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Polycystin 2 (PKD2) (NM_000297) Human Untagged Clone
CAT＃: SC315012
PKD2 (untagged)-Human polycystic kidney disease 2 (autosomal dominant) (PKD2)
CNY 10,640.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APKD2; Pc-2; PC2; PKD4; TRPP2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000297 edited
GCGCCGGGAAGAAAGGAACATGGCTCCTGAGGCGCACAGCGCCGAGCGCGGCGCCGCGCA CCCGCGCGCCGGACGCCAGTGACCGCGATGGTGAACTCCAGTCGCGTGCAGCCTCAGCAG CCCGGGGACGCCAAGCGGCCGCCCGCGCCCCGCGCGCCGGACCCGGGCCGGCTGATGGCT GGCTGCGCGGCCGTGGGCGCCAGCCTCGCCGCCCCGGGCGGCCTCTGCGAGCAGCGGGGC CTGGAGATCGAGATGCAGCGCATCCGGCAGGCGGCCGCGCGGGACCCCCCGGCCGGAGCC GCGGCCTCCCCTTCTCCTCCGCTCTCGTCGTGCTCCCGGCAGGCGTGGAGCCGCGATAAC CCCGGCTTCGAGGCCGAGGAGGAGGAGGAGGAGGTGGAAGGGGAAGAAGGCGGAATGGTG GTGGAGATGGACGTAGAGTGGCGCCCGGGCAGCCGGAGGTCGGCCGCCTCCTCGGCCGTG AGCTCCGTGGGCGCGCGGAGCCGGGGGCTTGGGGGCTACCACGGCGCGGGCCACCCGAGC GGGAGGCGGCGCCGGCGAGAGGACCAGGGCCCGCCGTGCCCCAGCCCAGTCGGCGGCGGG GACCCGCTGCATCGCCACCTCCCCCTGGAAGGGCAGCCGCCCCGAGTGGCCTGGGCGGAG AGGCTGGTTCGCGGGCTGCGAGGTCTCTGGGGAACAAGACTCATGGAGGAAAGCAGCACT AACCGAGAGAAATACCTTAAAAGTGTTTTACGGGAACTGGTCACATACCTCCTTTTTCTC ATAGTCTTGTGCATCTTGACCTACGGCATGATGAGCTCCAATGTGTACTACTACACCCGG ATGATGTCACAGCTCTTCCTAGACACCCCCGTGTCCAAAACGGAGAAAACTAACTTTAAA ACTCTGTCTTCCATGGAAGACTTCTGGAAGTTCACAGAAGGCTCCTTATTGGATGGGCTG TACTGGAAGATGCAGCCCAGCAACCAGACTGAAGCTGACAACCGAAGTTTCATCTTCTAT GAGAACCTGCTGTTAGGGGTTCCACGAATACGGCAACTCCGAGTCAGAAATGGATCCTGC TCTATCCCCCAGGACTTGAGAGATGAAATTAAAGAGTGCTATGATGTCTACTCTGTCAGT AGTGAAGATAGGGCTCCCTTTGGGCCCCGAAATGGAACCGCTTGGATCTACACAAGTGAA AAAGACTTGAATGGTAGTAGCCACTGGGGAATCATTGCAACTTATAGTGGAGCTGGCTAT TATCTGGATTTGTCAAGAACAAGAGAGGAAACAGCTGCACAAGTTGCTAGCCTCAAGAAA AATGTCTGGCTGGACCGAGGAACCAGGGCAACTTTTATTGACTTCTCAGTGTACAACGCC AACATTAACCTGTTCTGTGTGGTCAGGTTATTGGTTGAATTCCCAGCAACAGGTGGTGTG ATTCCATCTTGGCAATTTCAGCCTTTAAAGCTGATCCGATATGTCACAACTTTTGATTTC TTCCTGGCAGCCTGTGAGATTATCTTTTGTTTCTTTATCTTTTACTATGTGGTGGAAGAG ATATTGGAAATTCGCATTCACAAACTACACTATTTCAGGAGTTTCTGGAATTGTCTGGAT GTTGTGATCGTTGTGCTGTCAGTGGTAGCTATAGGAATTAACATATACAGAACATCAAAT GTGGAGGTGCTACTACAGTTTCTGGAAGATCAAAATACTTTCCCCAACTTTGAGCATCTG GCATATTGGCAGATACAGTTCAACAATATAGCTGCTGTCACAGTATTTTTTGTCTGGATT AAGCTCTTCAAATTCATCAATTTTAACAGGACCATGAGCCAGCTCTCGACAACCATGTCT CGATGTGCCAAAGACCTGTTTGGCTTTGCTATTATGTTCTTCATTATTTTCCTAGCGTAT GCTCAGTTGGCATACCTTGTCTTTGGCACTCAGGTCGATGACTTCAGTACTTTCCAAGAG TGTATCTTCACTCAATTCCGTATCATTTTGGGCGATATCAACTTTGCAGAGATTGAGGAA GCTAATCGAGTTTTGGGACCAATTTATTTCACTACATTTGTGTTCTTTATGTTCTTCATT CTTTTGAATATGTTTTTGGCTATCATCAATGATACTTACTCTGAAGTGAAATCTGACTTG GCACAGCAGAAAGCTGAAATGGAACTCTCAGATCTTATCAGAAAGGGCTACCATAAAGCT TTGGTCAAACTAAAACTGAAAAAAAATACCGTGGATGACATTTCAGAGAGTCTGCGGCAA GGAGGAGGCAAGTTAAACTTTGACGAACTTCGACAAGATCTCAAAGGGAAGGGCCATACT GATGCAGAGATTGAGGCAATATTCACAAAGTACGACCAAGATGGAGACCAAGAACTGACC GAACATGAACATCAGCAGATGAGAGACGACTTGGAGAAAGAGAGGGAGGACCTGGATTTG GATCACAGTTCTTTACCACGTCCCATGAGCAGCCGAAGTTTCCCTCGAAGCCTGGATGAC TCTGAGGAGGATGACGATGAAGATAGCGGACATAGCTCCAGAAGGAGGGGAAGCATTTCT AGTGGCGTTTCTTACGAAGAGTTTCAAGTCCTGGTGAGACGAGTGGACCGGATGGAGCAT TCCATCGGCAGCATAGTGTCCAAGATTGACGCCGTGATCGTGAAGCTAGAGATTATGGAG CGAGCCAAACTGAAGAGGAGGGAGGTGCTGGGAAGGCTGTTGGATGGGGTGGCCGAGGAT GAAAGGCTGGGTCGTGACAGTGAAATCCATAGGGAACAGATGGAACGGCTAGTACGTGAA GAGTTGGAACGCTGGGAATCCGATGATGCAGCTTCCCAGATCAGTCATGGTTTAGGCACG CCAGTGGGACTAAATGGTCAACCTCGCCCCAGAAGCTCCCGCCCATCTTCCTCCCAATCT ACAGAAGGCATGGAAGGTGCAGGTGGAAATGGGAGTTCTAATGTCCACGTATGATATGTG TGTTTCAGTATGTGTGTTTCTAATAAGTGAGGAAGTGGCTGTCCTGAATTGCTG |
| Restriction Sites | Please inquire |
| ACCN | NM_000297 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_000297.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000297.2, NP_000288.1 |
| RefSeq Size | 5073 bp |
| RefSeq ORF | 2907 bp |
| Locus ID | 5311 |
| UniProt ID | Q13563 |
| Domains | ion_trans |
| Protein Families | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane |
| Gene Summary | This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011] Transcript Variant: This variant (1) represents the longer transcript. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220948 | PKD2 (Myc-DDK-tagged)-Human polycystic kidney disease 2 (autosomal dominant) (PKD2) |
CNY 7,088.00 |
|
| RC220948L1 | Lenti-ORF clone of PKD2 (Myc-DDK-tagged)-Human polycystic kidney disease 2 (autosomal dominant) (PKD2) |
CNY 5,890.00 |
|
| RC220948L2 | Lenti-ORF clone of PKD2 (mGFP-tagged)-Human polycystic kidney disease 2 (autosomal dominant) (PKD2) |
CNY 9,488.00 |
|
| RC220948L3 | Lenti-ORF clone of PKD2 (Myc-DDK-tagged)-Human polycystic kidney disease 2 (autosomal dominant) (PKD2) |
CNY 9,488.00 |
|
| RC220948L4 | Lenti-ORF clone of PKD2 (mGFP-tagged)-Human polycystic kidney disease 2 (autosomal dominant) (PKD2) |
CNY 9,488.00 |
|
| RG220948 | PKD2 (tGFP-tagged) - Human polycystic kidney disease 2 (autosomal dominant) (PKD2) |
CNY 8,688.00 |
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