AP3D1 (NM_003938) Human Untagged Clone

CAT#: SC318527

AP3D1 (untagged)-Human adaptor-related protein complex 3, delta 1 subunit (AP3D1), transcript variant 2



  "NM_003938" in other vectors (4)

CNY 22,230.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


Goat polyclonal anti-AP3D1 antibody
    • 100 ug

CNY 8,025.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ADTD; hBLVR; HPS10
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>SC318527 representing NM_003938.
Blue=Insert sequence Red=Cloning site Green=Tag(s)

GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
ATGGCCCTCAAGATGGTGAAGGGCAGCATCGACCGCATGTTCGACAAGAATCTGCAGGACTTGGTCCGC
GGCATCCGTAACCACAAGGAGGACGAGGCAAAATACATATCTCAGTGCATTGATGAGATCAAGCAGGAG
CTGAAGCAGGACAACATAGCGGTGAAGGCGAACGCGGTCTGCAAGCTGACGTATTTACAGATGTTGGGA
TACGACATCAGCTGGGCCGCCTTCAACATCATAGAAGTGATGAGTGCCTCCAAGTTCACCTTCAAGCGA
ATTGGCTACCTCGCTGCTTCCCAGAGCTTTCACGAAGGCACCGACGTCATCATGCTGACCACCAATCAG
ATCCGTAAGGACTTGAGCAGCCCCAGCCAGTACGACACAGGTGTTGCACTGACGGGTCTGTCCTGCTTC
GTCACCCCAGACCTTGCCAGAGACCTGGCAAATGACATCATGACACTGATGTCACACACCAAGCCCTAC
ATCAGGAAGAAGGCTGTGCTGATCATGTACAAGGTGTTCCTGAAGTACCCCGAGTCGCTGCGCCCTGCC
TTTCCCCGGCTGAAGGAGAAGCTGGAGGACCCCGACCCCGGGGTTCAGTCGGCTGCCGTCAATGTCATC
TGCGAGCTGGCCAGACGCAACCCTAAGAACTACCTGTCCCTGGCCCCGCTCTTTTTCAAGCTGATGACG
TCCTCCACCAACAACTGGGTCCTCATCAAGATCATCAAGCTGTTCGGTGCTCTTACTCCTTTGGAACCG
CGGCTGGGCAAGAAGCTGATCGAGCCCCTCACCAATCTCATCCACAGCACGTCTGCCATGTCTCTCCTC
TATGAATGTGTGAACACCGTGATTGCAGTGCTCATCTCGCTGTCCTCCGGCATGCCCAACCACAGCGCC
AGCATCCAGCTTTGTGTTCAGAAATTAAGGATATTGATCGAGGACTCCGATCAGAACTTGAAGTACCTG
GGGCTGCTGGCAATGTCCAAGATCCTGAAGACCCACCCCAAGTCCGTGCAGTCCCACAAGGACCTCATC
CTGCAGTGCCTGGACGACAAGGACGAGTCCATCCGGCTGCGGGCCCTGGACCTGCTCTATGGGATGGTG
TCCAAGAAGAACCTGATGGAGATCGTGAAGAAGCTGATGACCCACGTAGACAAGGCAGAGGGTACCACC
TACCGTGACGAGCTGCTCACCAAGATCATTGACATCTGCAGCCAGTCCAACTACCAGTACATCACCAAC
TTCGAGTGGTACATCAGCATCCTGGTGGAGCTGACCCGGCTGGAGGGCACACGGCACGGCCACCTCATC
GCCGCCCAAATGCTGGACGTGGCCATCCGCGTGAAGGCCATCCGCAAGTTCGCCGTGTCCCAGATGTCT
GCGCTGCTTGACAGTGCACACCTGCTGGCCAGCAGCACCCAGCGGAACGGGATCTGTGAGGTGCTGTAC
GCTGCCGCCTGGATCTGCGGGGAGTTCTCAGAGCATCTGCAGGAACCACACCACACTTTGGAGGCCATG
CTGCGGCCCAGAGTCACCACGCTGCCAGGCCACATCCAGGCCGTGTATGTGCAGAACGTGGTCAAGCTC
TACGCCTCCATCCTGCAGCAGAAGGAGCAGGCCGGGGAGGCAGAGGGCGCTCAGGCCGTCACCCAGCTC
ATGGTGGACCGGCTGCCCCAGTTTGTGCAGAGCGCAGACCTGGAGGTGCAGGAGCGGGCGTCCTGCATC
CTGCAGCTGGTCAAGCACATCCAGAAGCTTCAGGCCAAGGACGTGCCTGTGGCAGAGGAGGTCAGCGCT
CTCTTTGCTGGGGAGCTGAACCCAGTGGCCCCCAAGGCCCAGAAGAAGGTTCCAGTCCCCGAAGGCCTG
GACCTGGACGCCTGGATCAATGAGCCACTCTCGGACAGCGAGTCAGAGGACGAGAGGCCCAGGGCCGTC
TTCCACGAGGAGGAGCAGCGGCGTCCCAAGCACCGGCCGTCGGAGGCGGACGAGGAAGAGCTGGCTCGG
CGCCGAGAGGCCCGGAAGCAGGAGCAGGCCAACAACCCCTTCTACATCAAGAGCTCGCCATCGCCACAG
AAGCGGTACCAGGACACCCCGGGCGTGGAGCACATTCCCGTGGTGCAGATTGACCTCTCCGTCCCCTTG
AAGGTTCCAGGGCTGCCTATGTCAGATCAGTATGTGAAGCTGGAGGAGGAGCGGCGGCACCGGCAGAAG
CTGGAGAAGGACAAGAGGAGGAAAAAGAGGAAGGAGAAGGAGAAGAAGGGCAAGCGCCGCCACAGCTCG
CTGCCCACGGAGAGCGACGAGGACATCGCCCCTGCCCAGCAGGTGGACATCGTCACAGAGGAGATGCCT
GAGAATGCTCTGCCCAGCGACGAGGATGACAAAGACCCCAACGACCCCTACAGGGCTCTGGATATTGAC
CTGGATAAGCCCTTAGCCGACAGCGAGAAACTGCCTATTCAGAAACACAGAAACACCGAGACCTCAAAA
TCCCCTGAGAAGGACGTTCCCATGGTAGAAAAGAAGAGCAAGAAACCCAAGAAGAAAGAGAAAAAACAC
AAAGAGAAAGAGAGAGACAAGGAGAAGAAGAAGGAGAAGGAGAAGAAGAAATCTCCCAAGCCTAAGAAG
AAGAAGCACAGGAAGGAGAAGGAGGAGCGGACCAAAGGCAAGAAGAAGTCCAAGAAGCAGCCTCCAGGC
AGCGAGGAGGCAGCGGGGGAGCCGGTGCAGAATGGCGCGCCAGAGGAGGAGCAGCTCCCGCCTGAGTCC
AGCTACTCCCTCCTCGCTGAAAATTCCTATGTTAAAATGACCTGTGACATCCGGGGCAGTCTGCAGGAG
GACAGCCAGGTCACTGTGGCCATCGTGCTGGAGAACAGGAGCAGCAGCATCCTCAAGGGCATGGAGCTC
AGCGTGCTGGACTCACTCAATGCCAGGATGGCCCGGCCGCAGGGCTCCTCCGTCCACGATGGCGTCCCC
GTGCCTTTCCAGCTGCCCCCAGGCGTCTCCAACGAAGCCCAGTATGTGTTCACCATCCAGAGCATCGTC
ATGGCGCAGAAGCTCAAGGGGACCCTGTCCTTCATTGCCAAGAATGACGAGGGTGCGACCCACGAGAAG
CTGGACTTCAGGCTGCACTTCAGCTGCAGCTCCTACTTGATCACCACTCCCTGCTACAGTGACGCCTTT
GCTAAGTTGCTGGAGTCTGGGGACTTGAGCATGAGCTCAATCAAAGTCGATGGCATTCGGATGTCCTTC
CAGAATCTTCTGGCGAAGATCTGTTTTCACCACCATTTTTCCGTTGTGGAGCGAGTGGACTCCTGCGCC
TCCATGTACAGCCGCTCCATCCAGGGCCACCATGTCTGCCTCCTGGTGAAAAAGGGTGAGAACTCTGTC
TCAGTCGACGGGAAGTGCAGTGACTCCACGCTACTGAGCAACTTGTTAGAAGAGATGAAGGCGACGCTG
GCCAAGTGTTGA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
TACAAGGATGACGACGATAAG
GTTTAAACGGCCGGC
Restriction Sites SgfI-MluI     
ACCN NM_003938
Insert Size 3462 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_003938.6
RefSeq Size 4887 bp
RefSeq ORF 3462 bp
Locus ID 8943
UniProt ID O14617
Domains Adaptin_N
Protein Families Druggable Genome
Protein Pathways Lysosome
MW 130.2 kDa
Gene Summary The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome. [provided by RefSeq, Feb 2017]
Transcript Variant: This variant (2) lacks two alternate in-frame exons in the 3' coding region compared to variant 3. The encoded isoform (2) is shorter than isoform 3.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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