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Fibrinogen alpha chain (FGA) (NM_000508) Human Untagged Clone
CAT＃: SC314840
FGA (untagged)-Human fibrinogen alpha chain (FGA), transcript variant alpha-E
CNY 16,720.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Fib2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC314840 representing NM_000508.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTTTTCCATGAGGATCGTCTGCCTGGTCCTAAGTGTGGTGGGCACAGCATGGACTGCAGATAGTGGT GAAGGTGACTTTCTAGCTGAAGGAGGAGGCGTGCGTGGCCCAAGGGTTGTGGAAAGACATCAATCTGCC TGCAAAGATTCAGACTGGCCCTTCTGCTCTGATGAAGACTGGAACTACAAATGCCCTTCTGGCTGCAGG ATGAAAGGGTTGATTGATGAAGTCAATCAAGATTTTACAAACAGAATAAATAAGCTCAAAAATTCACTA TTTGAATATCAGAAGAACAATAAGGATTCTCATTCGTTGACCACTAATATAATGGAAATTTTGAGAGGC GATTTTTCCTCAGCCAATAACCGTGATAATACCTACAACCGAGTGTCAGAGGATCTGAGAAGCAGAATT GAAGTCCTGAAGCGCAAAGTCATAGAAAAAGTACAGCATATCCAGCTTCTGCAGAAAAATGTTAGAGCT CAGTTGGTTGATATGAAACGACTGGAGGTGGACATTGATATTAAGATCCGATCTTGTCGAGGGTCATGC AGTAGGGCTTTAGCTCGTGAAGTAGATCTGAAGGACTATGAAGATCAGCAGAAGCAACTTGAACAGGTC ATTGCCAAAGACTTACTTCCCTCTAGAGATAGGCAACACTTACCACTGATAAAAATGAAACCAGTTCCA GACTTGGTTCCCGGAAATTTTAAGAGCCAGCTTCAGAAGGTACCCCCAGAGTGGAAGGCATTAACAGAC ATGCCGCAGATGAGAATGGAGTTAGAGAGACCTGGTGGAAATGAGATTACTCGAGGAGGCTCCACCTCT TATGGAACCGGATCAGAGACGGAAAGCCCCAGGAACCCTAGCAGTGCTGGAAGCTGGAACTCTGGGAGC TCTGGACCTGGAAGTACTGGAAACCGAAACCCTGGGAGCTCTGGGACTGGAGGGACTGCAACCTGGAAA CCTGGGAGCTCTGGACCTGGAAGTACTGGAAGCTGGAACTCTGGGAGCTCTGGAACTGGAAGTACTGGA AACCAAAACCCTGGGAGCCCTAGACCTGGTAGTACCGGAACCTGGAATCCTGGCAGCTCTGAACGCGGA AGTGCTGGGCACTGGACCTCTGAGAGCTCTGTATCTGGTAGTACTGGACAATGGCACTCTGAATCTGGA AGTTTTAGGCCAGATAGCCCAGGCTCTGGGAACGCGAGGCCTAACAACCCAGACTGGGGCACATTTGAA GAGGTGTCAGGAAATGTAAGTCCAGGGACAAGGAGAGAGTACCACACAGAAAAACTGGTCACTTCTAAA GGAGATAAAGAGCTCAGGACTGGTAAAGAGAAGGTCACCTCTGGTAGCACAACCACCACGCGTCGTTCA TGCTCTAAAACCGTTACTAAGACTGTTATTGGTCCTGATGGTCACAAAGAAGTTACCAAAGAAGTGGTG ACCTCCGAAGATGGTTCTGACTGTCCCGAGGCAATGGATTTAGGCACATTGTCTGGCATAGGTACTCTG GATGGGTTCCGCCATAGGCACCCTGATGAAGCTGCCTTCTTCGACACTGCCTCAACTGGAAAAACATTC CCAGGTTTCTTCTCACCTATGTTAGGAGAGTTTGTCAGTGAGACTGAGTCTAGGGGCTCAGAATCTGGC ATCTTCACAAATACAAAGGAATCCAGTTCTCATCACCCTGGGATAGCTGAATTCCCTTCCCGTGGTAAA TCTTCAAGTTACAGCAAACAATTTACTAGTAGCACGAGTTACAACAGAGGAGACTCCACATTTGAAAGC AAGAGCTATAAAATGGCAGATGAGGCCGGAAGTGAAGCCGATCATGAAGGAACACATAGCACCAAGAGA GGCCATGCTAAATCTCGCCCTGTCAGAGACTGTGATGATGTCCTCCAAACACATCCTTCAGGTACCCAA AGTGGCATTTTCAATATCAAGCTACCGGGATCCAGTAAGATTTTTTCTGTTTATTGCGATCAAGAGACC AGTTTGGGAGGATGGCTTTTGATCCAGCAAAGAATGGATGGATCACTGAATTTTAACCGGACCTGGCAA GACTACAAGAGAGGTTTCGGCAGCCTGAATGACGAGGGGGAAGGAGAATTCTGGCTAGGCAATGACTAC CTCCACTTACTAACCCAAAGGGGCTCTGTTCTTAGGGTTGAATTAGAGGACTGGGCTGGGAATGAAGCT TATGCAGAATATCACTTCCGGGTAGGCTCTGAGGCTGAAGGCTATGCCCTCCAAGTCTCCTCCTATGAA GGCACTGCGGGTGATGCTCTGATTGAGGGTTCCGTAGAGGAAGGGGCAGAGTACACCTCTCACAACAAC ATGCAGTTCAGCACCTTTGACAGGGATGCAGACCAGTGGGAAGAGAACTGTGCAGAAGTCTATGGGGGA GGCTGGTGGTATAATAACTGCCAAGCAGCCAATCTCAATGGAATCTACTACCCTGGGGGCTCCTATGAC CCAAGGAATAACAGTCCTTATGAGATTGAGAATGGAGTGGTCTGGGTTTCCTTTAGAGGGGCAGATTAT TCCCTCAGGGCTGTTCGCATGAAAATTAGGCCCCTTGTGACCCAATAG AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGAT ATCCTGGATTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-RsrII |
| ACCN | NM_000508 |
| Insert Size | 2601 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000508.4 |
| RefSeq Size | 3692 bp |
| RefSeq ORF | 2601 bp |
| Locus ID | 2243 |
| UniProt ID | P02671 |
| Domains | FBG |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
| MW | 95 kDa |
| Gene Summary | This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (alpha-E) represents the longer transcript and encodes the longer isoform (alpha-E). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224278 | FGA (Myc-DDK-tagged)-Human fibrinogen alpha chain (FGA), transcript variant alpha-E |
CNY 6,344.00 |
|
| RC224278L3 | Lenti ORF clone of Human fibrinogen alpha chain (FGA), transcript variant alpha-E, Myc-DDK-tagged |
CNY 11,120.00 |
|
| RC224278L4 | Lenti ORF clone of Human fibrinogen alpha chain (FGA), transcript variant alpha-E, mGFP tagged |
CNY 11,120.00 |
|
| RG224278 | FGA (tGFP-tagged) - Human fibrinogen alpha chain (FGA), transcript variant alpha-E |
CNY 10,170.00 |
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