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Bax inhibitor 1 (TMBIM6) (NM_001098576) Human Untagged Clone
CAT＃: SC316357
TMBIM6 (untagged)-Human transmembrane BAX inhibitor motif containing 6 (TMBIM6), transcript variant 2
CNY 6,270.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BAXI1; BI-1; TEGT |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC316357 representing NM_001098576.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTCACACTCCTCTGTGACACGCGAGGCTCCTCAGTTACTTAGCCAACGGCAGAGGCGGGAAGTGAGA GGAGTCTGGGGCTGGGGCTGCCTTCCAGGCCCACGGGGCGGCCCCGCTCTTTTCGGATTGGTTACCTTT GGGCAGAGTGGAGACTGCTGCACGGACTCTGGAACCATGAACATATTTGATCGAAAGATCAACTTTGAT GCGCTTTTAAAATTTTCTCATATAACCCCGTCAACGCAGCAGCACCTGAAGAAGGTCTATGCAAGTTTT GCCCTTTGTATGTTTGTGGCGGCTGCAGGGGCCTATGTCCATATGGTCACTCATTTCATTCAGGCTGGC CTGCTGTCTGCCTTGGGCTCCCTGATATTGATGATTTGGCTGATGGCAACACCTCATAGCCATGAAACT GAACAGAAAAGACTGGGACTTCTTGCTGGATTTGCATTCCTTACAGGAGTTGGCCTGGGCCCTGCCCTG GAGTTTTGTATTGCTGTCAACCCCAGCATCCTTCCCACTGCTTTCATGGGCACGGCAATGATCTTTACC TGCTTCACCCTCAGTGCACTCTATGCCAGGCGCCGTAGCTACCTCTTTCTGGGAGGTATCTTGATGTCA GCCCTGAGCTTGTTGCTTTTGTCTTCCCTGGGGAATGTTTTCTTTGGATCCATTTGGCTTTTCCAGGCA AACCTGTATGTGGGACTGGTGGTCATGTGTGGCTTCGTCCTTTTTGATACTCAACTCATTATTGAAAAG GCCGAACATGGAGATCAAGATTATATCTGGCACTGCATTGATCTCTTCTTAGATTTCATTACTGTCTTC AGAAAACTCATGATGATCCTGGCCATGAATGAAAAGGATAAGAAGAAAGAGAAGAAATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001098576 |
| Insert Size | 888 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001098576.1 |
| RefSeq Size | 3255 bp |
| RefSeq ORF | 888 bp |
| Locus ID | 7009 |
| UniProt ID | P55061 |
| Protein Families | Druggable Genome, Transmembrane |
| MW | 32.7 kDa |
| Gene Summary | Suppressor of apoptosis (PubMed:21075086). Modulates unfolded protein response signaling (PubMed:21075086). Modulates ER calcium homeostasis by acting as a calcium-leak channel (PubMed:22128171). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses a different segment for the 5' UTR and 5' coding region, compared to variant 1. The resulting protein (isoform 2) is longer and has a distinct N-terminus when it is compared to isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219708 | TMBIM6 (Myc-DDK-tagged)-Human transmembrane BAX inhibitor motif containing 6 (TMBIM6), transcript variant 2 |
CNY 2,400.00 |
|
| RC219708L3 | Lenti ORF clone of Human transmembrane BAX inhibitor motif containing 6 (TMBIM6), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC219708L4 | Lenti ORF clone of Human transmembrane BAX inhibitor motif containing 6 (TMBIM6), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG219708 | TMBIM6 (tGFP-tagged) - Human transmembrane BAX inhibitor motif containing 6 (TMBIM6), transcript variant 2 |
CNY 4,000.00 |
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