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ABCD2 (NM_005164) Human Untagged Clone
CAT＃: SC310135
ABCD2 (untagged)-Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2)
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABC39; ALDL1; ALDR; ALDRP; hALDR |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC310135 representing NM_005164.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGACACATATGCTAAATGCAGCAGCTGATCGAGTGAAATGGACCAGATCGAGTGCTGCTAAGAGGGCT GCCTGCCTGGTGGCTGCGGCATATGCTCTGAAAACCCTCTATCCCATCATTGGCAAGCGTTTAAAGCAA TCTGGCCACGGGAAGAAAAAAGCAGCAGCTTACCCTGCTGCAGAGAACACAGAAATACTGCATTGCACC GAGACCATTTGTGAAAAACCTTCGCCTGGAGTGAATGCAGATTTCTTCAAACAGCTACTAGAACTTCGG AAAATTTTGTTTCCAAAACTTGTGACCACTGAAACAGGGTGGCTCTGCCTGCACTCAGTGGCTCTAATC TCAAGAACCTTTCTTTCTATCTATGTGGCTGGTCTGGATGGAAAAATCGTGAAAAGCATTGTGGAAAAG AAGCCTCGGACTTTCATCATCAAATTAATCAAGTGGCTTATGATTGCCATCCCTGCTACCTTCGTCAAC AGTGCAATAAGGTACCTGGAATGCAAATTGGCTTTGGCCTTCAGAACTCGCCTAGTAGACCACGCCTAT GAAACCTATTTTACAAATCAGACTTATTATAAAGTGATCAATATGGATGGGAGGCTGGCAAACCCTGAC CAATCTCTTACGGAGGATATTATGATGTTCTCCCAATCTGTGGCTCACTTGTATTCCAATCTGACCAAA CCTATTTTAGATGTAATGCTGACCTCCTATACACTCATTCAAACTGCTACATCCAGAGGAGCAAGCCCA ATTGGGCCCACCCTACTAGCAGGACTTGTGGTGTATGCCACTGCTAAAGTGTTAAAAGCCTGTTCTCCC AAATTTGGCAAACTGGTGGCAGAGGAAGCACATAGAAAAGGCTATTTGCGGTATGTGCACTCGAGAATT ATAGCCAATGTAGAAGAAATTGCCTTTTACAGAGGACATAAGGTAGAAATGAAACAACTTCAGAAAAGT TACAAAGCTTTAGCAGATCAGATGAACCTCATTTTATCCAAACGTTTGTGGTACATCATGATAGAACAG TTCCTGATGAAGTATGTTTGGAGCAGCAGTGGACTAATTATGGTGGCTATACCTATTATCACTGCAACT GGCTTTGCAGATGGTGAGGATGGCCAAAAGCAAGTTATGGTTAGTGAACGGACAGAAGCCTTTACCACT GCTCGAAATTTACTGGCCTCTGGAGCTGATGCTATTGAAAGGATTATGTCTTCATACAAAGAGGTCACT GAATTAGCAGGCTACACTGCTCGAGTGTACAATATGTTTTGGGTCTTTGATGAAGTAAAAAGAGGCATT TATAAGAGAACTGCTGTCATTCAAGAATCTGAAAGCCATAGCAAGAATGGAGCTAAGGTAGAATTACCT CTCAGTGACACATTGGCAATTAAAGGAAAAGTTATTGATGTGGATCACGGAATTATTTGTGAAAATGTT CCCATAATTACACCAGCAGGAGAAGTGGTGGCTTCCAGGCTAAACTTCAAAGTAGAAGAAGGAATGCAT CTTTTGATAACTGGTCCCAATGGTTGTGGGAAAAGTTCTCTCTTCAGAATTCTAAGTGGGCTCTGGCCT GTGTATGAAGGAGTCCTCTATAAACCACCTCCTCAACATATGTTTTATATTCCACAAAGGCCATATATG TCTCTTGGAAGTCTTCGGGATCAAGTCATTTACCCTGATTCAGTGGATGATATGCATGATAAAGGTTAT ACAGACCAAGATCTGGAACGTATCCTACACAATGTCCATCTCTATCACATAGTTCAAAGAGAAGGAGGA TGGGATGCTGTTATGGACTGGAAAGATGTCCTGTCAGGAGGGGAAAAGCAAAGAATGGGCATGGCTCGT ATGTTTTATCATAAACCAAAATATGCCTTGCTGGATGAATGTACCAGTGCTGTCAGCATTGATGTCGAA GGAAAGATATTTCAGGCTGCAAAAGGGGCTGGAATTTCCTTACTGTCTATAACACACAGACCTTCTCTT TGGAAATACCACACACATTTATTACAGTTTGATGGTGAAGGAGGTTGGCGCTTTGAACAATTGGATACT GCTATCCGTTTGACATTGAGTGAAGAAAAACAAAAGCTAGAATCTCAGCTAGCTGGAATTCCCAAAATG CAGCAGAGACTCAATGAACTATGTAAAATTTTGGGAGAAGACTCAGTGCTGAAAACAATTAAAAATGAA GATGAGACATCTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_005164 |
| Insert Size | 2223 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005164.3 |
| RefSeq Size | 5341 bp |
| RefSeq ORF | 2223 bp |
| Locus ID | 225 |
| UniProt ID | Q9UBJ2 |
| Domains | ABC_tran, AAA |
| Protein Families | Druggable Genome |
| Protein Pathways | ABC transporters |
| MW | 83.2 kDa |
| Gene Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211199 | ABCD2 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2) |
CNY 5,424.00 |
|
| RC211199L1 | Lenti ORF clone of Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), Myc-DDK-tagged |
CNY 7,824.00 |
|
| RC211199L2 | Lenti ORF clone of Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), mGFP tagged |
CNY 7,700.00 |
|
| RC211199L3 | Lenti ORF clone of Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), Myc-DDK-tagged |
CNY 7,824.00 |
|
| RC211199L4 | Lenti ORF clone of Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), mGFP tagged |
CNY 7,824.00 |
|
| RG211199 | ABCD2 (tGFP-tagged) - Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2) |
CNY 7,024.00 |
