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ADAMTS18 (NM_199355) Human Untagged Clone
CAT＃: SC309941
ADAMTS18 (untagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 18 (ADAMTS18)
CNY 12,760.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADAMTS21; KNO2; MMCAT |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_199355, the custom clone sequence may differ by one or more nucleotides
ATGGAGTGCGCCCTCCTGCTCGCGTGTGCCTTCCCGGCTGCGGGTTCGGGCCCGCCGAGGGGCCTGGCGG GACTGGGGCGCGTGGCCAAGGCGCTCCAGCTGTGCTGCCTCTGCTGTGCGTCGGTCGCCGCGGCCTTAGC CAGTGACAGCAGCAGCGGCGCCAGCGGATTAAATGATGATTACGTCTTTGTCACGCCAGTAGAAGTAGAC TCAGCCGGGTCATATATTTCACACGACATTTTGCACAACGGCAGGAAAAAGCGATCGGCGCAGAATGCCA GAAGCTCCCTGCACTACCGATTTTCAGCATTTGGACAGGAACTGCACTTAGAACTTAAGCCCTCGGCGAT TTTGAGCAGTCACTTTATTGTCCAGGTACTTGGAAAAGATGGTGCTTCAGAGACTCAGAAACCCGAGGTG CAGCAATGCTTCTATCAGGGATTTATCAGAAATGACAGCTCCTCCTCTGTCGCTGTGTCTACGTGTGCTG GCTTGTCAGGTTTAATAAGGACACGAAAAAATGAATTCCTCATCTCGCCATTACCTCAGCTTCTGGCCCA GGAACACAACTACAGCTCCCCTGCGGGTCACCATCCTCACGTACTGTACAAAAGGACAGCAGAGGAGAAG ATCCAGCGGTACCGTGGCTACCCCGGCTCTGGCCGGAATTATCCTGGTTACTCCCCAAGTCACATTCCCC ATGCATCTCAGAGTCGAGAGACAGAGTATCACCATCGAAGGTTGCAAAAGCAGCATTTTTGTGGACGACG CAAGAAATATGCTCCCAAGCCTCCCACAGAGGACACCTATCTAAGGTTTGATGAATATGGGAGCTCTGGG CGACCCAGAAGATCAGCTGGAAAATCACAAAAGGGCCTCAATGTGGAAACCCTCGTGGTGGCAGACAAGA AAATGGTGGAAAAGCATGGCAAGGGAAATGTCACCACATACATTCTCACAGTAATGAACATGGTTTCTGG CCTATTTAAAGATGGGACTATTGGAAGTGACATAAACGTGGTTGTGGTGAGCCTAATTCTTCTGGAACAA GAACCTGGAGGATTATTGATCAACCATCATGCAGACCAGTCTCTGAATAGTTTTTGTCAATGGCAGTCTG CCCTCATTGGAAAGAATGGCAAGAGACATGATCATGCCATCTTACTAACAGGATTTGATATTTGTTCTTG GAAGAATGAACCATGTGACACTCTAGGGTTTGCCCCCATCAGTGGAATGTGCTCTAAGTACCGAAGTTGT ACCATCAATGAGGACACAGGACTTGGCCTTGCCTTCACCATCGCTCATGAGTCAGGGCACAACTTTGGTA TGATTCACGACGGAGAAGGGAATCCCTGCAGAAAGGCTGAAGGCAATATCATGTCTCCCACACTGACCGG AAACAATGGAGTGTTTTCATGGTCTTCCTGCAGCCGCCAGTATCTCAAGAAATTCCTCAGCACACCTCAG GCGGGGTGTCTAGTGGATGAGCCCAAGCAAGCAGGACAGTATAAATATCCGGACAAACTACCAGGACAGA TTTATGATGCTGACACACAGTGTAAATGGCAATTTGGAGCAAAAGCCAAGTTATGCAGCCTTGGTTTTGT GAAGGATATTTGCAAATCACTTTGGTGCCACCGAGTAGGCCACAGGTGTGAGACCAAGTTTATGCCCGCA GCAGAAGGGACCGTTTGTGGCTTGAGTATGTGGTGTCGGCAAGGCCAGTGCGTAAAGTTTGGGGAGCTCG GGCCCCGGCCCATCCACGGCCAGTGGTCCGCCTGGTCGAAGTGGTCAGAATGTTCCCGGACATGTGGTGG AGGAGTCAAGTTCCAGGAGAGACACTGCAATAACCCCAAGCCTCAGTATGGTGGCTTATTCTGTCCAGGT TCTAGCCGTATTTATCAGCTGTGCAATATTAACCCTTGCAATGAAAATAGCTTGGATTTTCGGGCTCAAC AGTGTGCAGAATATAACAGCAAACCTTTCCGTGGATGGTTCTACCAGTGGAAACCCTATACAAAAGTGGA AGAGGAAGATCGATGCAAACTGTACTGCAAGGCTGAGAACTTTGAATTTTTTTTTGCAATGTCCGGCAAA GTGAAAGATGGAACTCCCTGCTCCCCAAACAAAAATGATGTTTGTATTGACGGGGTTTGTGAACTAGTGG GATGTGATCATGAACTAGGCTCTAAAGCAGTTTCAGATGCTTGTGGCGTTTGCAAAGGTGATAATTCAAC TTGCAAGTTTTATAAAGGCCTGTACCTCAACCAGCATAAAGCAAATGAATATTATCCGGTGGTCCTCATT CCAGCTGGCGCCCGAAGCATCGAAATCCAGGAGCTGCAGGTTTCCTCCAGTTACCTCGCAGTTCGAAGCC TCAGTCAAAAGTATTACCTCACCGGGGGCTGGAGCATCGACTGGCCTGGGGAGTTCCCCTTCGCTGGGAC CACGTTTGAATACCAGCGCTCTTTCAACCGCCCGGAACGTCTGTACGCGCCAGGGCCCACAAATGAGACG CTGGTCTTTGAAATTCTGATGCAAGGCAAAAATCCAGGGATAGCTTGGAAGTATGCACTTCCCAAGGTCA TGAATGGAACTCCACCAGCCACAAAAAGACCTGCCTATACCTGGAGTATCGTGCAGTCAGAGTGCTCCGT CTCCTGTGGTGGAGGTTACATAAATGTAAAGGCCATTTGCTTGCGAGATCAAAATACTCAAGTCAATTCC TCATTCTGCAGTGCAAAAACCAAGCCAGTAACTGAGCCCAAAATCTGCAACGCTTTCTCCTGCCCGGCTT ACTGGATGCCAGGTGAATGGAGTACATGCAGCAAGGCCTGTGCTGGAGGCCAGCAGAGCCGAAAGATCCA GTGTGTGCAAAAGAAGCCCTTCCAAAAGGAGGAAGCAGTGTTGCATTCTCTCTGTCCAGTGAGCACACCC ACTCAGGTCCAAGCCTGCAACAGCCATGCCTGCCCTCCACAATGGAGCCTTGGACCCTGGTCTCAGTGTT CCAAGACCTGTGGACGAGGGGTGAGGAAGCGTGAACTCCTCTGCAAGGGCTCTGCCGCAGAAACCCTCCC CGAGAGCCAGTGTACCAGTCTCCCCAGACCTGAGCTGCAGGAGGGCTGTGTGCTTGGACGATGCCCCAAG AACAGCCGGCTACAGTGGGTCGCTTCTTCGTGGAGCGAGTGTTCTGCAACCTGTGGTTTGGGTGTGAGGA AGAGGGAGATGAAGTGCAGCGAGAAGGGCTTCCAGGGAAAGCTGATAACTTTCCCAGAGCGAAGATGCCG TAATATTAAGAAACCAAATCTGGACTTGGAAGAGACCTGCAACCGACGGGCTTGCCCAGCCCATCCAGTG TACAACATGGTAGCTGGATGGTATTCATTGCCGTGGCAGCAGTGCACAGTCACCTGTGGGGGAGGGGTCC AGACCCGGTCAGTCCACTGTGTTCAGCAAGGCCGGCCTTCCTCAAGTTGTCTGCTCCATCAGAAACCTCC GGTGCTACGAGCCTGTAATACAAACTTCTGTCCAGCTCCTGAAAAGAGAGAGGATCCATCCTGCGTAGAT TTCTTCAACTGGTGTCACCTAGTTCCTCAGCATGGTGTCTGCAACCACAAGTTTTACGGAAAACAATGCT GCAAGTCATGCACAAGGAAGATCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_199355 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_199355.1, NP_955387.1 |
| RefSeq Size | 5510 bp |
| RefSeq ORF | 3666 bp |
| Locus ID | 170692 |
| UniProt ID | Q8TE60 |
| Protein Families | Protease, Secreted Protein |
| Gene Summary | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in this gene may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients. [provided by RefSeq, May 2016] Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209192 | ADAMTS18 (Myc-DDK-tagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 18 (ADAMTS18) |
CNY 12,752.00 |
|
| RC209192L3 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 18 (ADAMTS18), Myc-DDK-tagged |
CNY 14,060.00 |
|
| RC209192L4 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 18 (ADAMTS18), mGFP tagged |
CNY 14,060.00 |
|
| RG209192 | ADAMTS18 (tGFP-tagged) - Human ADAM metallopeptidase with thrombospondin type 1 motif, 18 (ADAMTS18) |
CNY 14,352.00 |
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