Histone acetyltransferase MYST3 (KAT6A) (NM_001099413) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	MOZ; MRD32; MYST3; RUNXBP2; ZC2HC6A; ZNF220
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >SC316615 representing NM_001099413. Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTTTGGAGGCCATCAAAAAAGTGAAAAAGCAG AAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGATCGTAAAACT GTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAAT TCCTATAAAGATCCTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGAT AATAAACAAAATGTGGATTGGAATAAACTGATAAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGC TCAACTTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCATTATTCGGAGGCAGT GCTGCCTCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTT AAAGATGGACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCT CTTTCCTGTTTACCTCCAGTGTCCCTTCTTCCACATGAAAAGGATAAGCCGGTTGCTGAACCAATCCCC ATCTGTAGTTTCTGTCTTGGTACAAAAGAACAAAACCGAGAAAAGAAGCCAGAGGAACTCATCTCCTGT GCCGACTGTGGCAACAGTGGCCATCCATCCTGTTTAAAGTTTTCCCCTGAACTAACGGTTCGAGTGAAG GCCTTACGGTGGCAGTGCATCGAGTGTAAAACATGCAGCTCCTGTCGAGATCAAGGCAAAAATGCGGAT AACATGCTCTTTTGTGATTCATGTGACCGAGGTTTTCACATGGAGTGTTGTGATCCGCCACTCACCCGT ATGCCAAAAGGCATGTGGATATGTCAAATATGTCGACCTAGGAAAAAAGGACGAAAACTTCTACAAAAG AAGGCAGCACAGATAAAACGGCGCTATACTAATCCAATAGGACGTCCAAAAAACAGGTTAAAGAAACAA AACACGGTATCAAAAGGTCCCTTCAGCAAAGTTCGAACTGGCCCTGGAAGGGGTAGGAAACGAAAAATC ACTCTTTCCAGCCAATCAGCATCATCATCATCAGAAGAAGGATATTTAGAGCGGATAGATGGCTTGGAC TTCTGCAGAGATAGCAATGTCTCCTTGAAGTTCAACAAGAAAACCAAAGGGCTCATTGATGGCCTTACC AAATTTTTTACCCCTTCCCCTGATGGGCGGAAAGCTCGGGGGGAAGTGGTGGACTACTCTGAGCAATAT CGAATCAGAAAGAGGGGCAACAGGAAATCAAGCACTTCAGATTGGCCCACAGACAATCAGGATGGCTGG GATGGCAAACAAGAAAATGAGGAGCGACTTTTTGGGAGCCAGGAAATCATGACTGAGAAAGATATGGAA TTATTTCGTGATATCCAAGAACAAGCACTGCAGAAAGTTGGAGTGACTGGTCCCCCTGATCCACAAGTC CGCTGTCCCTCTGTCATTGAGTTTGGGAAGTATGAAATTCACACCTGGTACTCCTCCCCATATCCTCAA GAATACTCAAGGCTGCCCAAATTGTATCTTTGTGAATTTTGTCTAAAATATATGAAAAGTAGAACTATT CTGCAGCAGCACATGAAGAAATGTGGTTGGTTCCATCCTCCTGCCAATGAGATTTACAGAAAGAATAAT ATTTCTGTCTTTGAGGTTGATGGGAATGTGAGTACCATTTATTGTCAAAACCTGTGTCTTTTGGCAAAG TTGTTTCTTGACCACAAAACCCTCTATTACGATGTGGAGCCATTTCTTTTTTATGTACTAACACAGAAT GATGTCAAGGGCTGCCACCTTGTTGGCTACTTTTCTAAGGAAAAGCACTGCCAACAGAAGTACAATGTT TCCTGTATAATGATTCTTCCTCAATACCAGCGTAAGGGCTATGGCAGGTTTCTCATCGATTTCAGTTAT TTGTTATCAAAGCGTGAAGGCCAAGCAGGGTCTCCAGAGAAACCGTTATCTGATCTGGGTCGTCTTTCC TACATGGCATATTGGAAAAGTGTAATATTGGAGTGCCTTTATCACCAAAATGACAAGCAGATCAGCATT AAGAAGTTAAGCAAGTTGACTGGAATCTGCCCTCAAGACATCACTTCCACACTCCACCACCTACGAATG CTGGACTTCCGTAGTGACCAATTTGTGATTATCCGCCGGGAAAAACTTATCCAGGATCACATGGCAAAG CTTCAGCTGAATTTGCGACCTGTAGATGTAGATCCAGAATGTTTGCGCTGGACTCCAGTCATAGTGTCC AACTCTGTGGTCTCAGAGGAGGAAGAAGAGGAGGCTGAGGAAGGAGAAAACGAAGAGCCACAGTGCCAG GAAAGAGAATTAGAGATCAGTGTGGGAAAGTCTGTGTCTCATGAGAACAAAGAACAAGATTCTTATTCA GTAGAAAGTGAAAAGAAACCAGAAGTTATGGCTCCAGTCAGTTCTACACGTTTGAGCAAACAAGTCCTT CCTCATGATAGTCTTCCTGCAAATAGCCAGCCATCTCGGAGGGGCCGCTGGGGGAGGAAGAACAGAAAA ACCCAGGAACGTTTTGGTGATAAAGATTCTAAACTGCTCTTGGAAGAGACGTCTTCAGCTCCTCAGGAA CAATATGGAGAATGTGGGGAGAAATCAGAAGCCACCCAGGAACAATACACTGAAAGTGAAGAACAGCTG GTGGCTTCTGAGGAGCAGCCAAGCCAGGACGGGAAACCTGACCTTCCCAAGAGAAGACTCAGTGAGGGG GTTGAGCCCTGGCGAGGACAGCTCAAGAAAAGCCCTGAGGCTCTGAAGTGCAGATTAACAGAAGGAAGT GAGAGGCTGCCCCGTCGCTACAGTGAGGGTGACAGGGCTGTCCTCAGGGGCTTCAGTGAGAGCAGCGAG GAGGAGGAGGAGCCGGAAAGCCCTCGGTCAAGCTCGCCACCAATTCTCACAAAGCCCACGCTGAAGCGA AAGAAACCATTTCTCCACCGAAGGAGGAGAGTCCGAAAGCGCAAACACCACAATAGCAGTGTAGTCACA GAAACTATTTCTGAGACCACTGAAGTGTTAGATGAACCTTTTGAAGATTCTGACTCCGAGAGGCCAATG CCAAGATTAGAACCCACGTTTGAGATCGATGAAGAAGAGGAGGAAGAGGATGAAAATGAACTTTTCCCT AGAGAATACTTCCGTCGTTTGTCTTCGCAGGATGTACTCAGGTGTCAGTCCTCTTCTAAGAGGAAGTCT AAAGATGAAGAAGAAGATGAAGAGTCAGATGATGCTGATGACACTCCTATCTTAAAGCCAGTATCTCTT TTGCGAAAACGTGATGTGAAGAATTCTCCTCTTGAGCCAGATACATCCACACCTTTGAAAAAGAAAAAG GGATGGCCCAAAGGCAAGAGCCGCAAACCAATCCACTGGAAGAAAAGACCTGGTCGAAAACCAGGATTT AAGTTGAGTCGGGAAATCATGCCAGTTTCTACTCAAGCATGCGTCATTGAGCCCATCGTTTCCATTCCT AAAGCTGGACGTAAACCCAAGATCCAGGAGAGTGAAGAAACTGTTGAGCCAAAAGAAGACATGCCCCTA CCCGAGGAGAGGAAGGAGGAGGAGGAGATGCAAGCAGAGGCAGAAGAGGCTGAAGAGGGTGAGGAAGAG GATGCAGCCAGCAGTGAAGTCCCAGCAGCCTCTCCAGCAGACAGCAGCAATAGTCCTGAGACCGAAACC AAGGAGCCTGAGGTGGAGGAGGAAGAAGAGAAGCCCCGTGTCTCAGAGGAGCAGAGGCAGTCAGAGGAG GAGCAGCAGGAATTAGAGGAGCCAGAGCCAGAGGAGGAGGAAGATGCAGCTGCAGAGACTGCCCAGAAT GACGACCACGACGCTGATGATGAGGATGATGGCCACCTGGAGTCCACAAAGAAAAAGGAGCTAGAGGAA CAGCCCACGAGGGAAGATGTCAAGGAGGAGCCTGGTGTTCAAGAGTCTTTTTTAGATGCTAATATGCAG AAGAGTAGGGAAAAGATAAAGGATAAAGAGGAAACCGAGCTGGATTCCGAAGAGGAGCAGCCTTCCCAT GACACGTCCGTGGTGTCAGAGCAGATGGCTGGGTCTGAGGACGACCACGAAGAAGACTCCCACACTAAG GAAGAGTTAATCGAATTAAAAGAGGAGGAAGAGATTCCTCATAGTGAGCTGGATCTGGAAACTGTACAG GCAGTGCAGTCTTTGACTCAAGAAGAAAGCAGTGAGCATGAGGGCGCCTACCAGGACTGTGAGGAAACT CTTGCGGCGTGTCAGACCCTGCAGAGTTACACCCAGGCTGACGAGGACCCTCAGATGTCCATGGTTGAA GACTGTCATGCGTCAGAACATAATAGCCCTATCTCCTCCGTTCAGTCTCACCCCAGCCAGTCAGTCCGT TCGGTCAGCAGTCCCAACGTGCCTGCCCTTGAGAGTGGCTACACCCAGATCAGCCCAGAACAAGGATCC CTGTCCGCACCCTCTATGCAGAACATGGAGACCAGCCCCATGATGGATGTGCCTTCCGTATCAGACCAC TCTCAGCAGGTGGTGGACAGCGGCTTCAGTGACCTGGGCAGCATTGAGAGCACCACTGAAAACTATGAG AACCCAAGCAGTTACGACTCCACGATGGGCGGCAGCATCTGTGGGAACAGCTCTTCCCAGAGCAGCTGC TCCTACGGTGGGCTGTCGTCCTCCAGCAGCCTCACCCAGAGCAGCTGTGTGGTCACTCAGCAGATGGCC AGCATGGGCAGCAGCTGCAGCATGATGCAGCAGAGCAGCGTCCAGCCTGCTGCCAACTGCAGCATCAAG TCACCTCAGAGCTGCGTGGTGGAGAGGCCTCCCAGTAACCAGCAGCAGCAGCCGCCACCACCGCCTCCA CAGCAGCCACAGCCGCCGCCGCCACAACCACAACCAGCACCACAGCCTCCACCACCCCAGCAGCAGCCG CAACAGCAGCCGCAGCCTCAGCCCCAGCAGCCTCCACCCCCACCCCCTCCCCAGCAGCAGCCCCCGCTG TCACAGTGTAGTATGAATAACAGTTTCACCCCAGCTCCTATGATCATGGAGATACCAGAATCTGGAAGC ACTGGGAACATAAGTATCTATGAGAGGATTCCAGGGGATTTTGGTGCCGGCAGCTACTCTCAACCATCA GCCACCTTCAGCCTAGCCAAGCTGCAGCAGCTGACCAACACCATTATGGACCCTCATGCCATGCCTTAT AGCCATTCTCCTGCTGTGACTTCCTATGCAACCAGTGTTTCTCTGTCCAATACAGGACTGGCTCAGCTG GCTCCATCTCATCCCTTAGCTGGGACTCCTCAAGCACAAGCCACCATGACGCCACCCCCAAACTTGGCA TCCACTACCATGAACCTCACATCTCCTCTGCTTCAGTGCAACATGTCTGCCACCAACATTGGCATTCCT CACACGCAGAGATTGCAAGGGCAAATGCCAGTGAAGGGGCACATTTCCATCCGCTCCAAGTCTGCGCCA CTGCCCTCTGCGGCTGCTCACCAGCAGCAGCTGTATGGCCGTAGCCCATCGGCAGTTGCCATGCAGGCT GGCCCTCGCGCACTGGCTGTTCAGCGTGGCATGAACATGGGGGTTAATCTGATGCCTACTCCCGCCTAT AATGTCAATTCCATGAATATGAACACCTTGAATGCCATGAACAGCTATCGAATGACACAGCCCATGATG AACAGCAGTTACCATAGTAACCCTGCCTACATGAACCAGACAGCACAGTATCCTATGCAGATGCAGATG GGAATGATGGGGAGCCAGGCCTATACCCAGCAGCCTATGCAGCCTAACCCTCATGGGAACATGATGTAC ACAGGCCCCTCCCATCACAGCTACATGAACGCTGCTGGCGTGCCCAAGCAGTCACTCAACGGACCTTAC ATGAGAAGATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
Restriction Sites	SgfI-MluI
ACCN	NM_001099413
Insert Size	6015 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001099413.1
RefSeq Size	9241 bp
RefSeq ORF	6015 bp
Locus ID	7994
Protein Families	Druggable Genome, Transcription Factors
MW	225 kDa
Gene Summary	This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same protein.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.