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TRPC6 (NM_004621) Human Untagged Clone
CAT＃: SC310040
TRPC6 (untagged)-Human transient receptor potential cation channel, subfamily C, member 6 (TRPC6)
CNY 10,240.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FSGS2; TRP6 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004621 edited
CCCGCTGGAACTGCCCACTCGGCTCCCCCGGGAGCGGGGCCCAGGCCAGTCGGGCGTTCC CGCCATGAGCCAGAGCCCGGCGTTCGGGCCCCGGAGGGGCAGTTCTCCCCGGGGCGCTGC CGGAGCCGCTGCGCGGCGCAACGAGAGCCAGGACTATCTGCTCATGGACTCGGAGCTGGG AGAAGACGGCTGCCCGCAAGCCCCGCTGCCTTGCTACGGCTACTACCCCTGCTTCCGGGG ATCTGACAACAGACTGGCTCACCGGCGGCAGACAGTTCTCCGTGAGAAGGGGAGAAGGTT AGCTAATCGAGGACCAGCATACATGTTTAGTGATCGCTCCACAAGCCTATCTATAGAGGA GGAACGCTTTTTGGATGCAGCTGAATATGGTAACATCCCAGTGGTGCGGAAGATGTTAGA AGAATGCCACTCACTCAACGTTAACTGTGTGGATTACATGGGCCAGAATGCCCTACAGTT GGCAGTGGCCAATGAGCATCTGGAAATTACAGAACTTCTTCTCAAGAAAGAAAACCTCTC TCGAGTTGGGGATGCTTTGCTTCTAGCTATTAGTAAAGGTTATGTTCGGATTGTGGAAGC AATTCTCAGTCATCCGGCTTTTGCTGAAGGCAAGAGGTTAGCAACCAGCCCTAGCCAGTC TGAACTCCAGCAAGATGATTTTTATGCCTATGATGAAGATGGGACACGGTTCTCCCATGA TGTGACTCCAATCATTCTGGCTGCCCACTGCCAGGAATATGAAATTGTGCATACCCTCCT GCGGAAGGGTGCTAGGATTGAACGGCCTCATGATTATTTCTGCAAGTGCAATGACTGCAA CCAGAAACAGAAGCATGACTCGTTTAGCCACTCCAGATCTAGGATTAATGCCTATAAAGG CCTGGCAAGTCCGGCTTACCTGTCATTGTCTAGTGAAGATCCAGTCATGACGGCTTTAGA ACTTAGCAATGAACTGGCAGTTCTGGCCAATATTGAGAAAGAGTTCAAGAATGACTACAA AAAACTGTCAATGCAGTGCAAAGACTTTGTTGTTGGACTCCTTGATCTGTGCAGAAACAC TGAAGAAGTCGAGGCCATTCTGAATGGGGATGTTGAAACGCTCCAGAGTGGTGATCACGG TCGCCCAAATCTCAGCCGTTTAAAACTTGCCATTAAATATGAAGTAAAAAAATTTGTAGC TCATCCAAACTGCCAACAGCAACTTCTCTCCATTTGGTATGAGAATCTTTCTGGTTTACG ACAGCAGACAATGGCGGTCAAGTTCCTTGTGGTCCTTGCTGTTGCCATTGGACTGCCCTT CCTGGCTCTCATTTACTGGTTTGCTCCATGCAGCAAGATGGGGAAGATAATGCGTGGACC ATTCATGAAGTTTGTAGCACACGCAGCCTCCTTCACCATTTTTCTGGGACTGCTAGTCAT GAATGCAGCTGACAGATTTGAAGGCACAAAACTCCTTCCTAATGAAACCAGCACAGATAA TGCAAAACAGCTGTTCAGGATGAAAACATCCTGCTTCTCATGGATGGAGATGCTCATTAT ATCCTGGGTAATAGGCATGATATGGGCTGAATGTAAAGAAATCTGGACTCAGGGCCCCAA GGAATATTTGTTTGAGTTGTGGAACATGCTTGATTTTGGTATGTTAGCAATTTTCGCAGC ATCATTCATTGCGAGATTCATGGCATTTTGGCATGCTTCCAAAGCCCAGAGCATCATTGA CGCAAACGATACTTTGAAGGACTTGACGAAAGTAACATTGGGAGACAATGTGAAATACTA CAATTTGGCCAGGATAAAGTGGGACCCCTCTGATCCTCAAATAATATCTGAAGGTCTTTA TGCAATTGCTGTAGTTTTAAGTTTCTCTAGGATAGCTTATATTTTACCAGCAAATGAAAG CTTTGGACCTCTGCAGATATCACTTGGAAGAACAGTCAAAGACATCTTCAAGTTCATGGT CATATTCATTATGGTGTTTGTGGCCTTTATGATTGGAATGTTCAATCTCTACTCCTACTA CATTGGTGCAAAACAAAATGAAGCCTTCACAACAGTTGAAGAGAGTTTTAAGACACTGTT CTGGGCTATATTTGGACTTTCTGAAGTGAAATCAGTGGTCATCAACTATAACCACAAATT CATTGAAAACATTGGTTACGTTCTTTATGGAGTCTATAATGTTACGATGGTCATTGTTTT GCTAAATATGTTAATTGCCATGATCAACAGTTCATTCCAGGAAATTGAGGATGACGCTGA TGTGGAGTGGAAATTTGCAAGGGCCAAACTCTGGTTTTCCTACTTTGAGGAGGGCAGAAC ACTTCCTGTACCCTTCAATCTGGTGCCGAGTCCAAAGTCCCTGTTTTATCTCTTACTGAA GCTTAAAAAATGGATTTCTGAGCTGTTCCAGGGCCATAAAAAAGGTTTCCAGGAAGATGC AGAGATGAACAAGATAAATGAAGAAAAGAAACTTGGAATTTTAGGAAGTCATGAAGACCT TTCAAAATTATCACTTGACAAAAAACAGGTTGGGCACAATAAACAACCAAGTATAAGGAG CTCAGAAGATTTCCATCTAAATAGTTTCAATAATCCTCCAAGACAATATCAGAAAATAAT GAAAAGGCTCATTAAAAGATATGTACTGCAGGCCCAGATAGATAAGGAGAGTGATGAAGT GAACGAAGGGGAACTGAAGGAAATTAAGCAGGACATCTCAAGTCTCCGCTATGAACTCCT TGAAGAAAAATCTCAGAATACAGAAGACCTAGCAGAACTTATTAGAGAACTTGGAGAGAA ATTATCCATGGAACCAAATCAAGAGGAAACCAATAGATAATGCGAAGACTTCCTTAGAAA TTCATATTTATTTGTCCACTTGAAGCCATATTATTTTCTGATTTATTTTCTTAAGTGCCA ATGGGCCCACCTTTTAAACAAGAAAACGTTAAATAACTTGGGCCATCCTATCATCTGGAG CCCTAGTATCTAATTTTTTTGGTGATTAAACTCCATTGTTCAGGGTAAAGGCTGTAGATA ATGAGGAAAATTATGCCCAGTTGTTTGGTGCTTGTTTTATAAACTGCTTTCTTGGATATA ACTAACTCTTGTGATGATGTCATTGCCATGTAGTGTCTGCCTGAAAATGGGTCCCAGCGG ACAGGGGCTGACCCACGTTACTCCCCATGCGGTTTTTCCTCTGAAGTTTATTTCAGGTTC CTTCTTGCCTGCTCTGTGGATCCCCTGCTGGGGACTCCCAGCTCTGAAATTTGGGAAAAA GTAGCCCATGGGCCTTTAGAATGCTTTAATCCTTTCTTTAGAATGCTGTTTAAACACCAT TTACCCTACTTATCCCTCAATGCACATGATTGATACCGTTCATACAAAATGGTCTTACAT CTATGTAAAATTTTCTGATTCATCTATTTGAAAACATTACACTTAACAATGAAAAAAGTT TTTCCTCCACTGAACCCTGGAAACATGGTCCAGTTTTGTGTGTGTGCGTGTGTGTAAATG TGTACACACAGACATAAAGTACTTGCCCTATTTAGTTTGTGGCTAATGTGGACACACAAA AGCTCTTTATGTTATAAATTTTTATTGTCACTAAAAAATTTTACTGTCTAAATAAGTACC TTTTATTGGAGAAAAATCAAAACCCCAAACAAACACTGTGGTTGTTTGGTTCCATTATAG CACAATTTTGTGCCATTTCTGGGAGCATTTACAGATGAATCCCCACACTTAGCCATTGAA TGTAAAGGGGAAAAATAAGGTGAGAATTTGTAAATACTTATCTGTTATTTTCAATATGTT CTATCCTTCTACCCAAATATATAAAACAGGAATTTGCATTCATGTGCATTTACCAAGAGG TTGTTGTTGTTACTTACTGATCATGTGAAGTGGTGTCTTAAACAACTAAAAGCGATGAAG GTTCATATGTTTACTCAAAGACCATTGGCATTCAGAGGATGCTGGACATTAACTGGAACT GCTACTTCCAATTCAATAATGGGAGATTTCAAATGCAAATCTTTAACTTCATCTTAAAGA TGAAATGGTTGCAGAAAATCTGTTTAGCTCCAACTTTGGCTTAATTTAAATCAAAGAACA TTTATGTAACCAGATCAGAAAATACAGCTGAAAATT >OriGene 5' read for NM_004621 unedited
TCGACAGCTGTATACGACTTACTATAGGGCGGCCGCGAATTCGCCCTTCCCGCCGGAACC GCCCACTCGGCTCCCCCGGGAGCGGGGCCCAGGCCAGTCGGGCGTTCCCGCCATGAGCCA GAGCCCGGCGTTCGGGCCCCGGAGGGGCAGTTCTCCCCGGGGCGCTGCCGGAGCCGCTGC GCGGCGCAACGAGAGCCAGGACTATCTGCTCATGGACTCGGAGCTGGGAGAAGACGGCTG CCCGCAAGCCCCGCTGCCTTGCTACGGCTACTACCCCTGCTTCCGGGGACCTGACAACAG ACTGGCTCACCGGCGGCAGACAGTTCTCCGTGAGAAGGGGAGAAGGTTAGCTAATCGAGG ACCAGCATACATGTTTAGTGATCGCTCCACAAGCCTATCTATAGAGGAGGAACGCTTTTT GGATGCAGCTGAATATGGTAACATCCCAGTGGTGCGGAAGATGTTAGAAGAATGCCACTC ACTCAACGTTAACTGTGTGGATTACATGGGCCAGAATGCCCTACAGTTGGCAGTGGCCAA TGAGCATCTGGAAATTACAGAACTTCTTCTCAAGAAAGAAAACCTCTCTCGAGTTGGGGA TGCTTTGCTTCTAGCTATTAGTAAAGGTTATGTTCGGATTGTGGAAGCAATTCTCAGTCA TCCGGCTTTTGCTGAAGGCAAGAGGTTAGCAACCAGCCCTAGCCAGTCTGAACTCCAGCA AGATGATTTTTATGCCTATGATGAAGATGGGACACGGTTCTCCCATGATGTGACTCCAAT CATTCTGGCTGCCCACTGCCAGGAATATGAAATTGTGCATACCCTCCTGCGGAAGGTGCT AGGATTGAACGGCCTCATGATTATTTCTGCAGTGCAATGACTGCACCAGAACAGAGCATG ACTCGTTTAGCCCCTCCAGATCTAGGATAATGCCTATAAGGCCTGGCAAGTCCGCTTACC TGTCATGT |
| Restriction Sites | Please inquire |
| ACCN | NM_004621 |
| Insert Size | 4200 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004621.3, NP_004612.2 |
| RefSeq Size | 4564 bp |
| RefSeq ORF | 2796 bp |
| Locus ID | 7225 |
| UniProt ID | Q9Y210 |
| Domains | ANK, ion_trans |
| Protein Families | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane |
| Gene Summary | The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells
,null,
Open Biology
,PubMed ID 22724068
[TRPC6]
|
|
Essential Role of TRPC6 Channels in G2/M Phase Transition and Development of Human Glioma
,Xia Ding, Zhuohao He, Kechun Zhou, Ju Cheng, Hailan Yao, Dongliang Lu, Rong Cai, Yening Jin, Bin Dong, Yinghui Xu, and Yizheng Wang,
J Natl Cancer Inst, Jul 2010; 102: 1052 - 1068
[TRPC6]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210783 | TRPC6 (Myc-DDK-tagged)-Human transient receptor potential cation channel, subfamily C, member 6 (TRPC6) |
CNY 10,224.00 |
|
| RC210783L1 | Lenti ORF clone of Human transient receptor potential cation channel, subfamily C, member 6 (TRPC6), Myc-DDK-tagged |
CNY 12,624.00 |
|
| RC210783L2 | Lenti ORF clone of Human transient receptor potential cation channel, subfamily C, member 6 (TRPC6), mGFP tagged |
CNY 5,890.00 |
|
| RC210783L3 | Lenti ORF clone of Human transient receptor potential cation channel, subfamily C, member 6 (TRPC6), Myc-DDK-tagged |
CNY 12,624.00 |
|
| RC210783L4 | Lenti ORF clone of Human transient receptor potential cation channel, subfamily C, member 6 (TRPC6), mGFP tagged |
CNY 12,624.00 |
|
| RG210783 | TRPC6 (tGFP-tagged) - Human transient receptor potential cation channel, subfamily C, member 6 (TRPC6) |
CNY 11,824.00 |
