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ZAK (MAP3K20) (NM_133646) Human Untagged Clone
CAT＃: SC320193
ZAK (untagged)-Human sterile alpha motif and leucine zipper containing kinase AZK (ZAK), transcript variant 2
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AZK; CNM6; MLK7; mlklak; MLT; MLTK; MLTKalpha; MLTKbeta; MRK; pk; SFMMP; ZAK |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_133646.2
GCCGCGCGGGCCGCTGTCGTCCCAACCCCCGCCGCCCTCGTCGCGCGCGGGGCCTCCGCG
CCCCCGGCTGCTGCTCACGCCCCGCCCGGGAGCCAGATTTTGTGGAAGTATAATACTTTG TCATTATGAGATGTCGTCTCTCGGTGCCTCCTTTGTGCAAATTAAATTTGATGACTTGCA GTTTTTTGAAAACTGCGGTGGAGGAAGTTTTGGGAGTGTTTATCGAGCCAAATGGATATC ACAGGACAAGGAGGTGGCTGTAAAGAAGCTCCTCAAAATAGAGAAAGAGGCAGAAATACT CAGTGTCCTCAGTCACAGAAACATCATCCAGTTTTATGGAGTAATTCTTGAACCTCCCAA CTATGGCATTGTCACAGAATATGCTTCTCTGGGATCACTCTATGATTACATTAACAGTAA CAGAAGTGAGGAGATGGATATGGATCACATTATGACCTGGGCCACTGATGTAGCCAAAGG AATGCATTATTTACATATGGAGGCTCCTGTCAAGGTGATTCACAGAGACCTCAAGTCAAG AAACGTTGTTATAGCTGCTGATGGAGTATTGAAGATCTGTGACTTTGGTGCCTCTCGGTT CCATAACCATACAACACACATGTCCTTGGTTGGAACTTTCCCATGGATGGCTCCAGAAGT TATCCAGAGTCTCCCTGTGTCAGAAACTTGTGACACATATTCCTATGGTGTGGTTCTCTG GGAGATGCTAACAAGGGAGGTCCCCTTTAAAGGTTTGGAAGGATTACAAGTAGCTTGGCT TGTAGTGGAAAAAAACGAGAGATTAACCATTCCAAGCAGTTGCCCCAGAAGTTTTGCTGA ACTGTTACATCAGTGTTGGGAAGCTGATGCCAAGAAACGGCCATCATTCAAGCAAATCAT TTCAATCCTGGAGTCCATGTCAAATGACACGAGCCTTCCTGACAAGTGTAACTCATTCCT ACACAACAAGGCGGAGTGGAGGTGCGAAATTGAGGCAACTCTTGAGAGGCTAAAGAAACT AGAGCGTGATCTCAGCTTTAAGGAGCAGGAGCTTAAAGAACGAGAAAGACGTTTAAAGAT GTGGGAGCAAAAGCTGACAGAGCAGTCCAACACCCCGCTTCTCTTGCCTCTTGCTGCAAG AATGTCTGAGGAGTCTTACTTTGAATCTAAAACAGAGGAGTCAAACAGTGCAGAGATGTC ATGTCAGATCACAGCAACAAGTAACGGGGAGGGCCATGGCATGAACCCAAGTCTGCAGGC CATGATGCTGATGGGCTTTGGGGATATCTTCTCAATGAACAAAGCAGGAGCTGTGATGCA TTCTGGGATGCAGATAAACATGCAAGCCAAGCAGAATTCTTCCAAAACCACATCTAAGAG AAGGGGGAAGAAAGTCAACATGGCTCTGGGGTTCAGTGATTTTGACTTGTCAGAAGGTGA CGATGATGATGATGATGACGGTGAGGAGGAGGATAATGACATGGATAATAGTGAATGAAA GCAGAAAGCAAAGTAATAAAATCACAAATGTTTGGAAAACACAAAAAAAAAAAAAAAAAA AA |
| Restriction Sites | Please inquire |
| ACCN | NM_133646 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_133646.2, NP_598407.1 |
| RefSeq Size | 7194 bp |
| RefSeq ORF | 1368 bp |
| Locus ID | 51776 |
| UniProt ID | Q9NYL2 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | MAPK signaling pathway, Tight junction |
| Gene Summary | This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks several exons in the coding region and contains a different 3' exon compared to variant 1. The resulting protein (isoform 2, also referred to as MRK-beta, MLTK-beta and MLK7) is shorter and has a distinct C-terminus compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200069 | ZAK (Myc-DDK-tagged)-Human sterile alpha motif and leucine zipper containing kinase AZK (ZAK), transcript variant 2 |
CNY 3,656.00 |
|
| RC200069L1 | Lenti ORF clone of Human sterile alpha motif and leucine zipper containing kinase AZK (ZAK), transcript variant 2, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC200069L2 | Lenti ORF clone of Human sterile alpha motif and leucine zipper containing kinase AZK (ZAK), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC200069L3 | Lenti ORF clone of Human sterile alpha motif and leucine zipper containing kinase AZK (ZAK), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200069L4 | Lenti ORF clone of Human sterile alpha motif and leucine zipper containing kinase AZK (ZAK), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG200069 | ZAK (tGFP-tagged) - Human sterile alpha motif and leucine zipper containing kinase AZK (ZAK), transcript variant 2 |
CNY 5,256.00 |
