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ARTS1 (ERAP1) (NM_001040458) Human Untagged Clone
CAT＃: SC311137
ERAP1 (untagged)-Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2
CNY 6,896.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001040458 edited
GGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGGCTGGGCCTCAGGTGAGACTGCAG CTCCAGTCATCATCTTGATTGCAGCCCACAGAAACTACCAACCCACAGAAACTGTAGGTA GAGCAAGAAGATGGTGTTTCTGCCCCTCAAATGGTCCCTTGCAACCATGTCATTTCTACT TTCCTCACTGTTGGCTCTCTTAACTGTGTCCACTCCTTCATGGTGTCAGAGCACTGAAGC ATCTCCAAAACGTAGTGATGGGACACCATTTCCTTGGAATAAAATACGACTTCCTGAGTA CGTCATCCCAGTTCATTATGATCTCTTGATCCATGCAAACCTTACCACGCTGACCTTCTG GGGAACCACGAAAGTAGAAATCACAGCCAGTCAGCCCACCAGCACCATCATCCTGCATAG TCACCACCTGCAGATATCTAGGGCCACCCTCAGGAAGGGAGCTGGAGAGAGGCTATCGGA AGAACCCCTGCAGGTCCTGGAACACCCCCGTCAGGAGCAAATTGCACTGCTGGCTCCCGA GCCCCTCCTTGTCGGGCTCCCGTACACAGTTGTCATTCACTATGCTGGCAATCTTTCGGA GACTTTCCACGGATTTTACAAAAGCACCTACAGAACCAAGGAAGGGGAACTGAGGATACT AGCATCAACACAATTTGAACCCACTGCAGCTAGAATGGCCTTTCCCTGCTTTGATGAACC TGCCTTCAAAGCAAGTTTCTCAATCAAAATTAGAAGAGAGCCAAGGCACCTAGCCATCTC CAATATGCCATTGGTGAAATCTGTGACTGTTGCTGAAGGACTCATAGAAGACCATTTTGA TGTCACTGTGAAGATGAGCACCTATCTGGTGGCCTTCATCATTTCAGATTTTGAGTCTGT CAGCAAGATAACCAAGAGTGGAGTCAAGGTTTCTGTTTATGCTGTGCCAGACAAGATAAA TCAAGCAGATTATGCACTGGATGCTGCGGTGACTCTTCTAGAATTTTATGAGGATTATTT CAGCATACCGTATCCCCTACCCAAACAAGATCTTGCTGCTATTCCCGACTTTCAGTCTGG TGCTATGGAAAACTGGGGACTGACAACATATAGAGAATCTGCTCTGTTGTTTGATGCAGA AAAGTCTTCTGCATCAAGTAAGCTTGGCATCACAATGACTGTGGCCCATGAACTGGCTCA CCAGTGGTTTGGGAACCTGGTCACTATGGAATGGTGGAATGATCTTTGGCTAAATGAAGG ATTTGCCAAATTTATGGAGTTTGTGTCTGTCAGTGTGACCCATCCTGAACTGAAAGTTGG AGATTATTTCTTTGGCAAATGTTTTGACGCAATGGAGGTAGATGCTTTAAATTCCTCACA CCCTGTGTCTACACCTGTGGAAAATCCTGCTCAGATCCGGGAGATGTTTGATGATGTTTC TTATGATAAGGGAGCTTGTATTCTGAATATGCTAAGGGAGTATCTTAGTGCTGACGCATT TAAAAGTGGTATTGTACAGTATCTCCAGAAGCATAGCTATAAAAATACAAAAAACGAGGA CCTGTGGGATAGTATGGCAAGTATTTGCCCTACAGATGGTGTAAAAGGGATGGATGGCTT TTGCTCTAGAAGTCAACATTCATCTTCATCCTCACATTGGCATCAGGAAGGGGTGGATGT GAAAACCATGATGAACACTTGGACACTGCAGAAGGGTTTTCCCCTAATAACCATCACAGT GAGGGGGAGGAATGTACACATGAAGCAAGAGCACTACATGAAGGGCTCTGACGGCGCCCC GGACACTGGGTACCTGTGGCATGTTCCATTGACATTCATCACCAGCAAATCCGACATGGT CCATCGATTTTTGCTAAAAACAAAAACAGATGTGCTCATCCTCCCAGAAGAGGTGGAATG GATCAAATTTAATGTGGGCATGAATGGCTATTACATTGTGCATTACGAGGATGATGGATG GGACTCTTTGACTGGCCTTTTAAAAGGAACACACACAGCAGTCAGCAGTAATGATCGGGC GAGTCTCATTAACAATGCATTTCAGCTCGTCAGCATTGGGAAGCTGTCCATTGAAAAGGC CTTGGATTTATCCCTGTACTTGAAACATGAAACTGAAATTATGCCCGTGTTTCAAGGTTT GAATGAGCTGATTCCTATGTATAAGTTAATGGAGAAAAGAGATATGAATGAAGTGGAAAC TCAATTCAAGGCCTTCCTCATCAGGCTGCTAAGGGACCTCATTGATAAGCAGACATGGAC AGACGAGGGCTCAGTCTCAGAGCGAATGCTGCGGAGTCAACTACTACTCCTCGCCTGTGT GCACAACTATCAGCCGTGCGTACAGAGGGCAGAAGGCTATTTCAGAAAGTGGAAGGAATC CAATGGAAACTTGAGCCTGCCTGTCGACGTGACCTTGGCAGTGTTTGCTGTGGGGGCCCA GAGCACAGAAGGCTGGGATTTTCTTTATAGTAAATATCAGTTTTCTTTGTCCAGTACTGA GAAAAGCCAAATTGAATTTGCCCTCTGCAGAACCCAAAATAAGGAAAAGCTTCAATGGCT ACTAGATGAAAGCTTTAAGGGAGATAAAATAAAAACTCAGGAGTTTCCACAAATTCTTAC ACTCATTGGCAGGAACCCAGTAGGATACCCACTGGCCTGGCAATTTCTGAGGAAAAACTG GAACAAACTTGTACAAAAGTTTGAACTTGGCTCATCTTCCATAGCCCACATGGTAATGGG TACAACAAATCAATTCTCCACAAGAACACGGCTTGAAGAGGTAAAAGGATTCTTCAGCTC TTTGAAAGAAAATGGTTCTCAGCTCCGTTGTGTCCAACAGACAATTGAAACCATTGAAGA AAACATCGGTTGGATGGATAAGAATTTTGATAAAATCAGAGTGTGGCTGCAAAGTGAAAA GCTTGAACGTATGTAAAAATTCCTCCCTTGCCAGGTTCCTGTTATCTCTAATCACCAACA TTTTGTTGAGTGTATTTTCAAACTAGAGATGGCTGTTTTGGCTCCAACTGGAGATACTTT TTTCCCTTCAACTCATTTTTTGACTATCCCTGTGAAAAGAATAGCTGTTAGTTTTTCATG AATGGGCTATCGCTACCATGTGTTTTGTTCATCACAGGTGTTGCCCTGCAACGTAAACCC AAGTGTTGGGTTCCCTGCCACAGAAGAATAAAGTACCTTATTCTTCTCATTTTATAGTTT ATGCTTAAGCACCCGTGTCCAAAACCCTGTACCCCATGTTTATCATTCATAAACTGTTTC ATCAGCCAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001040458 |
| Insert Size | 3300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001040458.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001040458.1, NP_001035548.1 |
| RefSeq Size | 5085 bp |
| RefSeq ORF | 2826 bp |
| Locus ID | 51752 |
| UniProt ID | Q9NZ08 |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Gene Summary | The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010] Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
,Bufalieri, F;Infante, P;Bernardi, F;Caimano, M;Romania, P;Moretti, M;Lospinoso Severini, L;Talbot, J;Melaiu, O;Tanori, M;Di Magno, L;Bellavia, D;Capalbo, C;Puget, S;De Smaele, E;Canettieri, G;Guardavaccaro, D;Busino, L;Peschiaroli, A;Pazzaglia, S;Giannini, G;Melino, G;Locatelli, F;Gulino, A;Ayrault, O;Fruci, D;Di Marcotullio, L;,
Nat Commun
,PubMed ID 31341163
[ERAP1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205249 | ERAP1 (Myc-DDK-tagged)-Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2 |
CNY 6,896.00 |
|
| RC205249L1 | Lenti ORF clone of Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205249L2 | Lenti ORF clone of Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2, mGFP tagged |
CNY 9,296.00 |
|
| RC205249L3 | Lenti ORF clone of Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205249L4 | Lenti ORF clone of Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG205249 | ERAP1 (tGFP-tagged) - Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2 |
CNY 8,496.00 |
