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KHDRBS3 (NM_006558) Human Untagged Clone
CAT＃: SC320122
KHDRBS3 (untagged)-Human KH domain containing, RNA binding, signal transduction associated 3 (KHDRBS3)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Etle; etoile; SALP; SLM-2; SLM2; T-STAR; TSTAR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_006558.1
GGTGCGCGGGGCGGCGCGCGGCGTGCAGGTCGCAGCTGTGGCTCGGGTGCTGGCAGGTGC
TGGCGGGACTGGCGGGGATCGCCGTGGACTGCCTCAGGGGCGCCGCAGCCCGCTCGGCCC GAGGGCCCGCCTAACCGCGCCGCCCGCGCCCGCTCCTCCTCCCCGTGCGCCTGGAGTCCA CATCCCGGGCCCGGCGGCCGGCGAGCATGGAGGAGAAGTACCTGCCGGAGCTGATGGCGG AGAAGGACTCCCTGGACCCCTCCTTCACGCACGCCCTGCGCCTGGTGAACCAAGAAATAG AAAAGTTTCAAAAAGGAGAAGGCAAGGAAGAAAAGTACATCGATGTGGTGATTAATAAGA ACATGAAGCTGGGACAGAAAGTGTTAATTCCCGTAAAACAGTTCCCTAAGTTCAACTTTG TGGGGAAACTTTTGGGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCTTGA CAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAAGAAGAGTTGA GGAAAAGTGGAGAAGCGAAGTACTTCCATCTCAATGATGATCTCCATGTTCTCATTGAAG TGTTTGCCCCACCTGCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCAAAA AGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAGGAGTTAACAT ATTTGAATGGTGGTTCAGAAAATGCAGATGTTCCAGTGGTTCGAGGGAAACCCACCTTGC GTACAAGAGGTGTACCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCCGGC CAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTGTCCACCCGAG GGCCAGTGAGTCGGGGAAGAGGACTTCTCACTCCCAGAGCAAGAGGAGTCCCCCCAACTG GGTACAGACCTCCACCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTATGATG ATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCA CCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGACTT ATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGA CAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGT TGTGAAATAGCCAATCTCCACCAGTCCTGTATACTGTTCAAAGTAATTTTTTTCTATGAA CAATCCCTTTTTAAATAAATCAAAATGCTTAAAATCTGAATGGATGGAACTTAAAACTAC TTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAAAAGACATGTAAAATTTTGT TATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAAAGGAAAAAAAATAACTTTGATTA ACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAGC CTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGC TAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGGAAGCCAATTACAAGTGCAAATAA TGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCCT CTTGCTTGATACTAAATAAACTTTTGAAAGAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_006558 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006558.1, NP_006549.1 |
| RefSeq Size | 1963 bp |
| RefSeq ORF | 1041 bp |
| Locus ID | 10656 |
| UniProt ID | O75525 |
| Domains | KH |
| Gene Summary | RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6 (PubMed:10564820, PubMed:19561594, PubMed:26758068). Involved in splice site selection of vascular endothelial growth factor (PubMed:15901763). In vitro regulates CD44 alternative splicing by direct binding to purine-rich exonic enhancer (By similarity). Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners such as neuroligins and LRRTM family members (PubMed:26758068). Targeted, cell-type specific splicing regulation of NRXN1 at AS4 is involved in neuronal glutamatergic synapse function and plasticity (By similarity). May regulate expression of KHDRBS2/SLIM-1 in defined brain neuron populations by modifying its alternative splicing (By similarity). Can bind FABP9 mRNA (By similarity). May play a role as a negative regulator of cell growth. Inhibits cell proliferation.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209824 | KHDRBS3 (Myc-DDK-tagged)-Human KH domain containing, RNA binding, signal transduction associated 3 (KHDRBS3) |
CNY 3,656.00 |
|
| RC209824L1 | Lenti ORF clone of Human KH domain containing, RNA binding, signal transduction associated 3 (KHDRBS3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209824L2 | Lenti ORF clone of Human KH domain containing, RNA binding, signal transduction associated 3 (KHDRBS3), mGFP tagged |
CNY 5,890.00 |
|
| RC209824L3 | Lenti ORF clone of Human KH domain containing, RNA binding, signal transduction associated 3 (KHDRBS3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209824L4 | Lenti ORF clone of Human KH domain containing, RNA binding, signal transduction associated 3 (KHDRBS3), mGFP tagged |
CNY 5,890.00 |
|
| RG209824 | KHDRBS3 (tGFP-tagged) - Human KH domain containing, RNA binding, signal transduction associated 3 (KHDRBS3) |
CNY 4,370.00 |
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