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KIDINS220 (AL133620) Human Untagged Clone
CNY 27,270.00
货期*
7周
规格
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经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARMS |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for AL133620, the custom clone sequence may differ by one or more nucleotides
ATGTCAGTTTTGATATCACAGAGCGTCATAAATTATGTAGAGGAAGAAAACATTCCTGCT CTGAAAGCTCTTCTTGAAAAATGCAAAGATGTAGATGAGAGAAATGAGTGTGGCCAGACT CCACTGATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGAAT GGAGCTAACTGCAATCTGGAAGATTTGGATAATTGGACAGCACTTATATCTGCATCGAAA GAAGGGCATGTGCACATCGTAGAGGAACTACTGAAATGTGGGGTTAACTTGGAGCACCGT GATATGGGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAGTA GAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTCACTGGTCTGCAGTACAGTGTTTAC CCAATCATTTGGGCAGCAGGGAGAGGCCATGCAGATATAGTTCATCTTTTACTGCAAAAT GGTGCTAAAGTCAACTGCTCTGATAAGTATGGAACCACCCCTTTAGTTTGGGCTGCACGA AAGGGTCATTTGGAATGTGTGAAACATTTATTGGCCATGGGAGCTGATGTGGATCAAGAA GGAGCTAATTCAATGACTGCACTTATTGTGGCAGTGAAAGGAGGTTACACACAGTCAGTA AAAGAAATTTTGAAGAGGAATCCAAATGTAAACTTAACAGATAAAGATGGAAATACAGCT TTGATGATTGCATCAAAGGAGGGACATACGGAGATTGTGCAGGATCTGCTCGACGCTGGA ACATATGTGAACATACCTGACAGGAGTGGGGATACTGTGTTGATTGGCGCTGTCAGAGGT GGTCATGTTGAAATTGTTCGAGCGCTTCTCCAAAAATATGCTGATATAGACATTAGAGGA CAGGATAATAAAACTGCTTTGTATTGGGCTGTTGAGAAAGGAAATGCAACAATGGTGAGA GATATCTTACAGTGCAATCCTGACACTGAAATATGCACAAAGGATGGTGAAACGCCACTT ATAAAGGCTACCAAGATGAGAAACATTGAAGTGGTGGAGCTGCTGCTAGATAAAGGTGCT AAAGTGTCTGCTGTAGATAAGAAAGGAGATACTCCCTTGCATATTGCTATTCGTGGAAGG AGCCGGAAACTGGCAGAACTGCTTTTAAGAAATCCCAAAGATGGGCGATTACTTTATAGG CCCAACAAAGCAGGCGAGACTCCTTATAATATTGACTGTAGCCATCAGAAGAGTATTTTA ACTCAAATATTTGGAGCCAGACACTTGTCTCCTACTGAAACAGACGGTGACATGCTTGGA TATGATTTATATAGCAGTGCCCTGGCAGATATTCTCAGTGAGCCTACCATGCAGCCACCC ATTTGTGTGGGGTTATATGCACAGTGGGGAAGTGGGAAATCTTTCTTACTCAAGAAACTA GAAGACGAAATGAAAACCTTCGCCGGACAACAGATTGAGCCTCTCTTTCAGTTCTCATGG CTCATAGTGTTTCTTACCCTGCTACTTTGTGGAGGGCTTGGTTTATTGTTTGCCTTCACG GTCCACCCAAATCTTGGAATAGCAGTGTCACTGAGCTTCTTGGCTCTCTTATATATATTC TTTATTGTCATTTACTTTGGTGGACGAAGAGAAGGAGAGAGTTGGAATTGGGCCTGGGTC CTCAGCACTAGATTGGCAAGACATATTGGATATTTGGAACTCCTCCTTAAATTGATGTTT GTGAATCCACCTGAGTTGCCAGAGCAGACTACTAAAGCTTTACCTGTGAGGTTTTTGTTT ACAGATTACAATAGACTGTCCAGTGTAGGTGGAGAAACTTCTCTGGCTGAAATGATTGCA ACCCTCTCGGATGCTTGTGAAAGAGAGTTTGGCTTTTTGGCAACCAGGCTTTTTCGAGTA TTCAAGACTGAAGATACTCAGGGTAAAAAGAAATGGAAAAAAACATGTTGTCTCCCATCT TTTGTCATCTTCCTTTTTATCATTGGCTGCATTATATCTGGAATTACTCTTCTGGCTATA TTTAGAGTTGACCCAAAGCATCTGACTGTAAATGCTGTCCTCATATCAATCGCATCTGTA GTGGGATTGGCCTTTGTGTTGAACTGTCGTACATGGTGGCAAGTGCTGGACTCGCTCCTG AATTCCCAAAGAAAACGCCTCCATAATGCAGCCTCCAAACTGCACAAATTGAAAAGTGAA GGATTCATGAAAGTTCTTAAATGTGAAGTGGAATTGATGGCCAGGATGGCAAAAACCATT GACAGCTTCACTCAGAATCAGACAAGGCTGGTGGTCATCATCGATGGATTAGATGCCTGT GAGCAGGACAAAGTCCTTCAGATGCTGGACACTGTCCGAGTTCTGTTTTCAAAAGGCCCG TTCATTGCCATTTTTGCAAGTGATCCACATATTATCATAAAGGCAATTAACCAGAACCTC AATAGTGTGCTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCAC TTGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCAAGAAAATTTCTCGTAACTTCA GCAACAAATGGAGACGTTCCATGCTCAGATACTACAGGGATACAGGAAGATGCTGACAGA AGAGTTTCACAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAAT AGACGGGACACTTACCGAAGAAGGCAGATGCAGAGGACCATCACTCGCCAGATGTCCTTT GATCTTACAAAACTGCTGGTTACCGAGGACTGGTTCAGTGACATCAGTCCCCAGACCATG AGAAGATTACTTAATATTGTTTCTGTGACAGGACGATTACTGAGAGCCAATCAGATTAGT TTCAACTGGGACAGGCTTGCTAGCTGGATCAACCTTACTGAGCAGTGGCCATACCGGACT TCATGGCTCATATTATATTTGGAAGAGACTGAAGGTATTCCAGATCAAATGACATTAAAA ACCATCTACGAAAGATGCTGTGGAGCAGACAGTTGTGACCGAGACCGAATTGGCATTTCC AAGTCAGTGTTAGTTGCCATGTTGATGGAGAGC |
| Restriction Sites | Please inquire |
| ACCN | AL133620 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | AL133620.1, CAB63746.1 |
| RefSeq Size | 3789 bp |
| RefSeq ORF | 3789 bp |
| Locus ID | 57498 |
| Domains | ANK |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Neurotrophin signaling pathway |
| Gene Summary | This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] |
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