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RPTP mu (PTPRM) (NM_001105244) Human Untagged Clone
CAT＃: SC317168
PTPRM (untagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1
CNY 10,032.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | hR-PTPu; PTPRL1; R-PTP-MU; RPTPM; RPTPU |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001105244 edited
ATGAGGGGACTTGGGACTTGCCTGGCGACTTTGGCCGGACTTTTGCTAACTGCGGCGGGC GAGACGTTCTCAGGTGGCTGCCTCTTTGATGAGCCGTATAGCACATGTGGATATAGTCAA TCTGAAGGTGATGACTTCAATTGGGAGCAAGTGAACACCTTGACTAAACCGACTTCTGAT CCATGGATGCCATCAGGTTCTTTCATGCTGGTGAATGCCTCTGGGAGACCTGAGGGGCAG AGAGCCCACCTGCTCTTACCCCAACTTAAAGAAAATGACACCCACTGCATCGATTTTCAC TATTTTGTGTCCAGCAAGAGTAATTCTCCTCCGGGGTTACTCAATGTCTACGTGAAGGTC AATAACGGGCCACTGGGGAATCCTATCTGGAATATATCTGGAGACCCAACACGTACATGG AACAGGGCAGAACTGGCCATTAGTACTTTCTGGCCTAACTTTTATCAGGTGATTTTTGAA GTGATAACTTCTGGACATCAAGGCTATCTCGCTATCGATGAGGTGAAGGTGTTAGGACAT CCATGTACCAGGACTCCTCACTTCCTGCGGATTCAGAATGTGGAAGTTAATGCTGGCCAG TTTGCTACCTTCCAGTGCAGTGCCATCGGCAGGACCGTGGCAGGAGACAGGCTCTGGTTA CAGGGCATTGATGTGCGAGATGCTCCTCTGAAGGAAATCAAGGTGACCAGCTCCCGACGC TTCATTGCTTCATTTAATGTTGTGAATACCACCAAACGAGATGCTGGAAAGTACCGCTGC ATGATTCGCACTGAAGGAGGTGTTGGAATATCAAACTATGCAGAGTTGGTAGTTAAAGAA CCACCCGTTCCTATTGCCCCACCTCAGCTCGCCTCTGTAGGAGCCACCTACCTGTGGATA CAGCTCAACGCCAACTCCATCAATGGGGATGGGCCCATTGTGGCCCGAGAGGTGGAGTAC TGCACGGCCAGTGGGAGCTGGAATGACCGGCAGCCAGTCGATTCCACGAGCTATAAAATT GGACACCTTGACCCAGATACAGAATATGAGATTAGTGTGCTCCTGACCAGGCCAGGGGAG GGTGGCACTGGCTCTCCTGGTCCAGCTCTCAGGACAAGAACAAAGTGTGCTGATCCCATG CGAGGCCCAAGAAAACTAGAAGTAGTGGAGGTCAAATCTCGGCAAATCACTATCCGCTGG GAGCCATTTGGATATAATGTAACTCGTTGCCACAGTTATAATCTCACTGTCCACTACTGT TACCAAGTTGGAGGACAAGAACAAGTGCGAGAAGAAGTAAGCTGGGATACAGAAAACTCA CACCCTCAACACACGATCACTAACCTGTCACCATACACCAATGTCAGTGTGAAACTGATC CTCATGAACCCAGAGGGCCGGAAGGAAAGCCAAGAACTCATAGTGCAGACAGATGAAGAC CTCCCAGGTGCTGTTCCCACTGAATCCATACAAGGAAGTACCTTTGAAGAGAAGATATTT CTTCAGTGGAGAGAACCAACTCAAACATATGGTGTAATCACTTTATATGAGATCACCTAC AAAGCAGTCAGTTCCTTTGACCCAGAAATAGATTTATCCAATCAGAGTGGAAGAGTTTCA AAGCTGGGAAATGAAACCCATTTTCTGTTTTTTGGACTGTATCCGGGGACCACATACTCC TTTACCATCCGAGCTAGCACAGCTAAGGGTTTTGGGCCTCCAGCAACAAACCAGTTCACC ACCAAAATATCAGCACCCTCTATGCCAGCTTATGAACTTGAGACACCTTTGAATCAAACT GACAATACCGTGACAGTCATGCTGAAACCTGCCCACAGCAGAGGAGCACCTGTCAGTGTC TATCAAATAGTTGTTGAGGAAGAACGTCCTCGAAGAACTAAAAAGACGACAGAAATCTTA AAGTGCTACCCAGTGCCAATTCACTTCCAGAATGCTTCTCTGCTGAACTCACAGTACTAC TTTGCTGCAGAATTTCCTGCAGACAGCCTCCAAGCTGCGCAGCCTTTTACAATTGGTGAT AATAAGACATATAATGGATACTGGAACACTCCCCTTCTCCCCTATAAAAGCTACAGAATT TATTTCCAAGCTGCTAGTAGAGCCAATGGGGAAACCAAAATAGACTGTGTCCAAGTGGCC ACAAAAGGAGCTGCCACTCCGAAACCAGTCCCAGAACCCGAGAAACAGACAGACCATACA GTTAAAATTGCTGGAGTCATCGCGGGCATCTTGCTGTTCGTGATTATATTTCTTGGAGTT GTGTTGGTAATGAAGAAAAGGAAACTGGCCAAGAAGCGGAAAGAGACCATGAGCAGCACC CGACAGGAGATGACTGTGATGGTGAACTCAATGGACAAGAGCTATGCTGAGCAGGGCACA AACTGCGACGAGGCTTTCTCATTCATGGACACGCACAATCTGAATGGGAGATCTGTGTCT TCACCATCGTCCTTCACAATGAAAACAAATACACTGAGCACATCGGTGCCTAATTCCTAT TACCCAGACCCATTTGTGCCAACTGCAATTTTAGTGCCAATAAATGATGAAACCCACACA ATGGCCAGCGATACCAGCAGCCTGGTGCAGTCCCATACTTACAAGAAGCGAGAGCCGGCC GACGTGCCCTATCAGACTGGGCAGCTCCACCCCGCCATCCGGGTGGCAGACCTCCTTCAG CACATCACACAGATGAAGTGTGCGGAGGGCTACGGCTTCAAGGAGGAATACGAGAGCTTC TTTGAAGGGCAGTCTGCACCATGGGACTCGGCTAAGAAAGATGAGAACAGAATGAAGAAC AGATACGGGAATATCATTGCATACGATCATTCCCGAGTGAGGCTGCAGACAATAGAAGGA GACACAAACTCAGACTATATCAATGGCAATTATATCGATGGTTATCATCGACCCAATCAT TACATTGCTACCCAAGGGCCAATGCAGGAAACCATCTATGACTTCTGGAGGATGGTGTGG CACGAAAACACTGCAAGTATCATCATGGTGACCAATCTTGTGGAAGTGGGAAGGGTCAAA TGCTGCAAATACTGGCCAGATGACACAGAGATATATAAAGACATTAAAGTTACCCTAATA GAAACAGAACTACTGGCAGAATATGTGATAAGAACATTTGCTGTTGAAAAGAGAGGTGTG CATGAAATCCGAGAGATCAGACAGTTTCACTTCACTGGCTGGCCGGATCATGGGGTCCCC TACCATGCCACCGGCCTGCTGGGATTCGTGCGGCAAGTCAAGTCCAAGAGCCCGCCCAGT GCAGGCCCACTGGTGGTGCACTGCAGTGCTGGTGCAGGGAGGACTGGCTGTTTCATCGTC ATTGATATCATGTTGGACATGGCCGAAAGGGAAGGGGTCGTAGACATCTACAACTGCGTC AGGGAGCTGCGGTCACGGAGGGTGAACATGGTGCAAACAGAGGAGCAGTATGTGTTTATC CACGATGCGATCCTGGAAGCCTGTCTTTGTGGGGACACCTCTGTGCCTGCTTCCCAAGTT AGGTCTCTGTATTATGACATGAACAAACTGGATCCACAGACAAACTCAAGCCAGATTAAA GAGGAATTCCGGACGCTAAACATGGTGACACCAACGCTGCGAGTAGAGGACTGCAGCATC GCACTGTTGCCCCGGAACCATGAGAAAAACCGGTGCATGGACATCCTGCCCCCAGACCGC TGCCTGCCCTTCCTCATCACCATCGATGGGGAGAGCAGCAACTACATCAATGCTGCCCTC ATGGACAGCTATAAACAGCCTTCAGCTTTTATAGTCACCCAGCATCCTTTGCCAAACACA GTGAAAGACTTTTGGAGACTGGTCCTGGATTATCACTGCACATCCGTAGTTATGCTAAAT GATGTGGATCCTGCCCAGTTGTGTCCACAGTACTGGCCAGAAAACGGAGTACACAGACAC GGCCCCATCCAGGTGGAATTTGTCTCTGCTGACCTGGAAGAGGACATCATCAGCAGGATA TTCCGCATTTACAATGCCGCCAGACCCCAAGATGGATATCGGATGGTGCAGCAATTCCAG TTCCTGGGCTGGCCGATGTACAGGGACACACCAGTGTCTAAGCGCTCCTTCTTGAAGCTC ATTCGCCAGGTGGACAAGTGGCAAGAGGAGTACAATGGCGGGGAAGGCCGCACGGTTGTG CACTGCTTGAACGGGGGAGGCCGCAGTGGGACGTTCTGCGCCATCAGCATCGTATGTGAG ATGCTCCGGCACCAGAGAACCGTGGATGTCTTTCACGCTGTGAAGACACTGAGGAACAAC AAGCCCAACATGGTCGACCTCCTGGATCAGTACAAGTTCTGCTACGAGGTGGCCCTGGAA TACTTGAATTCTGGCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_001105244 |
| Insert Size | 4400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001105244.1, NP_001098714.1 |
| RefSeq Size | 5624 bp |
| RefSeq ORF | 4398 bp |
| Locus ID | 5797 |
| UniProt ID | P28827 |
| Protein Families | Druggable Genome, Phosphatase, Transmembrane |
| Protein Pathways | Adherens junction, Cell adhesion molecules (CAMs) |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226398 | PTPRM (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1 |
CNY 10,024.00 |
|
| RC226398L3 | Lenti-ORF clone of PTPRM (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1 |
CNY 16,530.00 |
|
| RC226398L4 | Lenti-ORF clone of PTPRM (mGFP-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1 |
CNY 16,530.00 |
|
| RG226398 | PTPRM (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1 |
CNY 11,624.00 |
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