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Liprin alpha 1 (PPFIA1) (NM_177423) Human Untagged Clone
CAT＃: SC315247
PPFIA1 (untagged)-Human protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 (PPFIA1), transcript variant 1
CNY 22,710.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LIP.1; LIP1; LIPRIN |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC315247 representing NM_177423.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGT TCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAA AGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACAC GAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGAGTTCGCAGCA CTTACTAAAGAACTCAATGTATGCAGGGAACAGCTCCTTGAAAGGGAAGAAGAAATTGCTGAACTGAAA GCAGAAAGGAATAACACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCT CTTAGGATGACCGTGGTGAAGAGACAAGCGCAGTCTCCAGCAGGCGTGTCCAGCGAAGTGGAAGTGCTG AAAGCACTGAAGTCCTTATTTGAACACCACAAAGCTCTGGATGAAAAGGTGAGAGAGCGATTACGAGTA GCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCACACACAAAGAGCTAATGATTCTTAAA GAACAGAATAATCAGAAAAAAACTCTAACAGATGGAGTGCTGGACATAAACCATGAACAAGAAAATACA CCAAGCACGAGTGGAAAGAGATCTTCTGATGGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATT GAGCTCCAAGAAATCATAAGTAAGCAGTCAAGGGAACAGAGCCAAATGAAAGAACGCCTGGCTTCCCTT TCCAGTCATGTGACAGAACTGGAAGAGGATCTGGACACGGCTAGAAAAGATCTCATCAAATCTGAAGAA ATGAACACAAAATTGCAACGAGATGTCCGTGAAGCCATGGCCCAAAAGGAAGATATGGAAGAGAGAATC ACTACTCTTGAAAAACGCTACCTCGCTGCACAGCGTGAAGCCACATCTGTGCATGACCTCAATGATAAA CTTGAAAATGAAATTGCAAATAAAGATTCTATGCATCGACAGACTGAAGATAAAAACCGCCAGTTACAG GAGCGCTTGGAATTGGCAGAGCAAAAGCTGCAACAGACACTGAGGAAGGCAGAGACGCTCCCGGAGGTG GAGGCGGAGCTGGCCCAGAGGGTGGCAGCGCTTTCCAAGGCTGAAGAGAGACACGGCAACATTGAAGAA AGGTTACGACAGATGGAAGCACAGTTGGAGGAGAAGAATCAAGAACTGCAGCGGGCAAGGCAAAGAGAA AAAATGAACGAAGAACATAATAAACGTTTATCAGACACTGTTGACAAGCTGCTTTCAGAATCTAATGAG AGGCTTCAACTTCATCTTAAAGAGAGAATGGCTGCTTTGGAAGATAAGAACTCTCTTTTAAGAGAAGTT GAAAGTGCAAAAAAGCAGTTAGAAGAAACACAACACGATAAGGATCAGCTTGTCCTAAACATTGAAGCA CTGAGGGCTGAACTAGACCACATGAGACTAAGAGGTGCTTCACTTCATCATGGCCGACCCCACTTGGGC AGTGTCCCAGATTTCAGGTTCCCCATGGCAGACGGCCACACAGACTCCTACAGCACCAGTGCAGTGCTG CGGCGCCCACAGAAAGGCCGGCTGGCAGCCCTGCGAGATGAGCCTTCCAAGGTACAAACTCTTAATGAG CAGGATTGGGAACGTGCCCAGCAAGCTAGTGTCTTGGCAAATGTAGCACAAGCATTCGAGAGTGATGCT GACGTGTCTGATGGTGAAGATGACAGGGACACTCTCCTCAGCTCAGTTGACCTGCTATCGCCCAGCGGG CAGGCCGACGCGCACACACTAGCCATGATGCTTCAGGAGCAGCTGGACGCCATCAACAAAGAGATCAGG TTGATTCAGGAAGAAAAAGAAAATACAGAGCAGCGGGCAGAGGAGATTGAAAGTCGAGTTGGCAGTGGA AGTCTAGACAATCTTGGTCGTTTTAGATCAATGAGCTCCATTCCCCCCTACCCTGCTTCCTCGCTTGCT AGCTCCTCCCCTCCGGGCAGTGGGCGCTCCACCCCACGAAGGATCCCTCACAGCCCAGCTCGGGAAGTG GACAGACTGGGCGTCATGACCCTTTTGCCACCTTCCAGAGAAGAGGTACGAGATGACAAGACAACCATA AAGTGTGAAACCTCCCCGCCTTCCTCCCCGAGAGCCCTTCGGTTAGACCGGCTGCACAAAGGGGCGCTG CACACCGTCAGCCACGAGGACATCAGGGACATAAGGAACTCCACAGGCTCCCAGGATGGTCCCGTGAGC AACCCCAGCAGTAGCAACAGTAGCCAGGACTCGCTCCACAAAGCCCCAAAGAAGAAAGGCATTAAGTCC TCCATTGGCCGCTTGTTTGGCAAGAAAGAAAAGGGCCGACCTGGACAAACTGGCAAAGAAGCATTAGGA CAAGCTGGTGTTTCCGAGACGGATAACTCATCTCAGGATGCCTTGGGACTTAGCAAATTGGGGGGACAG GCTGAAAAAAATCGTAAACTTCAAAAAAAGCATGAATTGCTGGAGGAAGCCCGGAGACAAGGTTTACCT TTTGCCCAATGGGACGGGCCAACGGTTGTGGTCTGGCTAGAGCTCTGGGTTGGGATGCCAGCCTGGTAT GTGGCTGCCTGCCGAGCAAACGTGAAAAGCGGGGCCATCATGTCGGCCCTGTCCGACACAGAGATCCAG CGTGAGATTGGCATCAGCAACCCCCTGCACAGGCTGAAGCTGAGGCTGGCCATCCAGGAGATCATGTCG CTGACCAGCCCGTCTGCCCCGCCCACATCTAGAACGACACTCGCCTATGGGGACATGAACCACGAGTGG ATCGGCAACGAGTGGCTCCCCAGCCTGGGCCTCCCCCAGTACCGCAGCTACTTCATGGAGTGCCTTGTA GACGCCAGGATGCTGGACCACTTGACCAAGAAAGACCTTCGAGGGCAGCTGAAAATGGTCGACAGTTTT CACAGAAACAGTTTCCAGTGTGGAATTATGTGCCTGAGAAGGTTAAATTATGACCGGAAAGAACTGGAA AGAAAAAGAGAAGAAAGTCAGAGTGAAATAAAAGACGTGCTTGTTTGGAGCAATGATCGAGTGATTCGC TGGATCCTGTCAATTGGCCTTAAAGAATATGCAAACAATCTTATAGAGAGTGGTGTTCACGGAGCACTT CTGGCCTTAGATGAAACCTTCGACTTCAGTGCACTGGCACTGCTGTTACAGATCCCGACGCAGAACACA CAGGCTCGTGCTGTCTTGGAAAGAGAATTTAACAACCTTTTGGTCATGGGGACTGATAGAAGGTTTGAT GAAGATGATGATAAAAGCTTTAGGAGAGCACCTTCATGGAGAAAAAAGTTTAGACCAAAGGACATTCGT GGCTTAGCTGCTGGGTCAGCAGAGACTCTCCCTGCAAACTTCCGGGTGACTTCTTCTATGTCTTCCCCC TCTATGCAGCCAAAGAAGATGCAGATGGACGGTATGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_177423 |
| Insert Size | 3558 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_177423.2 |
| RefSeq Size | 4062 bp |
| RefSeq ORF | 3558 bp |
| Locus ID | 8500 |
| UniProt ID | Q13136 |
| Protein Families | Druggable Genome, Phosphatase |
| MW | 134 kDa |
| Gene Summary | The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) differs in the 3' end, which includes a part of the coding region and 3' UTR, as compared to variant 2. The resulting protein (isoform a) has a distinct and shorter C-terminus, as compared to isoform b. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212893 | PPFIA1 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 (PPFIA1), transcript variant 1 |
CNY 8,248.00 |
|
| RC212893L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 (PPFIA1), transcript variant 1, Myc-DDK-tagged |
CNY 13,680.00 |
|
| RC212893L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 (PPFIA1), transcript variant 1, mGFP tagged |
CNY 13,680.00 |
|
| RG212893 | PPFIA1 (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 (PPFIA1), transcript variant 1 |
CNY 12,920.00 |
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