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TGF alpha (TGFA) (NM_003236) Human Untagged Clone
CAT＃: SC311226
TGFA (untagged)-Human transforming growth factor, alpha (TGFA), transcript variant 1
CNY 1,200.00
CNY 3,990.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | TFGA |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003236 edited
GCCATTACGGCCGGGGACTCGGGCACCGCAGGTAGGGCAGGAGGCTGGAGAGCCTGCTGC CCGCCCGCCCGTAAAATGGTCCCCTCGGCTGGACAGCTCGCCCTGTTCGCTCTGGGTATT GTGTTGGCTGCGTGCCAGGCCTTGGAGAACAGCACGTCCCCGCTGAGTGCAGACCCGCCC GTGGCTGCAGCAGTGGTGTCCCATTTTAATGACTGCCCAGATTCCCACACTCAGTTCTGC TTCCATGGAACCTGCAGGTTTTTGGTGCAGGAGGACAAGCCAGCATGTGTCTGCCATTCT GGGTACGTTGGTGCACGCTGTGAGCATGCGGACCTCCTGGCCGTGGTGGCTGCCAGCCAG AAGAAGCAGGCCATCACCGCCTTGGTGGTGGTCTCCATCGTGGCCCTGGCTGTCCTTATC ATCACATGTGTGCTGATACACTGCTGCCAGGTCCGAAAACACTGTGAGTGGTGCCGGGCC CTCATCTGCCGGCACGAGAAGCCCAGCGCCCTCCTGAAGGGAAGAACCGCTTGCTGCCAC TCAGAAACAGTGGTCTGAAGAGCCCAGAGGAGGAGTTTGGCCAGGTGGACTGTGGCAGAT CAATAAAGAAAGGCTTCTTCAGGACAGCACTGCCAGAGATGCCTGGGTGTGCCACAGACC TTCCTACTTGGCCTGTAATCACCTGTGCAGCCTTTTGTGGGCCTTCAAAACTCTGTCAAG AACTCCGTCTGCTTGGGGTTATTCAGTGTGACCTAGAGAAGAAATCAGCGGACCACGATT TCAAGACTTGTTAAAAAAGAACTGCAAAGAGACGGACTCCTGTTCACCTAGGTGAGGTGT GTGCAGCAGTTGGTGTCTGAGTCCACATGTGTGCAGTTGTCTTCTGCCAGCCATGGATTC CAGGCTATATATTTCTTTTTAATGGGCCACCTCCCCACAACAGAATTCTGCCCAACACAG GAGATTTCTATAGTTATTGTTTTCTGTCATTTGCCTACTGGGGAAGAAAGTGAAGGAGGG GAAACTGTTTAATATCACATGAAGACCCTAGCTTTAAGAGAAGCTGTATCCTCTAACCAC GAGACCCTCAACCAGCCCAACATCTTCCATGGACACATGACATTGAAGACCATCCCAAGC TATCGCCACCCTTGGAGATGATGTCTTATTTATTAGATGGATAATGGTTTTATTTTTAAT CTCTTAAGTCAATGTAAAAAGTATAAAACCCCTTCAGACTTCTAAAAAAAAAAAAAAAAA AAAAAAAAAAAAA >OriGene 5' read for NM_003236 unedited
NTTTTGTTNGCGTTCATCATTTGTNATACGACTCACTATAGGCGGCCGCGAATTCGCCAT TACGGCCGGGGACTCGGGCACCGCAGGTAGGGCAGGAGGCTGGAGAGCCTGCTGCCCGCC CGCCCGTAAAATGGTCCCCTCGGCTGGACAGCTCGCCCTGTTCGCTCTGGGTATTGTGTT GGCTGCGTGCCAGGCCTTGGAGAACAGCACGTCCCCGCTGAGTGCAGACCCGCCCGTGGC TGCAGCAGTGGTGTCCCATTTTAATGACTGCCCAGATTCCCACACTCAGTTCTGCTTCCA TGGAACCTGCAGGTTTTTGGTGCAGGAGGACAAGCCAGCATGTGTCTGCCATTCTGGGTA CGTTGGTGCACGCTGTGAGCATGCGGACCTCCTGGCCGTGGTGGCTGCCAGCCAGAAGAA GCAGGCCATCACCGCCTTGGTGGTGGTCTCCATCGTGGCCCTGGCTGTCCTTATCATCAC ATGTGTGCTGATACACTGCTGCCAGGTCCGAAAACACTGTGAGTGGTGCCGGGCCCTCAT CTGCCGGCACGAGAAGCCCAGCGCCCTCCTGAAGGGAAGAACCGCTTGCTGCCACTCAGA AACAGTGGTCTGAAGAGCCCAGAGGAGGAGTTTGGCCAGGTGGACTGTGGCAGATCAATA AAGAAAGGCTTCTTCAGGACAGCACTGCCAGAGATGCCTGGGTGTGCCACAGACCTTCCT ACTTGGCCTGTAATCACCTGTGCAGCCTTTTGTGGGCCTTCAAAACTCTGTCAAGAACTC CGTCTGCTTGGGGTTATTCAGTGTGACCTAGAGAAGAATCAGCGGACCACGATTTCAAGA CTTGTTAAAAAAGAACTGCANAGAGAC |
| Restriction Sites | Please inquire |
| ACCN | NM_003236 |
| Insert Size | 1300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003236.1, NP_003227.1 |
| RefSeq Size | 4119 bp |
| RefSeq ORF | 483 bp |
| Locus ID | 7039 |
| UniProt ID | P01135 |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | ErbB signaling pathway, Glioma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Renal cell carcinoma |
| Gene Summary | This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Transcript Variant: This variant (1) encodes isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Autocrine EGF and TGF ‐α promote primary and acquired resistance to ALK / c‐Met kinase inhibitors in non‐small‐cell lung cancer
,null,
Pharmacology Research & Perspectives
,PubMed ID 36583451
[TGFA]
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| RC202741L2 | Lenti ORF clone of Human transforming growth factor, alpha (TGFA), transcript variant 1, mGFP tagged |
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| RC202741L3 | Lenti ORF clone of Human transforming growth factor, alpha (TGFA), transcript variant 1, Myc-DDK-tagged |
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| RC202741L4 | Lenti ORF clone of Human transforming growth factor, alpha (TGFA), transcript variant 1, mGFP tagged |
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| RG202741 | TGFA (tGFP-tagged) - Human transforming growth factor, alpha (TGFA), transcript variant 1 |
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