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TBC1D23 (NM_018309) Human Untagged Clone
CAT＃: SC310172
TBC1D23 (untagged)-Human TBC1 domain family, member 23 (TBC1D23), transcript variant 2
CNY 13,210.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NS4ATP1; PCH11 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC310172 representing NM_018309.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGGAAGGAGAAGATGTGCCGCCGCTGCCAACGTCGAGCGGCGACGGCTGGGAAAAAGATCTTGAA GAAGCTCTGGAAGCAGGAGGTTGTGATCTTGAAACGTTGAGAAATATAATTCAAGGAAGACCGCTGCCT GCTGATCTGAGGGCCAAAGTTTGGAAGATTGCTCTGAATGTTGCAGGAAAAGGTGATAGTTTGGCATCA TGGGATGGTATTTTAGACTTGCCAGAACAGAACACTATTCACAAAGATTGCCTGCAGTTTATTGACCAG CTTTCAGTGCCAGAGGAGAAGGCAGCAGAATTACTTTTGGATATTGAATCTGTAATTACCTTTTATTGT AAATCACGTAACATTAAATATAGCACATCCCTTAGCTGGATACATCTACTGAAACCATTGGTGCATCTT CAACTGCCACGCAGCGATTTATACAACTGCTTTTATGCCATAATGAATAAGTACATTCCCAGGGATTGT TCCCAGAAAGGGAGACCATTTCATCTCTTCAGGTTGCTCATCCAATACCATGAGCCTGAGCTTTGTTCT TATCTTGATACAAAGAAAATTACTCCAGACTCCTATGCACTCAACTGGCTTGGAAGTCTTTTTGCATGT TACTGTTCCACTGAAGTCACTCAGGCAATATGGGATGGATATCTACAACAAGCAGATCCATTTTTTATT TATTTCTTAATGTTAATTATCCTTGTTAATGCAAAAGAAGTTATTTTAACACAAGAGTCAGACAGCAAA GAAGAAGTTATCAAGTTCTTGGAAAATACTCCATCCAGTCTGAATATAGAAGATATAGAAGACCTTTTC TCTCTGGCTCAGTATTATTGCAGCAAAACACCGGCTTCTTTTAGGAAGGATAATCACCATCTCTTTGGT AGTACTTTGTTGGGAATTAAGGATGATGATGCAGATCTGAGTCAGGCTCTTTGTCTGGCCATCTCCGTG TCAGAGATCCTTCAAGCGAATCAGCTACAAGGGGAAGGAGTCCGGTTCTTTGTGGTGGATTGCCGTCCT GCAGAACAATATAATGCTGGGCATTTATCAACTGCTTTCCACTTAGATTCAGACCTGATGCTTCAGAAT CCATCTGAGTTTGCACAGTCAGTAAAATCCTTGCTGGAAGCACAGAAGCAGTCCATTGAGTCTGGCTCC ATAGCTGGTGGGGAGCACCTCTGTTTTATGGGCAGTGGCAGGGAGGAAGAAGACATGTATATGAACATG GTCCTGGCACACTTTTTACAGAAAAACAAAGAATATGTGAGTATTGCCAGTGGAGGATTTATGGCACTG CAGCAGCACCTGGCAGACATTAATGTGGATGGACCAGAAAATGGATATGGCCATTGGATTGCTAGTACC TCAGGCTCAAGGAGCAGTATCAATTCTGTTGATGGTGAATCTCCTAATGGCTCAAGTGATAGAGGAATG AAATCACTAGTAAATAAAATGACTGTGGCTTTGAAGACAAAATCCGTTAATGTCAGGGAAAAAGTTATC AGTTTTATAGAGAATACATCAACTCCTGTGGATCGGCATGTGAGCAGCAGTGACAGAGTGGGCAAGCCT TACCGTGGCGTAAAGCCTGTTTTCAGCATTGGGGATGAAGAAGAATACGACACAGATGAAATTGACAGT TCTTCAATGTCAGATGATGATAGAAAAGAGGTTGTAAACATTCAGACTTGGATAAACAAACCAGATGTC AAACATCATTTTCCTTGTAAAGAAGTAAAAGAAAGTGGACACATGTTTCCCAGTCATCTGTTGGTTACT GCAACACATATGTACTGTTTAAGGGAGATTGTTTCACGGAAAGGATTGGCTTATATACAGTCTCGACAA GCGCTGAATTCTGTAGTTAAAATTACATCCAAAAAAAAACATCCTGAACTCATTACCTTCAAGTATGGA AATAGCAGTGCTTCAGGAATAGAAATCTTGGCAATCGAAAGGTATTTGATTCCAAATGCAGGGGATGCA ACTAAAGCCATAAAACAGCAGATCATGAAAGTTTTGGATGCTTTGGAAAGTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_018309 |
| Insert Size | 2055 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_018309.4 |
| RefSeq Size | 3841 bp |
| RefSeq ORF | 2055 bp |
| Locus ID | 55773 |
| UniProt ID | Q9NUY8 |
| Domains | TBC |
| Protein Families | Druggable Genome |
| MW | 76.5 kDa |
| Gene Summary | Putative Rab GTPase-activating protein which plays a role in vesicular trafficking (PubMed:28823707). Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (PubMed:29084197, PubMed:29426865). Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1 (PubMed:29426865). Plays a role in brain development, including in cortical neuron positioning (By similarity). May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity). May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an exon in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220480 | TBC1D23 (Myc-DDK-tagged)-Human TBC1 domain family, member 23 (TBC1D23), transcript variant 2 |
CNY 5,008.00 |
|
| RC220480L3 | Lenti ORF clone of Human TBC1 domain family, member 23 (TBC1D23), transcript variant 2, Myc-DDK-tagged |
CNY 9,120.00 |
|
| RC220480L4 | Lenti ORF clone of Human TBC1 domain family, member 23 (TBC1D23), transcript variant 2, mGFP tagged |
CNY 9,120.00 |
|
| RG220480 | TBC1D23 (tGFP-tagged) - Human TBC1 domain family, member 23 (TBC1D23), transcript variant 2 |
CNY 7,980.00 |
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