Karyopherin beta 3 (IPO5) (NM_002271) Human Untagged Clone
CAT#: SC318500
IPO5 (untagged)-Human importin 5 (IPO5)
CNY 10,450.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | IMB3; imp5; KPNB3; Pse1; RANBP5 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_002271, the custom clone sequence may differ by one or more nucleotides
ATGCCTGAGGATCAAGTTGGAAAACTAGAAGCAACAGAAAACACAATAAGCGCAATGGCG GCGGCCGCGGCGGAGCAGCAACAGTTCTACCTGCTCCTGGGAAACCTGCTCAGCCCCGAC AATGTGGTCCGGAAACAGGCAGAGGAAACCTATGAGAATATCCCAGGCCAGTCAAAGATC ACATTCCTCTTACAAGCCATCAGAAATACAACAGCTGCTGAAGAGGCTAGACAAATGGCC GCCGTTCTCCTAAGACGTCTCTTGTCCTCTGCATTTGATGAAGTCTATCCAGCACTTCCC TCTGATGTTCAGACTGCCATCAAGAGTGAGCTACTCATGATTATTCAGATGGAAACACAA TCTAGCATGAGGAAAAAAGTTTGTGATATTGCGGCAGAACTGGCCAGGAATTTAATAGAT GAGGATGGCAATAACCAGTGGCCCGAAGGTTTGAAGTTCCTTTTTGATTCAGTCAGCTCT CAAAATGTGGGACTGCGGGAAGCTGCCCTTCACATTTTCTGGAACTTTCCTGGAATTTTT GGGAACCAGCAACAACACTATTTAGATGTCATCAAACGAATGTTAGTTCAGTGTATGCAA GATCAGGAACACCCGTCGATCAGGACGTTATCTGCTAGAGCTACAGCTGCATTTATACTT GCAAATGAGCATAATGTTGCTCTGTTCAAACATTTTGCAGACTTGCTACCGGGATTCCTA CAGGCGGTAAATGACTCGTGCTACCAGAATGATGATTCTGTCCTAAAATCCCTCGTTGAG ATTGCAGATACTGTTCCAAAGTATTTGCGTCCTCACTTGGAAGCAACTCTACAGCTAAGT CTAAAGTTGTGTGGAGACACTAGCCTCAACAATATGCAACGCCAGCTTGCCCTTGAAGTG ATCGTCACCCTCTCTGAGACTGCAGCTGCTATGTTAAGAAAACATACCAATATTGTTGCA CAGACTATTCCTCAGATGTTAGCAATGATGGTTGATTTGGAAGAAGATGAGGACTGGGCA AATGCAGATGAACTAGAAGATGATGATTTTGACAGCAATGCAGTTGCAGGCGAGAGTGCT CTAGATCGAATGGCTTGCGGACTTGGTGGAAAGCTCGTTCTGCCGATGATCAAGGAACAC ATTATGCAAATGCTTCAAAATCCTGACTGGAAATACCGGCATGCAGGATTGATGGCCTTA TCTGCCATTGGTGAAGGGTGCCACCAGCAAATGGAAGGAATTCTAAATGAGATCGTAAAT TTTGTTTTACTTTTTCTCCAGGATCCTCATCCAAGAGTAAGGTATGCAGCCTGTAATGCC GTGGGACAGATGGCTACAGATTTTGCACCTGGTTTCCAAAAGAAATTTCATGAGAAGGTG ATTGCAGCTCTGCTGCAGACCATGGAAGACCAAGGCAATCAACGTGTGCAGGCCCATGCA GCTGCTGCCCTCATTAACTTTACTGAAGACTGTCCCAAGTCACTACTTATTCCATACTTG GATAATTTGGTGAAACATCTGCATTCCATTATGGTACTGAAGCTTCAAGAGCTGATTCAG AAAGGCACCAAGTTAGTTTTGGAACAAGTTGTGACATCCATTGCATCAGTTGCCGATACT GCAGAAGAAAAATTTGTCCCCTACTATGATTTATTTATGCCATCACTGAAGCACATCGTT GAGAATGCGGTTCAAAAAGAACTGAGACTTCTGAGAGGAAAAACTATTGAATGCATTAGC CTCATTGGTCTGGCTGTTGGGAAGGAAAAATTCATGCAGGATGCATCAGATGTGATGCAG CTTTTGTTAAAGACCCAGACAGACTTCAATGATATGGAAGATGATGATCCTCAGATCTCT TACATGATCTCAGCATGGGCCAGAATGTGCAAAATCCTTGGAAAAGAATTTCAGCAATAC CTTCCAGTGGTTATGGGGCCTTTAATGAAGACGGCTTCAATTAAGCCCGAAGTAGCCCTT TTAGATACCCAAGACATGGAGAATATGAGTGATGATGATGGTTGGGAATTTGTGAACCTT GGAGATCAGCAAAGCTTTGGTATTAAAACTGCAGGACTAGAAGAAAAATCAACTGCTTGC CAGATGTTGGTTTGCTATGCTAAGGAGTTAAAGGAAGGCTTTGTGGAGTACACCGAACAG GTTGTCAAACTGATGGTCCCTTTACTGAAATTTTATTTCCACGATGGTGTTCGAGTGGCA GCAGCGGAATCCATGCCTCTTCTCCTGGAGTGTGCAAGAGTCCGTGGTCCTGAGTATCTC ACACAGATGTGGCATTTTATGTGTGATGCTCTAATTAAGGCCATTGGTACAGAACCAGAT TCAGACGTCCTCTCAGAAATAATGCATTCTTTTGCAAAGTGCATTGAAGTAATGGGAGAT GGATGCCTTAATAATGAACACTTTGAAGAACTGGGAGGTATATTGAAAGCAAAGCTTGAA GAACATTTTAAAAATCAAGAATTACGACAAGTTAAAAGACAAGATGAAGACTATGATGAA CAGGTCGAAGAGTCACTACAAGATGAGGATGATAATGATGTTTATATTCTGACCAAAGTG TCAGATATTTTACACTCAATATTCAGTAGCTACAAAGAAAAGGTGTTACCATGGTTTGAA CAGCTGCTTCCATTAATTGTCAACCTCATTTGTCCACATAGACCATGGCCAGACAGACAA TGGGGATTATGCATCTTTGATGATGTCATAGAACACTGTAGTCCAGCCTCATTTAAATAC GCAGAATATTTCTTAAGACCAATGCTCCAATATGTATGTGACAACAGCCCAGAAGTCAGG CAAGCAGCTGCATATGGCCTGGGAGTCATGGCACAGTACGGTGGAGATAATTATCGCCCT TTTTGTACAGAAGCACTTCCCCTGCTGGTAAGAGTTATTCAGTCTGCGGATTCTAAGACC AAAGAAAATGTCAATGCTACAGAGAACTGCATCTCAGCAGTAGGGAAAATCATGAAGTTC AAGCCTGACTGTGTAAACGTTGAAGAGGTCCTTCCACACTGGTTGTCTTGGCTTCCACTA CATGAAGATAAAGAAGAAGCTGTTCAGACTTTCAATTATCTGTGTGACCTGATTGAAAGT AATCATCCAATTGTTCTTGGCCCAAACAATACCAATCTGCCCAAAATATTTAGTATAATT GCGGAAGGAGAAATGCACGAGGCAATTAAACATGAAGATCCTTGTGCCAAACGTCTGGCC AATGTCGTTCGCCAAGTACAGACTTCTGGAGGACTGTGGACTGAGTGCATAGCACAGCTC AGTCCTGAGCAGCAGGCCGCCATTCAGGAGCTCCTGAACTCTGCG |
Restriction Sites | Please inquire |
ACCN | NM_002271 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_002271.4, NP_002262.3 |
RefSeq Size | 6019 bp |
RefSeq ORF | 3348 bp |
Locus ID | 3843 |
UniProt ID | O00410 |
Protein Families | Druggable Genome |
Gene Summary | Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC207221 | IPO5 (Myc-DDK-tagged)-Human importin 5 (IPO5) |
CNY 7,768.00 |
|
RC207221L1 | Lenti-ORF clone of IPO5 (Myc-DDK-tagged)-Human importin 5 (IPO5) |
CNY 10,168.00 |
|
RC207221L2 | Lenti-ORF clone of IPO5 (mGFP-tagged)-Human importin 5 (IPO5) |
CNY 13,020.00 |
|
RC207221L3 | Lenti-ORF clone of IPO5 (Myc-DDK-tagged)-Human importin 5 (IPO5) |
CNY 13,020.00 |
|
RC207221L4 | Lenti-ORF clone of IPO5 (mGFP-tagged)-Human importin 5 (IPO5) |
CNY 13,020.00 |
|
RG207221 | IPO5 (tGFP-tagged) - Human importin 5 (IPO5) |
CNY 12,260.00 |
|
SC118726 | IPO5 (untagged)-Human importin 5 (IPO5) |
CNY 7,648.00 |
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