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PDZD6 (INTU) (NM_015693) Human Untagged Clone
CAT＃: SC314961
INTU (untagged)-Human inturned planar cell polarity effector homolog (Drosophila) (INTU)
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CPLANE4; INT; OFD17; PDZD6; PDZK6; SRTD20 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC314961 representing NM_015693.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCCTCTGTGGCTTCGTGCGATTCGCGTCCGAGCTCAGACGAGCTCCCTGGAGACCCCTCTTCACAA GAAGAAGATGAGGACTATGATTTTGAAGATCGGGTCAGCGACTCGGGTTCATATTCCTCAGCGAGTAGC GATTATGATGATCTTGAGCCTGAATGGCTGGACAGTGTGCAGAAAAATGGAGAGCTGTTTTATTTGGAA TTGAGTGAGGATGAAGAAGAAAGCCTCCTTCCTGAGACACCAACTGTGAACCATGTCAGGTTCAGTGAA AATGAGATTATCATTGAAGATGACTACAAAGAAAGAAAAAAGTATGAACCCAAACTCAAGCAGTTTACC AAAATTTTAAGAAGGAAAAGACTTTTACCCAAGCGCTGCAATAAAAAAAATAGCAATGACAATGGACCA GTATCCATTCTAAAGCATCAGTCCAATCAGAAGACAGGAGTCATTGTCCAACAGCGATACAAAGATGTG AATGTTTATGTAAACCCCAAAAAGCTAACTGTTATCAAAGCCAAAGAGCAGCTCAAGCTTCTGGAAGTG CTGGTTGGAATTATTCATCAGACCAAGTGGAGCTGGAGAAGAACCGGAAAGCAGGGTGATGGAGAGAGG CTTGTGGTTCATGGCCTGCTGCCAGGGGGATCTGCTATGAAGAGCGGTCAGGTACTCATTGGTGATGTC CTTGTTGCTGTGAATGATGTCGATGTTACTACTGAAAACATCGAGAGAGTTCTGTCTTGCATTCCTGGA CCTATGCAGGTGAAACTGACATTTGAAAATGCATATGATGTGAAAAGGGAGACGTCCCATCCAAGACAG AAAAAGACACAGTCCAACACAAGTGATTTAGTCAAGCTTCTCTGGGGAGAAGAGGTTGAAGGTATCCAG CAGAGTGGCCTAAACACTCCTCATATCATTATGTATCTCACACTACAGCTCGACTCAGAAACCTCAAAG GAAGAGCAGGAAATTCTTTATCATTATCCAATGTCTGAAGCATCTCAGAAACTTAAAAGTGTGAGAGGG ATTTTTCTCACACTCTGTGACATGCTGGAAAACGTAACTGGGACACAAGTTACTAGTTCATCCCTCCTT TTAAATGGAAAACAAATTCATGTGGCTTATTGGAAAGAATCTGACAAGTTGTTGCTAATTGGCCTGCCT GCTGAAGAAGTTCCTCTTCCTCGTCTAAGGAACATGATAGAAAATGTCATCCAAACCTTAAAATTTATG TATGGTTCTTTAGATAGTGCCTTTTGCCAGATTGAGAATGTTCCTCGTTTGGATCATTTTTTTAACTTG TTCTTTCAAAGAGCACTTCAGCCTGCGAAACTGCATTCCAGCGCCAGTCCCAGTGCTCAGCAGTACGAT GCTTCCAGTGCAGTACTTTTAGACAACCTCCCTGGAGTCCGGTGGCTCACACTTCCACTGGAAATCAAG ATGGAATTAGACATGGCATTAAGTGACTTGGAGGCTGCAGATTTTGCAGAACTGTCCGAGGATTACTAT GACATGAGGCGGCTGTATACAATTTTGGGGTCTTCTCTATTTTACAAGGGTTATTTGATATGCAGTCAT TTGCCCAAGGATGATCTTATTGATATTGCCGTATACTGTCGCCACTATTGCCTGCTGCCTTTAGCAGCA AAACAAAGAATTGGTCAGTTGATCATATGGAGAGAAGTGTTTCCTCAGCATCACCTCCGACCTTTGGCA GACTCAAGCACTGAAGTCTTTCCGGAACCTGAAGGAAGATATTTTTTGCTAGTTGTTGGCTTGAAACAT TATATGCTATGTGTACTATTAGAAGCTGGAGGTTGCGCATCCAAAGCTATTGGGAGTCCTGGACCAGAC TGTGTATATGTGGATCAAGTCAAAACAACTCTTCACCAGCTGGATGGAGTAGATTCTCGCATAGATGAA CGGCTAGCATCTTCTCCAGTCCCCTGTTTGTCTTGTGCTGACTGGTTCCTTACTGGATCACGTGAAAAA ACAGATAGCTTGACCACTTCGCCTATTCTCAGTAGGCTACAAGGTACTTCCAAAGTAGCAACTTCTCCA ACATGCAGAAGAACGCTTTTTGGTGACTATTCCTTAAAGACACGCAAGCCTAGTCCTTCCTGTAGTAGT GGAGGATCTGACAATGGTTGTGAAGGTGGAGAAGATGATGGCTTTAGCCCCCATACTACACCGGATGCA GTACGGAAGCAAAGAGAATCTCAGGGCTCTGATGGTTTAGAAGAAAGTGGGACCTTGCTTAAGGTCACT AAAAAGAAGTCTACTCTTCCAAATCCATTTCATTTGGGAAACTTGAAAAAGGACCTTCCAGAAAAAGAA TTAGAAATATATAACACAGTGAAACTGACATCTGGTCCTGAGAACACACTTTTCCACTACGTTGCCTTA GAAACAGTGCAAGGAATCTTTATTACTCCTACCCTTGAAGAGGTGGCACAGCTAAGTGGCTCTATCCAC CCTCAGCTAATAAAGAATTTCCATCAGTGTTGTCTTTCCATTCGTGCAGTTTTCCAACAGACATTGGTG GAAGAGAAAAAGAAAGGACTAAATAGTGGAGACCATTCAGATTCTGCAAAGTCAGTGTCTTCTCTTAAC CCTGTTAAAGAACATGGTGTGTTGTTTGAATGTTCACCTGGAAACTGGACTGATCAGAAAAAAGCACCA CCAGTTATGGCTTACTGGGTAGTAGGGAGACTTTTTCTTCATCCAAAACCTCAAGAACTTTATGTCTGT TTTCATGACTCAGTCACAGAAATTGCCATTGAAATAGCTTTTAAATTGTTCTTTGGGTTAACCTTGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_015693 |
| Insert Size | 2829 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015693.3 |
| RefSeq Size | 3275 bp |
| RefSeq ORF | 2829 bp |
| Locus ID | 27152 |
| UniProt ID | Q9ULD6 |
| MW | 105.6 kDa |
| Gene Summary | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218556 | INTU (Myc-DDK-tagged)-Human inturned planar cell polarity effector homolog (Drosophila) (INTU) |
CNY 6,896.00 |
|
| RC218556L1 | Lenti ORF clone of Human inturned planar cell polarity effector homolog (Drosophila) (INTU), Myc-DDK-tagged |
CNY 9,296.00 |
|
| RC218556L2 | Lenti ORF clone of Human inturned planar cell polarity effector homolog (Drosophila) (INTU), mGFP tagged |
CNY 9,030.00 |
|
| RC218556L3 | Lenti ORF clone of Human inturned planar cell polarity effector homolog (Drosophila) (INTU), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC218556L4 | Lenti ORF clone of Human inturned planar cell polarity effector homolog (Drosophila) (INTU), mGFP tagged |
CNY 9,030.00 |
|
| RG218556 | INTU (tGFP-tagged) - Human inturned planar cell polarity effector homolog (Drosophila) (INTU) |
CNY 8,496.00 |
