NUR77 (NR4A1) (NM_173158) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	Gfrp; GFRP1; Hbr-1; Hbr1; Hmr; HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77, MGC9485; hormone receptor; N10; NGFI-B; NGFIB; NP10; nuclear receptor subfamily 4, group A, member 1; nur77; TIS1; TR3
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene ORF sequence for NM_173158 edited ACGAAACTTGGGGGAGTGCACAGAAGAACTTCGGGAGCGCACGCGGGACCAGGGACCAGG CTGAGACTCGGGGCGCCAGTCCGGGCAGGGGCAGCGGGAGCCGGCCGGAGATGCCCTGTA TCCAAGCCCAATATGGGACACCAGCACCGAGTCCGGGACCCCGTGACCACCTGGCAAGCG ACCCCCTGACCCCTGAGTTCATCAAGCCCACCATGGACCTGGCCAGCCCCGAGGCAGCCC CCGCTGCCCCCACTGCCCTGCCCAGCTTCAGCACCTTCATGGACGGCTACACAGGAGAGT TTGACACCTTCCTCTACCAGCTGCCAGGAACAGTCCAGCCATGCTCCTCAGCCTCCTCCT CGGCCTCCTCCACATCCTCGTCCTCAGCCACCTCCCCTGCCTCTGCCTCCTTCAAGTTCG AGGACTTCCAGGTGTACGGCTGCTACCCCGGCCCCCTGAGCGGCCCAGTGGATGAGGCCC TGTCCTCCAGTGGCTCTGACTACTATGGCAGCCCCTGCTCGGCCCCGTCGCCCTCCACGC CCAGCTTCCAGCCGCCCCAGCTCTCTCCCTGGGATGGCTCCTTCGGCCACTTCTCGCCCA GCCAGACTTACGAAGGCCTGCGGGCATGGACAGAGCAGCTGCCCAAAGCCTCTGGGCCCC CACAGCCTCCAGCCTTCTTTTCCTTCAGTCCTCCCACCGGCCCCAGCCCCAGCCTGGCCC AGAGCCCCCTGAAGTTGTTCCCCTCACAGGCCACCCACCAGCTGGGGGAGGGAGAGAGCT ATTCCATGCCTACGGCCTTCCCAGGTTTGGCACCCACTTCTCCACACCTTGAGGGCTCGG GGATACTGGATACACCCGTGACCTCAACCAAGGCCCGGAGCGGGGCCCCAGGTGGAAGTG AAGGCCGCTGTGCTGTGTGTGGGGACAACGCTTCATGCCAGCATTATGGTGTCCGCACAT GTGAGGGCTGCAAGGGCTTCTTCAAGGTACCGCGCAGCCCCAGGTGGGGCCTTTTGTTGG AAATGGAGAGAGGCTGGCCTCATCCCATTGGGACCTGTGGTCTCCCCCTGGGTTCTCCTC CTAGCTAAGTCCTGTCCTGCAGGGTGGGATCAGCCCTGCCAGGTGGGCCGCCTTCCTGGA GACCCGTAGATGCCAGGGCTGGAAGCTTTCATTTGCCGGGACACTCGGGCCCATGGGATT GCACAGAGCTGGAGGGAGGGGTGAGATAGGGGCAGATAGGAGCTGCAGGGGTGCCTGGCG AGCCTCTGGTTTTCCTCTGCTCCTCTGCCTGTCCTCTCCCAACTCAAGGTTCTAGTGGGA AGGGGTGCCCCCAGGCTCTCATGTTCCTGGCGTGAGATGAAAGGATCCCTGCGGAGGGTT TGGTTCTTGAGGGCTGGGGGTGGACTTGGGAACAGGCTGTGTGTTTGTCCCAGCGATGGT GCCTGCTTAGCTTCCCGTCCCCACCCCCCAGCCCCTTGGCCCTCTCCTGTCTGCCCTAGG GAGAAGGCAGGTGGACAAGGGCCCATGAAAAAATACAGGTGTCTAGACTGCCAGGGAGAC CCTGGCCCCCAGTAGTGTGTCCTGGGGACTTCCTCAGAGCGAGAAACCTCCCCCAATGTC TTCAAGACTTTTCTCTCCCCCCGCCCAACCCCGTCTCTCCCTCCCTTGCCACCCAAATGT TAGAAAAATAGCTGTGAACAGAGAGCGCTTTTGTCTGCAATGGCAGCAGGATCTGGACGG TCCCCTCCCC
Restriction Sites	Please inquire
ACCN	NM_173158
Insert Size	1800 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference, NM_173158.1.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_173158.1, NP_775181.1
RefSeq Size	1842 bp
RefSeq ORF	1842 bp
Locus ID	3164
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways	MAPK signaling pathway
Gene Summary	This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] Transcript Variant: This variant (3), also known as TRCbeta, contains multiple differences compared to variant 1. The resulting isoform (b) contains a shorter and distinct C-terminus compared to isoform a.

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