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SH2B2 (NM_020979) Human Untagged Clone
CAT＃: SC314274
SH2B2 (untagged)-Human SH2B adaptor protein 2 (SH2B2)
CNY 4,712.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APS |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_020979 edited
GAGGCGCTCTGCCGCCGGCCCCTCCTCACTTCTTCCTCCCTGGGGATGGATCCAAGCTAT TGTCCTGCCCATGGCTTCCCATCTCAGGACCCTCTCTGGCCGCTATCATCCCAGCAGTGG AGTTCAGCCCACTACTCTGAACCAGCCGCAGGTGGCTGCGATGGGACGGAAGCCATGAAT GGTGCCGGCCCTGGCCCCGCCGCAGCCGCCCCGGTCCCAGTCCCGGTCCCGGTCCCGGAC TGGCGGCAGTTCTGCGAGCTGCATGCGCAGGCGGCCGCCGTGGACTTTGCGCACAAGTTC TGCCGTTTCCTGCGGGACAACCCAGCTTACGACACGCCCGACGCCGGCGCCTCCTTCTCC CGCCACTTCGCCGCCAACTTCCTGGACGTCTTCGGCGAGGAGGTGCGCCGCGTGCTGGTG GCTGGGCCGACGACTCGGGGCGCGGCCGTGAGCGCAGAGGCCATGGAGCCGGAGCTCGCG GACACCTCTGCACTCAAGGCGGCGCCCTACGGCCACTCGCGGAGCTCGGAGGACGTGTCC ACGCACGCGGCCACCAAGG:CCCGCGTTCGCAAGGGCTTCTCGCTGCGCAACATGAGCCT GTGCGTGGTGGACGGCGTGCGCGACATGTGGCACCGGCGCGCCTCGCCCGAGCCCGACGC GGCAGCTGCCCCGCGCACCGCCGAGCCCCGCGACAAGTGGACGCGGCGCCTGAGGCTGTC GCGGACGCTGGCTGCCAAGGTGGAGCTGGTGGACATTCAACGCGAGGGGGCGCTGCGCTT CATGGTGGCCGACGACGCGGCCGCGGGCTCCGGGGGCTCGGCTCAGTGGCAGAAGTGCCG CCTGCTCCTGCGCAGGGCTGTGGCCGAGGAACGCTTCCGCCTGGAGTTCTTCGTGCCGCC CAAAGCCTCCAGGCCCAAGGTCAGCATCCCACTGTCAGCCATCATTGAGGTCCGCACCAC CATGCCCCTGGAAATGCCAGAGAAGGATAACACATTCGTCCTCAAGGTAGAGAATGGAGC CGAATACATCTTGGAGACCATCGACTCTCTGCAGAAGCACTCGTGGGTAGCTGACATCCA GGGCTGCGTGGACCCCGGTGACAGTGAGGAAGACACCGAGCTCTCCTGTACCCGAGGAGG CTGTCTGGCCAGCCGCGTGGCCTCCTGCAGCTGTGAGCTCCTGACTGATGTCGACCTGCC CCGCCCCCCAGAGACGACAGCCGTGGGTGCAGTGGTGACAGCCCCCCACAGCCGAGGTCG AGATGCCGTCAGAGAATCCCTGATCCACGTCCCGCTAGAGACCTTTCTGCAGACCCTGGA ATCCCCGGGCGGCAGCGGCAGTGACAGCAATAACACAGGGGAACAGGGTGCAGAGACGGA TCCCGAGGCTGAACCCGAGCTGGAGCTATCCGACTACCCATGGTTCCACGGGACACTGTC CCGGGTCAAGGCTGCTCAACTGGTTCTGGCAGGGGGGCCCCGGAACCACGGCCTCTTCGT GATCCGCCAAAGTGAGACTCGGCCTGGGGAGTACGTGCTGACCTTCAACTTCCAGGGCAA GGCCAAGCACCTGCGCCTGTCCCTGAACGGCCACGGCCAGTGTCACGTACAGCATCTGTG GTTCCAGTCTGTGCTTGACATGCTCCGCCACTTCCACACACACCCCATCCCACTGGAGTC AGGGGGCTCGGCCGACATCACCCTTCGCAGCTATGTGCGGGCCCAGGACCCCCCACCAGA GCCGGGCCCCACGCCCCCTGCCGCGCCCGCGTCCCCGGCCTGCTGGAGCGACTCGCCCGG CCAGCACTACTTCTCCAGCCTCGCCGCGGCCGCCTGCCCGCCTGCCTCGCCCTCCGACGC CGCCGGCGCCTCCTCGTCTTCCGCCTCGTCGTCCTCTGCCGCGTCGGGGCCCGCCCCCCC GCGCCCCGTCGAGGGCCAGCTCAGCGCGCGGAGCCGCAGCAACAGCGCCGAGCGCCTGCT GGAGGCCGTGGCCGCCACCGCCGCCGAGGAGCCCCCGGAGGCCGCGCCCGGCCGCGCGCG CGCCGTGGAGAACCAGTACTCCTTCTACTAGCCCGCGGCGCCGCCCGGGTGGGACACGCC AAGCTCTTCAGTGAAGACACGATGTTATTAAAAGCCTGTTTTAGGGACTGCAAAAAAAAA AAAAAAAAA >OriGene 5' read for NM_020979 unedited
GGTTCAAATTTTGTATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGGAGGCGC TCTGCCGCCGGCCCCTCCTCACTTCTTCCTCCCTGGGGATGGATCCAAGCTATTGTCCTG CCCATGGCTTCCCATCTCAGGACCCTCTCTGGCCGCTATCATCCCAGCAGTGGAGTTCAG CCCACTACTCTGAACCAGCCGCAGGTGGCTGCGATGGGACGGAAGCCATGAATGGTGCCG GCCCTGGCCCCGCCGCAGCCGCCCCGGTCCCAGTCCCGGTCCCGGTCCCGGACTGGCGGC AGTTCTGCGAGCTGCATGCGCAGGCGGCCGCCGTGGACTTTGCGCACAAGTTCTGCCGTT TCCTGCGGGACAACCCAGCTTACGACACGCCCGACGCCGGCGCCTCCTTCTCCCGCCACT TCGCCGCCAACTTCCTGGACGTCTTCGGCGAGGAGGTGCGCCGCGTGCTGGTGGCTGGGC CGACGACTCGGGGCGCGGCCGTGAGCGCAGAGGCCATGGAGCCGGAGCTCGCGGACACCT CTGCACTCAAGGCGGCGCCCTACGGCCACTCGCGGAGCTCGGAGGACGTGTCCACGCACG CGGCCACCAAGGCCCGCGTTCGCAAGGGCTTCTCGCTGCGCAACATGAGCCTGTGCGTGG TGGACGGCGTGCGCGACATGTGGCACCGGCGCGCCTCGCCCGAGCCCGACGCGGCAGCTG CCCCGCGCACCGTCGAGCCCCGCGACAAGTGGACGCGGCGCCTGAGGCTGTCGCGGACGC TGGCTGCCAGGTGGAGCTGGTGGACATTCACGCGAGGGGCGCTGCGCTTCATGGTGGCCG ACGACGCGCCGCGGCTNCGGGGGCTCGGCTCAATGGCAGAAATGCCGCCTGCTCTGCGCA GGGCTGN >OriGene 3' read for NM_020979 unedited
GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCAGTCCCTAAAACAGGCTTTTA ATAACATCGTGTCTTCACTGAAGAGCTTGGCGTGTCCCACCCGGGCGGCGCCGCGGGCTA GTAGAAGGAGTACTGGTTCTCCACGGCGCGCGCGCGGCCGGGCGCGGCCTCCGGGGGCTC CTCGGCGGCGGTGGCGGCCACGGCCTCCAGCAGGCGCTCGGCGCTGTTGCTGCGGCTCCG CGCGCTGAGCTGGCCCTCGACGGGGCGCGGGGGGGCGGGCCCCGACGCGGCAGAGGACGA CGAGGCGGAAGACGAGGAGGCGCCGGCGGCGTCNGAGGGCGAGGCANGCGGGCAGGCGGC CGCGGCGAGGCTGGAGAAGTANTGCTGGCCGGGCGAGTCGCTCCAACAGGCCGGGGACGC GGGCGCGGCAGGGGGCGTGGGGCCCGGCTCTGGTGGGGGGTCCTGGGCCCGCACATAGCT GCGAAGGGTGATGTCGGCCGAGCCCCCTGACTCCANTGGGATGGGGTGTGTGTGGAAATG GCGGACCATGTCAAGCACAGACTGGAACCACAGATGCTGTACGTGACACTGGCCGTGGCC GTTCAGGGACAGGCGCAGGTGCTTGGCCTTGCCCTGGAGTTGAAGGTCAACACGTACTCC CCCAGCCGAGTCTCACTTTGGGCGATCACGAAGAAGCCGGGGTTCCCGGGGCCCCCCTGC CAGAACCAGTTGAGCACCCTTGACCCCGGACATGGTCCCCTGGAACCATTGGTAATCCGG ATACTTCCAGCTTGGGGTTCACCCTTGGGAATCCCGTCTTTTGACCTTGTTCCCCTTGGG TAATGGCTGCAACTGCCCGNTCGCCCTCCGGGGATTCCAAGGCCCCCAAAAAAGGTTTTA CGGGTACCGGGATAAGGATCTCTTTCCCCCATCTTCCCCCGCTGGGGGGGCCTGTTCTCC GTCCCCCGCCCCCCCTTCGGGGCCCCGCCC |
| Restriction Sites | Please inquire |
| ACCN | NM_020979 |
| Insert Size | 2200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain 3bp deletion. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_020979.1, NP_066189.1 |
| RefSeq Size | 2110 bp |
| RefSeq ORF | 1899 bp |
| Locus ID | 10603 |
| UniProt ID | O14492 |
| Domains | SH2, PH |
| Protein Families | Druggable Genome |
| Protein Pathways | Insulin signaling pathway, Neurotrophin signaling pathway |
| Gene Summary | The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC229333 | SH2B2 (Myc-DDK-tagged)-Human SH2B adaptor protein 2 (SH2B2) |
CNY 4,944.00 |
|
| RC229333L3 | Lenti ORF clone of Human SH2B adaptor protein 2 (SH2B2), Myc-DDK-tagged |
CNY 9,120.00 |
|
| RC229333L4 | Lenti ORF clone of Human SH2B adaptor protein 2 (SH2B2), mGFP tagged |
CNY 9,120.00 |
|
| RG229333 | SH2B2 (tGFP-tagged) - Human SH2B adaptor protein 2 (SH2B2) |
CNY 7,980.00 |
|
| SC327968 | SH2B2 (untagged)-Human SH2B adaptor protein 2 (SH2B2) |
CNY 13,110.00 |
