SOD2 (BC016934) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	indophenoloxidase B; IPO-B; manganese-containing superoxide dismutase; manganese superoxide dismutase; mangano-superoxide dismutase; Mn-SOD; MNSOD; Mn superoxide dismutase; OTTHUMP00000017530; OTTHUMP00000017531; superoxide dismutase 2, mitochondrial
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC016934 edited GTGGTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGCGGTAGCACCAGCACTAG CAGCATGTTGAGCCGGGCAGTGTGCGGCACCAGCAGGCAGCTGGCTCCGGCTTTGGGGTA TCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCGCCCTGGA ACCTCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGT GAACAACCTGAACGTCACCGAGGAGAAGTACCAGGAGGCGTTGGCCAAGGGTAGGTTCCA GGCTGAGCGGCGGGAGGCAGTCCCCGGCAGAGGCGACCCCAGGGAGCCAGGCCCCATACG GACGGGCCTCTCCGTGGAGGAGAACTCGCTTCGTATTTGTACCGGTTCCGAGTTTTCCAG GCACGATAGTCTCTCTTTTAAACACATGGTCTACCTCATTGTAGAAGGAGTGCCTCGATG GGTTTGAACACACTTCTGTCATCTCAGGGAACTTGGGGTCCTGCGAAGGAGCTTGCCTTA CTGTTGTGAGCCACATTCCGTTACACATATTGCCAGCACTGGTGAATTGTAGGGCCTGAA AAGAAAGCTCTACTGTGTCACTCGTTTTTTTTGCAAATTGAAATTGTTCTTGTTGTATAA TATGCTTTGGGGAAATGTTTGGTCTCTCAGGTAGGTGTGCCAGCCGTTTGCAGGAGGGCT GAGAGCGCCTGTCCACTGGTGGCCAGACATCATCGGGTCCGCAGGTGTCTCTGAGTGTCA GGGTCACCTCCTGATAGAAGTGGGAGTGGTGTCTTACTGCCAGGTCACACTGAAGGTGGG AGACAGGAGGACACTACTCCGTGCTAGGAACCATGGTCCTTGTCATCTTCCTGAGAGCAA ACGGGGTCGGGACTCCAGCCTAGGACTTGGAGACTCCCTGCATCCCCAGCTACCCTGCAG GTGAAACTTCACTGAGCCCACTTGACTTCAGGTGGGAGAGGAGGAGGCACACCGTTGTGG TGTGCGTTACCAAAAAAGCAGTAACCTAACTGTGGAACAGTTCAGGATCTTTAGACTTGA TACTTTTCTTGATTTCCCTTAGGGGTCAAAGTTCACAAGGAAAATAGCCCTTTAGTGGGA AACTGAAACAGGCTTGTTTTTATTTACTATTTACTCATATTTGTAATGCAATTAAAATAT ATGTTGTTAACTTTTTTTTTTTTTTCTCAAGAGCTCGGTTGATAAAACCAGGGGTATGTG GACTTTTTGAGTCTGTGCCTTTTGGGGGTGTGTATGGGAATGTTATGTTTTAACATTTTT TACAAAATAGTATTGTCTTTTTAATTTATTCGTTAGTGGTTTGCACAAGGAAGATAATCG ATAGTCATGTTTTTTAGACGCTCTGTATTGCTTGGTAAGCTACGTAGTAAAAAATGTTTA CTTTTCCTTAAATGTTTTGAATTTCGGGGTTATGAAATTTGTTGAGTAATTTTTAGACAG TCACATCTTGTTGACTGGAGGCATCTAGTGGAAAAATGCAGTATTTCAGCCTGATTGTGT TTGAAGTAAATGATTAAAAGAGGAGGAAGTTACCACAAAAAAAAAAAAAAAAAAAAA
Restriction Sites	Please inquire
ACCN	BC016934
Insert Size	1600 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	The ORF of this clone has been fully sequenced and found to be a perfect match to BC016934.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC016934.1, AAH16934.1
RefSeq Size	1617 bp
RefSeq ORF	1617 bp
Locus ID	6648
Domains	sodfe
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Huntington's disease
Gene Summary	This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]

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