sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (SGCD), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217866L4 | Lenti ORF clone of Human sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (SGCD), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG217866 | SGCD (tGFP-tagged) - Human sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) (SGCD), transcript variant 2 |
CNY 4,370.00 |
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