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MSH5 (NM_025259) Human Untagged Clone
CAT＃: SC314816
MSH5 (untagged)-Human mutS homolog 5 (E. coli) (MSH5), transcript variant 1
CNY 10,744.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | G7; MUTSH5; NG23; POF13 |
| Vector | PCMV6-Neo |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_025259, the custom clone sequence may differ by one or more nucleotides
ATGGCCTCCTTAGGAGCGAACCCAAGGAGGACACCGCAGGGACCGAGACCTGGGGCGGCC TCCTCCGGCTTCCCCAGCCCGGCCCCAGTGCCGGGCCCCAGGGAGGCCGAGGAGGAGGAA GTCGAGGAGGAGGAGGAGCTGGCCGAGATCCATCTGTGTGTGCTGTGGAATTCAGGATAC TTGGGCATTGCCTACTATGATACTAGTGACTCCACTATCCACTTCATGCCAGATGCCCCA GACCACGAGAGCCTCAAGCTTCTCCAGAGAGTTCTGGATGAGATCAATCCCCAGTCTGTT GTTACGAGTGCCAAACAGGATGAGAATATGACTCGATTTCTGGGAAAGCTTGCCTCCCAG GAGCACAGAGAGCCTAAAAGACCTGAAATCATATTTTTGCCAAGTGTGGATTTTGGTCTG GAGATAAGCAAACAACGCCTCCTTTCTGGAAACTACTCCTTCATCCCAGACGCCATGACT GCCACTGAGAAAATCCTCTTCCTCTCTTCCATTATTCCCTTTGACTGCCTCCTCACACCC CCAGGAGATTTAAGATTTACCCCGATTCCACTGCTGATCCCCTCCCAGGTTCGAGCACTT GGAGGGCTGCTGAAGTTCCTGGGTCGAAGAAGAATCGGGGTTGAACTGGAAGACTATAAT GTCAGCGTCCCCATCCTGGGCTTTAAGAAATTTATGTTGACTCATCTGGTGAACATAGAT CAAGACACTTACAGTGTTCTACAGATTTTTAAGAGTGAGTCTCACCCCTCAGTGTACAAA GTGGCCAGTGGACTGAAGGAGGGGCTCAGCCTCTTTGGAATCCTCAACAGATGCCACTGT AAGTGGGGAGAGAAGCTGCTCAGGCTATGGTTCACACGTCCGACTCATGACCTGGGGGAG CTCAGTTCTCGTCTGGACGTCATTCAGTTTTTTCTGCTGCCCCAGAATCTGGACATGGCT CAGATGCTGCATCGGCTCCTGGGTCACATCAAGAACGTGCCTCTGATTCTGAAACGCATG AAGTTGTCCCACACCAAGGTCAGCGACTGGCAGGTTCTCTACAAGACTGTGTACAGTGCC CTGGGCCTGAGGGATGCCTGCCGCTCCCTGCCGCAGTCCATCCAGCTCTTTCGGGACATT GCCCAAGAGTTCTCTGATGACCTGCACCATATCGCCAGCCTCATTGGGAAAGTAGTGGAC TTTGAGGGCAGCCTTGCTGAAAATCGCTTCACAGTCCTCCCCAACATAGATCCTGAAATT GATGAGAAAAAGCGAAGACTGATGGGACTTCCCAGTTTCCTTACTGAGGTTGCCCGCAAG GAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGTCATCTACATCCCTCTGATT GGCTTCCTTCTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATT AATGGACTGGACTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGTAGTGCCCGAACC AAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGATCCGGGACCAGGAGACGCTG CTGATGTACCAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTG GACCTTGCCTCCCGCCTGGACGTCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGC TACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACGAATCCAGAATGGCAGACAT CCTCTGATGGAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGAC AAAGGGAGGGTCAAAGTCATCACTGGACCCAACTCATCAGGGAAGAGCATATACCTCAAA CAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTTTGTGCCAGCAGAGGAGGCC GAAATTGGGGCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTT GGCCTCTCCACCTTCATGATCGACCTCAACCAGGTGGCGAAAGCAGTGAACAATGCCACT GCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAACCAACACGGTGGATGGGCTC GCGCTTCTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATC TTTGTGGCCACCAACTTTCTGAGCCTTGTTCAGCTACAACTGCTGCCACAAGGGCCCCTG GTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGATCTTGTCTTCTTCTATCAG GTTTGCGAAGGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTT CCTGACAAGCTTGTGGCTCGTGGCAAGGAGGTCTCAGACTTGATCCGCAGTGGAAAACCC ATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGAAAATTGCCAGACATTAGTG GATAAGTTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGC CAGGAAGTGCTGCCTGCTGCCACCAGCATCCTC |
| Restriction Sites | Please inquire |
| ACCN | NM_025259 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_025259.3, NP_079535.3 |
| RefSeq Size | 4019 bp |
| RefSeq ORF | 2751 bp |
| Locus ID | 4439 |
| UniProt ID | O43196 |
| Domains | MutS_V, MutS_III, MutS_IV |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011] Transcript Variant: This variant (1) represents the shortest transcript and encodes the shortest isoform (a). |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224044 | MSH5 (Myc-DDK-tagged)-Human mutS homolog 5 (E. coli) (MSH5), transcript variant 1 |
CNY 5,800.00 |
|
| RC224044L3 | Lenti-ORF clone of MSH5 (Myc-DDK-tagged)-Human mutS homolog 5 (E. coli) (MSH5), transcript variant 1 |
CNY 7,700.00 |
|
| RC224044L4 | Lenti-ORF clone of MSH5 (mGFP-tagged)-Human mutS homolog 5 (E. coli) (MSH5), transcript variant 1 |
CNY 7,700.00 |
|
| RG224044 | MSH5 (tGFP-tagged) - Human mutS homolog 5 (E. coli) (MSH5), transcript variant 1 |
CNY 6,370.00 |
