LTBP4 (NM_001042544) Human Untagged Clone
CAT#: SC311430
LTBP4 (untagged)-Human latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 1
CNY 11,120.00
Cited in 2 publications. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ARCL1C; LTBP-4; LTBP4L; LTBP4S |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_001042544 edited
ATGCCGAGGCCTGGCACCAGCGGCCGCCGCCCCCTCCTGCTGGTGCTGTTGCTGCCGCTC TTCGCAGCCGCCACCTCCGCCGCCAGCCCCAGCCCCAGCCCCAGCCAGGTCGTCGAGGTC CCGGGGGTCCCCAGCCGCCCGGCCAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACG TCTAGGAGGAGCCGCTGCATCCGAGCCTTCTGCAGGGTCCGAAGCTGCCAGCCCAAAAAG TGTGCAGGCCCCCAGCGGTGCCTGAACCCAGTGCCTGCAGTGCCCAGTCCCAGCCCCAGC GTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAGGCCAGAGCT CTACTGAAGCGGCGGCGGCCCCGGGGGCCAGGGGGCCGGGGACTACTGAGAAGGAGGCCC CCACAGCGTGCCCCCGCTGGCAAGGCCCCGGTCCTGTGTCCCTTGATCTGTCACAATGGC GGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGC CAGTTGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCC GTGTACACTATGCCACTGGCCAACCACCGCGACGACGAGCACGGCGTGGCATCTATGGTG AGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTG TCTGGCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGG GCGGAGGCGGCAGCGCCCTACACGGTGTTGGCACAGAGCGCGCCGCGGGAGGACGGCTAC TCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCC CCGCTGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGC GTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGGGGAACTCCGAAAGAGTGAGCGCCCCA GATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAG TGCGCGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACG TGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGTCCCGCAGCAGCTGCATCTCCCAACAC GTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTG CCCATTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGG GGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCTCAGAGGGTTTCCGGGAGATCTGCCCG GCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGC CAGGAGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCA TCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGCCCCGGCCTGAACCCCGGCCCGATCCC CGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCT GAATCAGGTCCCTCCTCCGGCATGTGTCAGCGCAACCCCCAGGTCTGCGGCCCAGGACGC TGCATTTCCCGGCCCAGCGGCTACACCTGCGCTTGCGACTCTGGCTTCCGGCTCAGCCCC CAGGGCACCCGATGCATTGATGTGGACGAATGTCGCCGCGTGCCCCCGCCCTGTGCTCCC GGGCGCTGCGAGAACTCACCAGGCAGCTTCCGCTGCGTGTGCGGCCCGGGCTTCCGAGCC GGCCCACGGGCTGCGGAATGCCTGGATGTGGACGAGTGCCACCGCGTGCCGCCGCCGTGT GACCTCGGGCGCTGCGAGAACACGCCAGGCAGCTTCCTGTGCGTGTGCCCCGCCGGGTAC CAGGCTGCACCGCACGGAGCCAGCTGCCAGGATGTGGATGAATGCACCCAGAGCCCAGGC CTGTGTGGCCGAGGGGCCTGCAAGAACCTGCCTGGCTCTTTCCGCTGTGTTTGCCCGGCT GGCTTCCGGGGCTCGGCGTGTGAAGAGGATGTGGATGAGTGTGCCCAGGAGCCGCCGCCC TGTGGGCCCGGCCGCTGTGACAACACGGCAGGCTCCTTTCACTGTGCCTGCCCTGCTGGC TTCCGCTCCCGAGGGCCCGGGGCCCCCTGCCAAGATGTGGATGAGTGTGCCCGAAGCCCC CCACCCTGCACCTACGGCCGGTGTGAGAACACAGAAGGCAGCTTCCAGTGTGTCTGCCCC ATGGGCTTCCAACCCAACACTGCTGGCTCCGAGTGCGAGGATGTGGATGAGTGTGAGAAC CACCTCGCATGCCCTGGGCAGGAGTGTGTGAACTCGCCCGGCTCCTTCCAGTGCAGGACC TGTCCTTCTGGCCACCACCTGCACCGTGGCAGATGCACTGATGTGGACGAATGCAGTTCG GGTGCCCCTCCCTGTGGTCCCCACGGCCACTGCACTAACACCGAAGGCTCCTTCCGCTGC AGCTGCGCGCCAGGCTACCGGGCGCCGTCGGGTCGGCCCGGGCCCTGCGCAGACGTGAAC GAGTGCCTGGAGGGCGATTTCTGCTTCCCTCACGGCGAGTGCCTCAACACTGACGGCTCC TTTGCCTGTACTTGTGCCCCTGGCTACCGACCCGGACCCCGCGGAGCCTCTTGCCTCGAC GTTGACGAGTGCAGCGAGGAGGACCTTTGCCAGAGCGGCATCTGTACCAACACCGACGGC TCCTTCGAGTGCATCTGTCCTCCGGGACACCGCGCTGGCCCGGACCTCGCCTCCTGCCTC GACGTGGACGAATGTCGCGAGCGAGGCCCAGCCCTGTGCGGGTCGCAGCGCTGTGAGAAC TCTCCCGGCTCCTACCGCTGTGTCCGGGACTGCGATCCTGGGTACCACGCGGGCCCCGAG GGCACCTGTGACGATGTGGATGAGTGCCAAGAATATGGTCCCGAGATTTGTGGAGCCCAG CGTTGTGAGAACACCCCTGGCTCCTACCGCTGCACACCAGCCTGTGACCCTGGCTATCAG CCCACGCCAGGGGGCGGATGCCAGGATGTGGACGAATGCCGGAACCGGTCCTTCTGCGGT GCCCACGCCGTGTGCCAGAACCTGCCCGGCTCCTTCCAGTGCCTCTGTGACCAGGGTTAC GAGGGGGCACGGGATGGGCGTCACTGCGTGGATGTGAACGAGTGTGAAACACTACAGGGT GTATGTGGAGCTGCCCTGTGTGAAAATGTCGAAGGCTCCTTCCTCTGTGTCTGCCCCAAC AGCCCGGAAGAGTTTGACCCCATGACTGGACGCTGTGTTCCCCCACGAACTTCTGCTGGC ACGTTCCCAGGCTCGCAGCCCCAGGCACCTGCTAGCCCCGTTCTGCCCGCCAGGCCACCT CCGCCACCCCTGCCCCGCCGACCCAGCACACCTAGGCAGGGCCCTGTGGGGAGTGGGCGC CGGGAGTGCTACTTTGACACAGCGGCCCCGGATGCATGTGACAACATCCTGGCTCGGAAT GTGACATGGCAGGAGTGCTGCTGTACTGTGGGTGAGGGCTGGGGCAGCGGCTGCCGCATC CAGCAGTGCCCGGGCACCGAGACAGCTGAGTACCAGTCATTGTGCCCTCACGGCCGGGGC TACCTGGCGCCCAGTGGAGACCTGAGCCTCCGGAGAGACGTGGACGAATGTCAGCTCTTC CGAGACCAGGTGTGCAAGAGTGGCGTGTGTGTGAACACGGCCCCGGGCTACTCATGCTAT TGCAGCAACGGCTACTACTACCACACACAGCGGCTGGAGTGCATCGACAATGACGAGTGC GCCGATGAGGAACCGGCCTGTGAGGGCGGCCGCTGTGTCAACACTGTGGGCTCTTATCAC TGTACCTGCGAGCCCCCACTGGTGCTGGATGGCTCGCAGCGCCGCTGCGTCTCCAACGAG AGCCAGAGCCTCGATGACAATCTGGGAGTGTGCTGGCAGGAAGTGGGGGCTGACCTCGTG TGCAGCCACCCTCGGCTGGACCGTCAGGCCACCTACACAGAGTGCTGCTGCCTGTATGGA GAGGCCTGGGGCATGGACTGCGCCCTCTGCCCTGCGCAGGACTCAGATGACTTCGAGGCC CTGTGCAATGTGCTACGCCCCCCCGCATATAGCCCCCCGCGACCAGGTGGCTTTGGACTC CCCTACGAGTACGGCCCAGACTTAGGTCCACCTTACCAGGGCCTCCCATATGGGCCTGAG TTGTACCCACCACCTGCGCTACCCTACGACCCCTACCCACCGCCACCTGGGCCCTTCGCC CGCCGGGAGGCTCCTTATGGGGCACCCCGCTTCGACATGCCAGACTTTGAGGACGATGGT GGCCCCTATGGCGAATCTGAGGCTCCTGCGCCACCTGGCCCGGGCACCCGCTGGCCCTAT CGGTCCCGGGACACCCGCCGCTCCTTCCCAGAGCCCGAGGAGCCTCCTGAAGGTGGAAGC TATGCTGGTTCCCTGGCTGAGCCCTACGAGGAGCTGGAGGCGGAGGAGTGCGGGATCCTG GACGGCTGCACCAACGGCCGCTGCGTGCGCGTCCCCGAAGGCTTCACCTGCCGTTGCTTC GACGGCTACCGCCTGGACATGACCCGCATGGCCTGCGTTGACATCAACGAGTGTGATGAG GCCGAGGCTGCCTCCCCGCTGTGCGTCAACGCGCGTTGCCTCAACACGGATGGCTCCTTC CGCTGCATCTGCCGCCCGGGATTCGCACCCACGCACCAGCCGCACCACTGTGCGCCCGCA CGGCCCCGGGCCTGA |
Restriction Sites | Please inquire |
ACCN | NM_001042544 |
Insert Size | 5000 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001042544.1, NP_001036009.1 |
RefSeq Size | 5163 bp |
RefSeq ORF | 4875 bp |
Locus ID | 8425 |
UniProt ID | Q8N2S1 |
Protein Families | Druggable Genome |
Gene Summary | The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ
,null,
PLoS Genetics
,PubMed ID 27148972
[LTBP4]
|
Genotype-Specific Interaction of Latent TGFß Binding Protein 4 with TGFß
,Lamar, KM;Miller, T;Dellefave-Castillo, L;McNally, EM;,
PLoS ONE
,PubMed ID 26918958
[LTBP4]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC224230 | LTBP4 (Myc-DDK-tagged)-Human latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 1 |
CNY 11,112.00 |
|
RC224230L3 | Lenti-ORF clone of LTBP4 (Myc-DDK-tagged)-Human latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 1 |
CNY 13,512.00 |
|
RC224230L4 | Lenti-ORF clone of LTBP4 (mGFP-tagged)-Human latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 1 |
CNY 18,150.00 |
|
RG224230 | LTBP4 (tGFP-tagged) - Human latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 1 |
CNY 17,860.00 |