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NALP5 (NLRP5) (NM_153447) Human Untagged Clone
CAT＃: SC318548
NLRP5 (untagged)-Human NLR family, pyrin domain containing 5 (NLRP5)
CNY 12,544.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLR19.8; MATER; NALP5; PAN11; PYPAF8 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_153447 edited
ATGAAGGTTGCAGGAGGACTTGAACTTGGAGCTGCTGCTCTGCTCTCAGCATCACCACGT GCTCTTGTCACTCTTTCCACAGGTCCTACTTGCTCTATATTACCAAAGAATCCACTTTTC CCCCAAAACCTGAGCTCTCAGCCTTGTATCAAGATGGAAGGAGACAAATCGCTCACCTTT TCCAGCTACGGGCTGCAATGGTGTCTCTATGAGCTAGACAAGGAAGAATTTCAGACATTC AAGGAATTACTAAAGAAGAAATCTTCAGAATCGACCACATGCTCTATTCCACAGTTTGAA ATCGAGAATGCCAACGTGGAATGTCTGGCACTCCTCTTGCATGAGTATTATGGAGCATCG CTGGCCTGGGCTACGTCCATTAGCATCTTTGAAAACATGAACCTGCGAACCCTCTCGGAG AAGGCACGGGATGACATGAAAAGACATTCACCAGAAGATCCTGAAGCAACGATGACTGAC CAAGGACCAAGCAAGGAAAAAGTGCCAGGAATTTCACAAGCTGTGCAACAAGATAGTGCC ACAGCTGCAGAGACAAAAGAACAAGAAATTTCACAAGCTATGGAACAAGAAGGTGCCACA GCAGCAGAGACAGAAGAACAAGAAATTTCACAAGCTATGGAACAAGAAGGTGCCACAGCA GCAGAGACAGAAGAACAAGGACATGGAGGTGACACATGGGACTACAAGAGTCACGTGATG ACCAAATTCGCTGAGGAGGAGGATGTACGTCGTAGTTTTGAAAACACTGCTGCTGACTGG CCGGAAATGCAAACGTTGGCTGGTGCTTTTGATTCAGACCGGTGGGGCTTCCGGCCTCGC ACGGTGGTTCTGCACGGAAAGTCAGGAATTGGGAAATCGGCTCTAGCCAGAAGGATCGTG CTGTGCTGGGCGCAAGGTGGACTCTACCAGGGAATGTTCTCCTACGTCTTCTTCCTCCCC GTTAGAGAGATGCAGCGGAAGAAGGAGAGCAGTGTCACAGAGTTCATCTCCAGGGAGTGG CCAGACTCCCAGGCTCCGGTGACGGAGATCATGTCCCGACCAGAAAGGCTGTTGTTCATC ATTGACGGTTTCGATGACCTGGGCTCTGTCCTCAACAATGACACAAAGCTCTGCAAAGAC TGGGCTGAGAAGCAGCCTCCGTTCACCCTCATACGCAGTCTGCTGAGGAAGGTCCTGCTC CCTGAGTCCTTCCTGATCGTCACCGTCAGAGACGTGGGCACAGAGAAGCTCAAGTCAGAG GTCGTGTCTCCCCGTTACCTGTTAGTTAGAGGAATCTCCGGGGAACAAAGAATCCACTTG CTCCTTGAGCGCGGGATTGGTGAGCATCAGAAGACACAAGGGTTGCGTGCGATCATGAAC AACCGTGAGCTGCTCGACCAGTGCCAGGTGCCCGCCGTGGGCTCTCTCATCTGCGTGGCC CTGCAGCTGCAGGACGTGGTGGGGGAGAGCGTCGCCCCCTTCAACCAAACGCTCACAGGC CTGCACGCCGCTTTTGTGTTTCATCAGCTCACCCCTCGAGGCGTGGTCCGGCGCTGTCTC AATCTGGAGGAAAGAGTTGTCCTGAAGCGCTTCTGCCGTATGGCTGTGGAGGGAGTGTGG AATAGGAAGTCAGTGTTTGACGGTGACGACCTCATGGTTCAAGGACTCGGGGAGTCTGAG CTCCGTGCTCTGTTTCACATGAACATCCTTCTCCCAGACAGCCACTGTGAGGAGTACTAC ACCTTCTTCCACCTCAGTCTCCAGGACTTCTGTGCCGCCTTGTACTACGTGTTAGAGGGC CTGGAAATCGAGCCAGCTCTCTGCCCTCTGTACGTTGAGAAGACAAAGAGGTCCATGGAG CTTAAACAGGCAGGCTTCCATATCCACTCGCTTTGGATGAAGCGTTTCTTGTTTGGCCTC GTGAGCGAAGACGTAAGGAGGCCACTGGAGGTCCTGCTGGGCTGTCCCGTTCCCCTGGGG GTGAAGCAGAAGCTTCTGCACTGGGTCTCTCTGTTGGGTCAGCAGCCTAATGCCACCACC CCAGGAGACACCCTGGACGCCTTCCACTGTCTTTTCGAGACTCAAGACAAAGAGTTTGTT CGCTTGGCATTAAACAGCTTCCAAGAAGTGTGGCTTCCGATTAACCAGAACCTGGACTTG ATAGCATCTTCCTTCTGCCTCCAGCACTGTCCGTATTTGCGGAAAATTCGGGTGGATGTC AAAGGGATCTTCCCAAGAGATGAGTCCGCTGAGGCATGTCCTGTGGTCCCTCTATGGATG CGGGATAAGACCCTCATTGAGGAGCAGTGGGAAGATTTCTGCTCCATGCTTGGCACCCAC CCACACCTGCGGCAGCTGGACCTGGGCAGCAGCATCCTGACAGAGCGGGCCATGAAGACC CTGTGTGCCAAGCTGAGGCATCCCACCTGCAAGATACAGACCCTGATGTTTAGAAATGCA CAGATTACCCCTGGTGTGCAGCACCTCTGGAGAATCGTCATGGCCAACCGTAACCTAAGA TCCCTCAACTTGGGAGGCACCCACCTGAAGGAAGAGGATGTAAGGATGGCGTGTGAAGCC TTAAAACACCCAAAATGTTTGTTGGAGTCTTTGAGGCTGGATTGCTGTGGATTGACCCAT GCCTGTTACCTGAAGATCTCCCAAATCCTTACGACCTCCCCCAGCCTGAAATCTCTGAGC CTGGCAGGAAACAAGGTGACAGACCAGGGAGTAATGCCTCTCAGTGATGCCTTGAGAGTC TCCCAGTGCGCCCTGCAGAAGCTGATACTGGAGGACTGTGGCATCACAGCCACGGGTTGC CAGAGTCTGGCCTCAGCCCTCGTCAGCAACCGGAGCTTGACACACCTGTGCCTATCCAAC AACAGCCTGGGGAACGAAGGTGTAAATCTACTGTGTCGATCCATGAGGCTTCCCCACTGT AGTCTGCAGAGGCTGATGCTGAATCAGTGCCACCTGGACACGGCTGGCTGTGGTTTTCTT GCACTTGCGCTTATGGGTAACTCATGGCTGACGCACCTGAGCCTTAGCATGAACCCTGTG GAAGACAATGGCGTGAAGCTTCTGTGCGAGGTCATGAGAGAACCATCTTGTCATCTCCAG GACCTGGAGTTGGTAAAGTGTCATCTCACCGCCGCGTGCTGTGAGAGTCTGTCCTGTGTG ATCTCGAGGAGCAGACACCTGAAGAGCCTGGATCTCACGGACAATGCCCTGGGTGACGGT GGGGTTGCTGCGCTGTGCGAGGGACTGAAGCAAAAGAACAGTGTTCTGGCGAGACTCGGG TTGAAGGCATGTGGACTGACTTCTGATTGCTGTGAGGCACTCTCCTTGGCCCTTTCCTGC AACCGGCATCTGACCAGTCTAAACCTGGTGCAGAATAACTTCAGTCCCAAAGGAATGATG AAGCTGTGTTCGGCCTTTGCCTGTCCCACGTCTAACTTACAGATAATTGGGCTGTGGAAA TGGCAGTACCCTGTGCAAATAAGGAAGCTGCTGGAGGAAGTGCAGCTACTCAAGCCCCGA GTCGTAATTGACGGTAGTTGGCATTCTTTTGATGAAGATGACCGGTACTGGTGGAAAAAC TGA |
| Restriction Sites | Please inquire |
| ACCN | NM_153447 |
| Insert Size | 3600 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_153447.4, NP_703148.4 |
| RefSeq Size | 3885 bp |
| RefSeq ORF | 3603 bp |
| Locus ID | 126206 |
| UniProt ID | P59047 |
| Gene Summary | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Autoantibody response against NALP5/MATER in primary ovarian insufficiency and in autoimmune Addison's disease
,Brozzetti, A;Alimohammadi, M;Morelli, S;Minarelli, V;Hallgren, Å;Giordano, R;De Bellis, A;Perniola, R;Kämpe, O;Falorni, A;on behalf of the Italian Addison Network, ;,
J. Clin. Endocrinol. Metab.
,PubMed ID 25734249
[NLRP5]
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Autoimmune Polyendocrine Syndrome Type 1 and NALP5, a Parathyroid Autoantigen
,Mohammad Alimohammadi, Peyman Bjorklund, Asa Hallgren, Nora Pontynen, Gabor Szinnai, Noriko Shikama, Marcel P. Keller, Olov Ekwall, Sarah A. Kinkel, Eystein S. Husebye, Jan Gustafsson, Fredrik Rorsman, Leena Peltonen, Corrado Betterle, Jaakko Perheentupa, Goran Akerstrom, Gunnar Westin, Hamish S. Scott, Georg A. Hollander, and Olle Kampe,
N. Engl. J. Med. 2008; 358(10): p. 1018-1028
[NLRP5]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223877 | NLRP5 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 12,528.00 |
|
| RC223877L1 | Lenti-ORF clone of NLRP5 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 14,928.00 |
|
| RC223877L2 | Lenti-ORF clone of NLRP5 (mGFP-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 11,500.00 |
|
| RC223877L3 | Lenti-ORF clone of NLRP5 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 11,500.00 |
|
| RC223877L4 | Lenti-ORF clone of NLRP5 (mGFP-tagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 11,500.00 |
|
| RG223877 | NLRP5 (tGFP-tagged) - Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 14,128.00 |
|
| SC306608 | NLRP5 (untagged)-Human NLR family, pyrin domain containing 5 (NLRP5) |
CNY 12,344.00 |
