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HEXO (ERI1) (NM_153332) Human Untagged Clone
CAT＃: SC317546
ERI1 (untagged)-Human exoribonuclease 1 (ERI1)
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 3'HEXO; HEXO; THEX1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC317546 representing NM_153332.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAGGATCCACAGAGTAAAGAGCCTGCCGGCGAGGCCGTGGCTCTCGCGCTGCTGGAGTCGCCGCGG CCGGAGGGCGGGGAGGAGCCGCCGCGTCCCAGTCCCGAGGAAACTCAACAGTGTAAATTTGATGGCCAG GAGACAAAAGGATCCAAGTTCATTACCTCCAGTGCGAGTGACTTCAGTGACCCGGTTTACAAAGAGATT GCCATTACGAATGGCTGTATTAATAGAATGAGTAAGGAAGAACTCAGAGCTAAGCTTTCAGAATTCAAG CTTGAAACTAGAGGAGTAAAGGATGTTCTAAAGAAGAGACTGAAAAACTATTATAAGAAGCAGAAGCTG ATGCTGAAAGAGAGCAATTTTGCTGACAGTTATTATGACTACATTTGTATTATTGACTTTGAAGCCACT TGTGAAGAAGGAAACCCACCTGAGTTTGTACATGAAATAATTGAATTTCCGGTTGTTTTACTGAATACG CATACTTTAGAAATAGAAGACACGTTTCAGCAGTATGTAAGACCAGAGATTAACACACAGCTGTCTGAT TTCTGCATCAGTCTAACTGGAATTACTCAGGATCAGGTAGACAGAGCTGATACCTTCCCTCAGGTACTA AAAAAAGTAATTGACTGGATGAAATTGAAGGAATTAGGAACAAAGTATAAATACTCACTTTTAACAGAT GGTTCTTGGGATATGAGTAAGTTCTTGAACATTCAGTGTCAACTCAGCAGGCTCAAATACCCTCCTTTT GCGAAAAAGTGGATCAATATTCGGAAGTCATATGGAAATTTTTACAAGGTTCCTAGAAGCCAAACCAAA CTGACAATAATGCTTGAAAAATTAGGAATGGATTATGATGGGCGGCCTCACTGTGGTCTTGATGACTCT AAGAATATCGCCCGAATAGCAGTTCGAATGCTTCAGGATGGGTGTGAACTCCGAATCAACGAGAAAATG CATGCAGGACAGCTAATGAGTGTGTCCTCTTCCTTACCAATAGAGGGCACTCCACCACCACAAATGCCA CATTTTAGAAAGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_153332 |
| Insert Size | 1050 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_153332.3 |
| RefSeq Size | 4615 bp |
| RefSeq ORF | 1050 bp |
| Locus ID | 90459 |
| UniProt ID | Q8IV48 |
| MW | 40.1 kDa |
| Gene Summary | RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206777 | ERI1 (Myc-DDK-tagged)-Human exoribonuclease 1 (ERI1) |
CNY 5,488.00 |
|
| RC206777L1 | Lenti ORF clone of Human exoribonuclease 1 (ERI1), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC206777L2 | Lenti ORF clone of Human exoribonuclease 1 (ERI1), mGFP tagged |
CNY 5,890.00 |
|
| RC206777L3 | Lenti ORF clone of Human exoribonuclease 1 (ERI1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206777L4 | Lenti ORF clone of Human exoribonuclease 1 (ERI1), mGFP tagged |
CNY 5,890.00 |
|
| RG206777 | ERI1 (tGFP-tagged) - Human exoribonuclease 1 (ERI1) |
CNY 7,088.00 |
|
| SC321806 | ERI1 (untagged)-Human exoribonuclease 1 (ERI1) |
CNY 3,656.00 |
