PHKA2 (NM_000292) Human Untagged Clone
CAT#: SC319895
PHKA2 (untagged)-Human phosphorylase kinase, alpha 2 (liver) (PHKA2)
CNY 8,608.00
Product images
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | GSD9A; PHK; PYK; PYKL; XLG; XLG2 |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for NM_000292.1
CGCGCCTCCCCGCCGCGCGGAGCTCTGGTTGGCTTGCTTTCCAACCGGACTTTGGGGCTA
GCGTTTAGAAAAGTCTCGACCTCCTCCGGCCCGGTCCCATCCCAAGAACCGACTAAGGCT GTGAGTGTCCGGGAACCAGACCCGCTTGGAGGCCACAGCCCCGACGTCCCGCGCCCACGC GGCAGATCGGGCGCTGCGGCCTGGGAGCCTCGGGGAGATGCGGAGCAGGAGCAATTCCGG GGTCCGCTTGGACGGGTACGCGCGGCTGGTGCAGCAAACCATCCTGTGTTACCAGAATCC CGTCACGGGGCTGCTGTCAGCCAGCCATGAGCAGAAGGATGCCTGGGTGCGGGATAACAT CTACAGTATCCTGGCCGTGTGGGGCCTGGGCATGGCCTACCGTAAGAATGCAGACCGCGA TGAGGACAAGGCCAAGGCCTACGAGCTGGAGCAGAACGTGGTGAAGCTGATGCGAGGTCT TCTCCAGTGCATGATGAGACAGGTGGCCAAAGTGGAGAAGTTCAAACACACTCAGAGCAC CAAGGACAGCCTGCACGCCAAGTACAACACCGCCACCTGTGGCACGGTGGTGGGCGACGA CCAGTGGGGCCACCTCCAGGTGGATGCCACCTCTCTCTTCCTCCTGTTCCTGGCCCAGAT GACCGCCTCAGGCTTACGTATCATTTTCACTCTCGATGAGGTGGCCTTCATACAGAATCT TGTCTTTTACATAGAAGCTGCATATAAAGTCGCTGATTATGGAATGTGGGAGCGTGGAGA TAAGACTAATCAGGGCATCCCGGAATTGAATGCAAGCTCCGTAGGAATGGCCAAGGCAGC TCTTGAGGCAATTGATGAACTGGACCTTTTTGGAGCCCATGGAGGACGCAAGTCAGTGAT TCATGTTCTGCCAGATGAGGTCGAGCACTGCCAGTCTATTCTGTTCTCCATGCTGCCAAG AGCGTCGACATCTAAAGAAATTGATGCTGGACTTCTTTCCATTATTTCCTTCCCGGCCTT TGCAGTGGAAGATGTAAACCTTGTAAATGTGACCAAAAATGAAATTATTTCTAAGCTCCA GGGGCGTTATGGATGCTGTCGCTTCCTTCGAGATGGTTATAAAACTCCAAGAGAGGACCC TAATCGACTGCATTATGACCCTGCTGAACTCAAGCTCTTCGAAAACATTGAATGTGAGTG GCCTGTGTTTTGGACATATTTTATAATAGATGGAGTCTTCAGTGGTGATGCTGTTCAGGT CCAAGAATACCGAGAGGCCCTGGAGGGAATACTCATCAGAGGCAAGAATGGGATCCGCCT GGTGCCTGAACTCTACGCTGTCCCGCCTAACAAGGTAGATGAAGAGTACAAGAATCCTCA CACAGTAGACCGAGTTCCTATGGGGAAGGTGCCTCATCTGTGGGGCCAATCCTTGTACAT CCTCAGCTCGCTGTTGGCAGAGGGATTCCTTGCCGCTGGTGAAATCGATCCCTTAAATAG AAGATTTTCCACTTCAGTCAAACCTGATGTTGTAGTACAAGTTACTGTTTTGGCAGAAAA CAATCACATTAAGGACTTATTGAGGAAACACGGGGTGAACGTCCAGAGTATCGCGGACAT TCATCCAATTCAAGTCCAGCCGGGCCGGATTCTTAGTCACATATATGCCAAGCTTGGACG GAATAAGAATATGAATTTGAGTGGGCGACCGTATCGACATATTGGTGTCCTTGGAACCTC TAAACTATATGTGATTAGGAACCAAATCTTTACTTTTACACCCCAGTTCACCGACGAGCA TCACTTCTACCTGGCCCTCGACAATGAGATGATCGTGGAGATGCTAAGGATCGAGCTGGC CTACCTGTGCACCTGCTGGAGGATGACGGGCAGACCCACACTCACCTTCCCCATCAGTCG CACCATGCTCACAAATGATGGCTCAGACATTCATTCTGCTGTGCTCTCCACAATTAGAAA ACTAGAGGATGGATATTTTGGAGGAGCCAGAGTAAAATTAGGGAACCTTTCGGAATTTCT CACCACATCGTTCTACACATATCTGACTTTTCTGGATCCAGACTGTGATGAGAAGTTGTT TGACAATGCCAGCGAAGGGACTTTCAGTCCTGATAGTGATTCAGATTTGGTAGGATATCT GGAAGACACCTGTAATCAAGAAAGCCAAGACGAACTTGACCATTATATCAACCACCTTCT GCAAAGCACATCGTTGAGGTCCTATCTGCCTCCTCTTTGTAAGAACACAGAAGACCGCCA TGTCTTCAGTGCTATCCACTCCACGCGGGACATACTTTCTGTGATGGCAAAAGCAAAGGG TTTGGAAGTTCCATTTGTTCCCATGACTTTGCCGACTAAAGTTCTAAGTGCCCACCGTAA ATCACTGAATCTTGTTGATTCTCCTCAGCCACTCCTAGAAAAGGTTCCTGAAAGTGACTT TCAGTGGCCCAGAGATGACCATAGTGACGTGGACTGTGAGAAGCTGGTTGAGCAGCTAAA AGATTGTTCGAACCTACAGGACCAAGCAGACATTCTGTACATTCTTTATGTCATAAAGGG TCCCAGCTGGGACACAAATCTCTCTGGACAGCACGGGGTCACCGTTCAAAACCTTCTTGG TGAGCTCTATGGGAAAGCCGGCTTGAACCAGGAGTGGGGTCTGATTCGCTACATCTCAGG CCTTCTCAGGAAGAAAGTGGAGGTCCTGGCTGAGGCCTGCACAGACCTGCTTTCGCACCA GAAGCAGCTCACCGTGGGCCTGCCGCCCGAGCCCCGGGAGAAGATCATCTCTGCGCCCCT TCCCCCAGAGGAGCTCACAAAACTCATCTACGAGGCCAGTGGGCAGGACATCAGCATTGC CGTCCTCACGCAGGAGATTGTGGTTTACCTGGCCATGTATGTCAGGGCGCAGCCCAGCCT CTTTGTGGAGATGCTGAGACTCCGGATTGGACTGATCATTCAGGTGATGGCCACGGAGCT GGCACGGAGCCTGAACTGCTCAGGAGAAGAGGCTTCTGAAAGTTTGATGAACCTCAGCCC TTTCGATATGAAAAATCTCCTGCACCATATTCTAAGTGGGAAAGAGTTTGGCGTTGAAAG AAGTGTGCGCCCTATCCACTCCTCCACATCCAGCCCTACCATCTCCATCCACGAGGTGGG CCATACCGGAGTCACCAAAACTGAGAGGAGTGGCATTAACAGACTGAGGAGTGAAATGAA ACAGATGACTAGGCGGTTTAGTGCTGATGAACAGTTCTTTTCTGTGGGCCAGGCCGCGTC CAGCAGTGCGCATTCCTCCAAGTCTGCGAGGTCCAGCACCCCATCCTCGCCCACTGGCAC GTCATCCTCAGACTCGGGAGGACATCACATCGGCTGGGGTGAGCGGCAGGGCCAGTGGCT GCGCAGGAGAAGGCTGGATGGGGCCATCAACAGGGTCCCCGTGGGATTCTACCAGAGGGT GTGGAAGATCCTCCAGAAGTGCCACGGTCTCTCCATCGATGGTTATGTCCTCCCATCCTC GACGACCCGAGAGATGACCCCGCATGAGATCAAGTTTGCTGTCCATGTCGAATCGGTGCT GAACCGCGTGCCGCAGCCCGAGTACCGGCAGCTGCTGGTGGAAGCCATCATGGTGCTGAC GCTGCTCTCGGACACGGAGATGACCAGCATCGGGGGCATCATCCACGTGGACCAGATCGT GCAGATGGCCAGTCAGCTGTTCTTGCAGGACCAGGTGTCAATTGGTGCCATGGACACCCT GGAGAAAGACCAAGCCACAGGAATCTGCCACTTCTTTTATGACAGCGCTCCGAGTGGGGC TTATGGGACGATGACCTACCTAACAAGAGCAGTGGCTTCTTATTTGCAGGAATTGTTGCC CAATTCGGGCTGCCAGATGCAATAGGGTCTCACCTGGAAACATGATCACACTCTCAATCT GTCACGTGCCCCCTAGCCTTACTGGGAACCTTCTGTCCCCCAAGATCCCCTGTGCTATCA GGAAAGCATGTCCCATCAGAAACACTCTCGGGGGGCAATGGTAGCACTCACCCTGAAACT GATGTATGTTAAAGCCACAGAGATAGAGCTGAGGAGTCCTGTGTTCCCCCGCAAGGAGCA CCCCGGGATCATTTTCTAGGTTCATTTCTCTGGAACATTTGCTGTAGCATCTGGTCTCAC GGACTCTGAGGAGGAATTGGAAATTGGTCTCTTTTGAGTGCAGAGGGAACTGAGACGCCA GCTTAAATTGGCTCTTGCAGAGAGTTACAGAAATAGTTTCGATGAGCTAGTGACACATCC TAAAGATGCAAAGATCCTCCTGGCGGCAGTAGCCTTGACAAGGGCCACCTCTTCACAGGA TGCAGTCTGTCTGTGCACCAAACTCTTCACCAAATAGAACACTTGTGTCTCTCTGTGAAG AAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_000292 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000292.1, NP_000283.1 |
RefSeq Size | 4566 bp |
RefSeq ORF | 3708 bp |
Locus ID | 5256 |
UniProt ID | P46019 |
Protein Families | Druggable Genome |
Protein Pathways | Calcium signaling pathway, Insulin signaling pathway |
Gene Summary | Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204185 | PHKA2 (Myc-DDK-tagged)-Human phosphorylase kinase, alpha 2 (liver) (PHKA2) |
CNY 8,600.00 |
|
RC204185L3 | Lenti ORF clone of Human phosphorylase kinase, alpha 2 (liver) (PHKA2), Myc-DDK-tagged |
CNY 12,450.00 |
|
RC204185L4 | Lenti ORF clone of Human phosphorylase kinase, alpha 2 (liver) (PHKA2), mGFP tagged |
CNY 12,450.00 |
|
RG204185 | PHKA2 (tGFP-tagged) - Human phosphorylase kinase, alpha 2 (liver) (PHKA2) |
CNY 11,590.00 |