ZCCHC8 (AK027702) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6 series
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AK027702, the custom clone sequence may differ by one or more nucleotides ATGGCCGCAGAGGTGTATTTTGGCGATCTAGAGCTCTTCGAGCCGTTCGACCACCCAGGG GAGTCGATTCCGAAGCCCGTTCACACTCGCTTCAAGGACGACGACGGCGACGAGGAGGAC GAAAATGGGGTCGGCGACGCGGAGCTACGGGAGCGGCTTCGGCAGTGCGAGGAGACCATC GAGCAGCTCCGCGCCGAGAATCAAGAACTTAAACGAAAATTGAACATTCTGACTCGACCG AGTGGAATATTGGTGAACGATACTAAGTTAGATGGACCTATATTACAGATTCTATTCATG AACAATGCTATTTCAAAGCAATATCATCAAGAAATAGAGGAATTTGTATCAAATTTAGTA AAAAGATTTGAGGAACAGCAGAAAAATGATGTGGAAAAGACTTCCTTTAATCTTTTGCCC CAGCCATCCAGTATTGTGCTAGAGGAGGACCACAAAGTGGAAGAGTCCTGTGCCATTAAA AACAACAAGGAAGCTTTCAGTGTTGTAGGAAGTGTCCTGTATTTTACTAATTTTTGCCTT GATAAATTGGGGCAACCGCTTCTAAATGAAAACCCTCAGCTTTCCGAAGGATGGGAAATA CCCAAGTACCATCAAGTCTTCAGCCACATTGTTTCTCTAGAAGGGCAAGAAATACAAGTA AAGGCAAAAAGGCCAAAGCCTCACTGTTTCAATTGTGGTTCTGAAGAACACCAAATGAAA GATTGCCCAATGCCTCGGAATGCTGCTCGAATAAGTGAAAAGAGAAAAGAGTATATGGAT GCCTGTGGAGAAGCAAACAATCAGAATTTCCAGCAGCGATACCACGCAGAAGAAGTAGAA GAAAGATTTGGAAGATTCAAGCCAGGAGTTATTAGTGAGGAACTTCAAGATGCACTAGGT GTGACAGACAAGAGTCTTCCACCTTTTATCTATCGGATGCGCCAGCTAGGGTACCCACCA GGGTGGCTCAAAGAGGCTGAATTGGAGAATTCGGGGCTTGCACTCTATGATGGAAAAGAT GGCACTGATGGGGAAACAGAAGTTGGAGAAATACAACAGAATAAAAGTGTCACTTACGAT CTCTCAAAATTGGTCAACTATCCTGGTTTTAATATATCTACTCCCAGAGGAATTCCAGAC GAATGGAGGATCTTTGGTTCCATACCAATGCAGGCATGTCAGCAGAAGGATGTGTTTGCC AATTACCTTACTTCTAACTTCCAAGCGCCAGGTGTGAAGTCTGGCAACAAGAGGTCTTCA TCTCACTCTAGCCCAGGTAGTCCAAAGAAGCAGAAGAATGAAAGCAACTCAGCGGGATCT CCCGCCGACATGGAGCTCGATTCAGATATGGAGGTACCACATGGTTCTCAGAGCAGCGAA GGTTTTCAGTTTCAACCACCATTACCTCCTGACACTCCTCCACTCCCCCGGGGAACTCCT CCACCCGTCTTCACCCCTCCACTCCCAAAGGGCACCCCGCCGCTGACTCCCAGTGACTCA CCCCAGACCAGAACAGCATCTGGAGCTGTGGATGAGGACGCACTGACTCTAGAAGAACTT GAAGAACAGCAGAGGCGGATCTGGGCAGCTCTTGAGCAGGCCGAGAGCGTAAACAGCGAC TCCGACGTTCCTGTGGACACACCTTTAACTGGCAATTCCGTTGCCTCATCACCTTGTCCA AATGAGCTAGACCTCCCTGTCCCGGAGGGAAAAACATCTGAAAAGCAGACGCTGGATGAG CCTGAGGTACCAGAGATTTTTACAAAGAAATCAGAAGCTGGACATGCCTCCAGTCCAGAC TCTGAGGTGACATCACTTTGTCAGAAGGAAAAAGCAGAGTTGGCTCCGGTAAACACTGAA GGTGCCCTTCTTGATAATGGCAGTGTCGTACCAAACTGTGACATCAGCAATGGGGGCAGC CAGAAGCTCTTTCCTGCAGACACCAGTCCTTCAACGGCCACTAAAATTCATAGCCCTATA CCTGACATGAGCAAATTTGCAACTGGAATCACGCCATTTGAATTTGAGAATATGGCAGAA TCTACTGGAATGTACCTCAGGATAAGAAGCTTGTTAAAGAACTCACCCCGAAACCAGCAG AAAAACAAAAAGGCCTCTGAA
Restriction Sites	Please inquire
ACCN	AK027702
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	AK027702.1, BAB55308.1
RefSeq Size	2603 bp
RefSeq ORF	2124 bp
Locus ID	55596
Domains	zf-CCHC, PSP
Gene Summary	This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.