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MTRR (NM_024010) Human Untagged Clone
CAT＃: SC314547
MTRR (untagged)-Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2
CNY 5,320.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | cblE; MSR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_024010 edited
GGAGCTTTCTATTGGTCCTGGGTACCGAGCATGGGCGCTGCGTCAGTGCGCGCTGGCGCA AGGTTGGTGGAAGTCGCGTTGTGCAGTTTCACTGTTACATGCCTTGAAGTGATGAGGAGG TTTCTGTTACTATATGCTACACAGCAGGGACAGGCAAAGGCCATCGCAGAAGAAATATGT GAGCAAGCTGTGGTACATGGATTTTCTGCAGATCTTCACTGTATTAGTGAATCCGATAAG TATGACCTAAAAACCGAAACAGCTCCTCTTGTTGTTGTGGTTTCTACCACGGGCACCGGA GACCCACCCGACACAGCCCGCAAGTTTGTTAAGGAAATACAGAACCAAACACTGCCGGTT GATTTCTTTGCTCACCTGCGGTATGGGTTACTGGGTCTCGGTGATTCAGAATACACCTAC TTTTGCAATGGGGGGAAGATAATTGATAAACGACTTCAAGAGCTTGGAGCCCGGCATTTC TATGACACTGGACATGCAGATGACTGTGTAGGTTTAGAACTTGTGGTTGAGCCGTGGATT GCTGGACTCTGGCCAGCCCTCAGAAAGCATTTTAGGTCAAGCAGAGGACAAGAGGAGATA AGTGGCGCACTCCCGGTGGCATCACCTGCATCCTTGAGGACAGACCTTGTGAAGTCAGAG CTGCTACACATTGAATCTCAAGTCGAGCTTCTGAGATTCGATGATTCAGGAAGAAAGGAT TCTGAGGTTTTGAAGCAAAATGCAGTGAACAGCAACCAATCCAATGTTGTAATTGAAGAC TTTGAGTCCTCACTTACCCGTTCGGTACCCCCACTCTCACAAGCCTCTCTGAATATTCCT GGTTTACCCCCAGAATATTTACAGGTACATCTGCAGGAGTCTCTTGGCCAGGAGGAAAGC CAAGTATCTGTGACTTCAGCAGATCCAGTTTTTCAAGTGCCAATTTCAAAGGCAGTTCAA CTTACTACGAATGATGCCATAAAAACCACTCTGCTGGTAGAATTGGACATTTCAAATACA GACTTTTCCTATCAGCCTGGAGATGCCTTCAGCGTGATCTGCCCTAACAGTGATTCTGAG GTACAAAGCCTACTCCAAAGACTGCAGCTTGAAGATAAAAGAGAGCACTGCGTCCTTTTG AAAATAAAGGCAGACACAAAGAAGAAAGGAGCTACCTTACCCCAGCATATACCTGCGGGA TGTTCTCTCCAGTTCATTTTTACCTGGTGTCTTGAAATCCGAGCAATTCCTAAAAAGGCA TTTTTGCGAGCCCTTGTGGACTATACCAGTGACAGTGCTGAAAAGCGCAGGCTACAGGAG CTGTGCAGTAAACAAGGGGCAGCCGATTATAGCCGCTTTGTACGAGATGCCTGTGCCTGC TTGTTGGATCTCCTCCTCGCTTTCCCTTCTTGCCAGCCACCACTCAGTCTCCTGCTCGAA CATCTTCCTAAACTTCAACCCAGACCATATTCGTGTGCAAGCTCAAGTTTATTTCACCCA GGAAAGCTCCATTTTGTCTTCAACATTGTGGAATTTCTGTCTACTGCCACAACAGAGGTT CTGCGGAAGGGAGTATGTACAGGCTGGCTGGCCTTGTTGGTTGCTTCAGTTCTTCAGCCA AACATACATGCATCCCATGAAGACAGCGGGAAAGCCCTGGCTCCTAAGATATCCATCTCT CCTCGAACAACAAATTCTTTCCACTTACCAGATGACCCCTCAATCCCCATCATAATGGTG GGTCCAGGAACCGGCATAGCCCCGTTTATTGGGTTCCTACAACATAGAGAGAAACTCCAA GAACAACACCCAGATGGAAATTTTGGAGCAATGTGGTTGTTTTTTGGCTGCAGGCATAAG GATAGGGATTATCTATTCAGAAAAGAGCTCAGACATTTCCTTAAGCATGGGATCTTAACT CATCTAAAGGTTTCCTTCTCAAGAGATGCTCCTGTTGGGGAGGAGGAAGCCCCAGCAAAG TATGTRCAAGACAACATCCAGCTTCATGGCCAGCAGGTGGCAAGAATCCTCCTCCAGGAG AACGGCCATATTTATGTGTGTGGAGATGCAAAGAATATGGCCAAGGATGTACATGATGCC CTTGTGCAAATAATAAGCAAAGAGGTTGGAGTTGAAAAACTAGAAGCAATGAAAACCCTG GCCACTTTAAAAGAAGAAAAACGCTACCTTCAGGATATTTGGTCATAAAACCAGAAATTA AAGAAAGAGGATTAAGCTTTTTTGACTGAAAGTACTAAAAGTCAGCTTTACTAGTGCCAA ACCTTTAAATTTTCAAAAGAAAATTTTCTTTCAACATTTCTTGAAGGACATGGAGTGGAG ATTGGATCATTTAACAATATAACAAAACTTCCTGATTTGATTTTACGTATCTTCTATCTA CGCCCTTCCTGTGCCTGTGACTCTCCCCA |
| Restriction Sites | Please inquire |
| ACCN | NM_024010 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_024010.1, NP_076915.1 |
| RefSeq Size | 3291 bp |
| RefSeq ORF | 2178 bp |
| Locus ID | 4552 |
| UniProt ID | Q9UBK8 |
| Domains | flavodoxin, NAD_binding_1, FAD_binding_1 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 6. Variants 1, 2, 6, 7, and 8 all encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212032 | MTRR (Myc-DDK-tagged)-Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2 |
CNY 5,312.00 |
|
| RC212032L1 | Lenti ORF clone of Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC212032L2 | Lenti ORF clone of Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC212032L3 | Lenti ORF clone of Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC212032L4 | Lenti ORF clone of Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG212032 | MTRR (tGFP-tagged) - Human 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2 |
CNY 6,912.00 |
